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NCT05368987 · ClinicalTrials.gov registry record · NA

Neuromodulation of the Fear Extinction Circuit Using Temporally and Anatomically Specific TMS in Humans

A NA study of PTSD, sponsored by The University of Texas Health Science Center, Houston.

Recruiting
Registry status
NA
Development phase
250
Enrollment target
1
Study location

NCT05368987 is a NA study of PTSD that is actively recruiting participants, run by The University of Texas Health Science Center, Houston. The registered enrollment target is 250 participants, below the 300-participant average among 154 other PTSD trials with a reported enrollment target (17% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05368987, a NA study of PTSD, is actively recruiting participants, sponsored by The University of Texas Health Science Center, Houston.

RECRUITING
Registry status
NA
Development phase
250 participants
Enrollment target
1
Study location

Study Summary

This study aims to explore the mechanisms of how transcranial magnetic stimulation (TMS) impacts fear circuits. The overarching objectives are to understand how varying TMS parameters affect targeted brain regions in order to optimize its impact on enhancing fear extinction memory consolidation in a population with known fear extinction deficiencies: post-traumatic stress disorder (PTSD). 250 subjects will take part in this research study across UTHealth Houston. The study will include preliminary screenings, baseline visits, and experimental visits across four days

Conditions Studied

Interventions

  • DEVICE Transcranial magnetic stimulation (TMS)
  • BEHAVIORAL Fear Conditioning and Extinction Paradigm

Study Locations (1)

Texas

  • UTHealth Houston - Houston

Trial Details

FieldValue
Enrollment Target 250 participants
Start Date 2022-02-01
Est. Completion 2027-09-30
Phase NA

What the Registry Record Tells You About NCT05368987

The ClinicalTrials.gov registry entry for NCT05368987 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 250 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 300-participant average among 154 other PTSD trials with a reported enrollment target (17% lower). The listed sponsor is The University of Texas Health Science Center, Houston, which has 732 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with PTSD appearing as the primary indexed condition, and to 2 interventions - of which Transcranial magnetic stimulation (TMS) is the first listed.

NCT05368987 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT05368987 about?

NCT05368987 is a clinical study titled "Neuromodulation of the Fear Extinction Circuit Using Temporally and Anatomically Specific TMS in Humans". This study aims to explore the mechanisms of how transcranial magnetic stimulation (TMS) impacts fear circuits. The overarching objectives are to understand how varying TMS parameters affect targeted brain regions in order to optimize its impact on enhancing fear extinction memory consolidation in a...

What is the current status of trial NCT05368987?

This trial is currently recruiting. It is a NA study. The enrollment target is 250 participants. The study started on 2022-02-01. Estimated completion is 2027-09-30.

What conditions does trial NCT05368987 study?

This clinical trial studies the following conditions: PTSD.

What interventions are being tested in trial NCT05368987?

The interventions under investigation include: Transcranial magnetic stimulation (TMS) (DEVICE), Fear Conditioning and Extinction Paradigm (BEHAVIORAL).

Who is sponsoring clinical trial NCT05368987?

This trial is sponsored by The University of Texas Health Science Center, Houston, which has 732 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05368987 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.