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ClinicalTrials.gov 64 recruiting now official registry

Stress clinical trials

64 of 153 indexed Stress trials are currently recruiting.

153 US clinical trials · 64 currently recruiting

Stress is the subject of 153 registered US clinical trials on ClinicalTrials.gov, 64 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most active sponsor is Virginia Commonwealth University, running 5 of these trials.

The research picture

Stress has 153 registered US clinical trials, 64 of them open to new participants right now, about 42% of the total.

64
recruiting participants now
42%
of trials open to enrollment
2
in Phase 3–4 (later-stage)
5
top sponsor: Virginia Commonwealth University
Phase 16Phase 26Phase 42

Active & Recent Trials

153 total, page 1 of 4

RECRUITING NA 80,800 participants

Building Resilience at Schools: Emotional and Biological Assessment and Treatment of Traumatic Stress

Stanford University

NCT05701111

RECRUITING 1,000 participants

Technology Exposure and Child Health: Wellness Impact and Social Effects: an Observational Product Registry Study

Aura

NCT06664944

RECRUITING NA 900 participants

State-dependent Interoception, Value-based Decision-making, and Introspection

National Institute of Mental Health (NIMH)

NCT05666726

RECRUITING NA 500 participants

Internet Based Psychological Support

Dartmouth-Hitchcock Medical Center

NCT02726061

RECRUITING NA 400 participants

Adaptive Coping Skills Training to Improve Psychological Distress Among Cardiorespiratory Failure Survivors

Duke University

NCT06538246

RECRUITING NA 384 participants

Cocooned Moms Study

InovCares Connected Comprehensive Healthcare Corporation

NCT06968650

RECRUITING NA 325 participants

Promoting Resilience in Early Survivorship Among Adolescents and Young Adults With Cancer

Dana-Farber Cancer Institute

NCT06038318

RECRUITING NA 300 participants

Sleep and Morning Wellbeing Study

Athletic Greens International

NCT07311434

RECRUITING NA 300 participants

Heart Math Resilience Program on Jail Staff

Florida State University

NCT06928610

RECRUITING NA 300 participants

The Impact of a Race-Based Stress Reduction Intervention

Loyola University

NCT05902741

RECRUITING NA 270 participants

Smartphone-based Cognitive Emotion Regulation Training for Unpaid Primary Caregivers of Persons With Alzheimer's Disease

Bryan Denny

NCT05949047

RECRUITING NA 243 participants

The Impact of Music Medicine on Preterm Brain Development and Behavior

Brigham and Women's Hospital

NCT06536296

RECRUITING NA 226 participants

Digital Single Session Intervention for Youth Mental Health

Harvard University

NCT05449002

RECRUITING NA 200 participants

A Study of Oral Kavalactones Effect on Nurses

Mayo Clinic

NCT06177535

RECRUITING 200 participants

Neonatal Neurodevelopmental Outcomes

Baylor College of Medicine

NCT07101757

RECRUITING NA 180 participants

Stress Phenotypes and Preterm Birth

Columbia University

NCT05229666

RECRUITING NA 166 participants

Perceptual Influences From Smoking Cannabis: an Experimental Study

University of Colorado, Boulder

NCT06588582

RECRUITING NA 160 participants

The Student Wellness and Emotional Growth Resiliency (SWAG-R) Program

Nova Southeastern University

NCT06652503

RECRUITING Phase 1 160 participants

Study of Cannabidiol and Neuroimaging on Stress

Icahn School of Medicine at Mount Sinai

NCT07278505

RECRUITING NA 150 participants

Resilience Through Interventions for Successful Early Outcomes

University of North Carolina, Chapel Hill

NCT06669624

RECRUITING NA 132 participants

A Randomized Controlled Trial to Assess the Impact of Live and Recorded Music-Based Interventions on Pre-operative Stress, Mood, Pain and Biomarkers, in Neurosurgical Patients (Music-STAR Trial)

M.D. Anderson Cancer Center

NCT06536504

RECRUITING NA 130 participants

Stop, Focus, Plan, and Change: Predicting Parent and Child Responses to a Brief, Telehealth Parent Training

University of Colorado, Denver

NCT06505980

RECRUITING NA 125 participants

Cannabidiol (CBD) and Stress Response: Psychobiological Mechanisms

University of Minnesota

NCT07069478

RECRUITING NA 120 participants

Mindfulness-Based Intervention With a Supplement for Stress-Related Problems in College Students Across Multiple Sites (4SITE)

Colorado State University

NCT07098845

RECRUITING 120 participants

Cardiovascular Health & Early Stress

Virginia Commonwealth University

NCT06557707

RECRUITING NA 120 participants

Stress and Pain in People Living With HIV

Yale University

NCT06784908

RECRUITING NA 120 participants

Stress and Opioid Misuse Risk: The Role of Endogenous Opioid and Endocannabinoid Mechanisms

Vanderbilt University Medical Center

NCT05142267

RECRUITING NA 100 participants

Sound Stops Stress Study: Evaluating the WAVwatch Effect

Efforia

NCT07281989

RECRUITING NA 100 participants

Randomized Controlled Trial of a Behavioral Training App

New York University

NCT06447909

RECRUITING NA 100 participants

My ESSENCE - A Research Study on Mindfulness for African-Americans With Type 2 Diabetes

University of Illinois at Chicago

NCT05208164

RECRUITING Phase 1 90 participants

Effects of Cannabidiol on Stress and Nicotine Withdrawal

Johns Hopkins University

NCT07001930

RECRUITING NA 80 participants

Asthma Intervention With Residential Ventilation and Air Cleaner (AIRVAC) Study

The University of Texas at Arlington

NCT07196436

RECRUITING NA 80 participants

Stress Management Program

Stanford University

NCT06526585

RECRUITING NA 70 participants

Impact of Serial Bedside Video Calls on Stress Level in Parents of Infants Admitted to NICU

Cook County Health

NCT06252883

RECRUITING NA 66 participants

The Effect of a Mindset Management Approach on Stress Levels in Women With Infertility

Virginia Polytechnic Institute and State University

NCT05997407

RECRUITING Phase 2 64 participants

Using Life's Essential 8 in Midlife Black Women

Ohio State University

NCT06707636

RECRUITING NA 62 participants

Student Exercise and Sleep Timing Study - Part 2

Rutgers, The State University of New Jersey

NCT06336590

RECRUITING NA 60 participants

Scalable Intervention for Stress Management

Livotion

NCT07127575

RECRUITING NA 60 participants

Aimmune Longitudinal Collaboration Study

Aimmune Therapeutics

NCT07218640

RECRUITING NA 60 participants

Parenting Stress mHealth

University of California, San Francisco

NCT05032742

RECRUITING NA 60 participants

Effects of Ashwagandha Extract on Stress Levels

Nutraceuticals Research Institute

NCT06793891

RECRUITING NA 60 participants

ACT Together: Implementing a Web-Based Program With Brief Coaching for Parents of Children With Disabilities in Pediatric Outpatient Clinics

University of South Florida

NCT07360600

RECRUITING NA 53 participants

Evaluating the Impact of SKY Breath Meditation on Stress, Well-being, and Connection in College Students

University of Alabama, Tuscaloo

NCT07415460

RECRUITING NA 51 participants

Efficacy and Safety of a Proprietary Blend of Ashwagandha Root Extract (Aqueous) in Adult Men and Women With High Stress and Anxiety: A Randomized, Double-blind, Three-arm, Parallel, Placebo-controlled Study

SF Research Institute

NCT06714942

RECRUITING NA 50 participants

Digital Intervention for Physical Activity

Auburn University

NCT07130734

RECRUITING NA 50 participants

The Effects of Mindfulness Practice With Tao Art (Love Peace Harmony Calligraphy and Song) on Well-being

Sha Research Foundation

NCT06803641

RECRUITING NA 50 participants

Sleep Well Firefighters: An App-based Program to Improve Sleep, Cognition, and Behavioral Health in Firefighters

California Polytechnic State University-San Luis Obispo

NCT07477184

RECRUITING NA 50 participants

Feasibility of a Prenatal Yoga Mobile App in African American Pregnant Women

San Diego State University

NCT06353113

RECRUITING NA 48 participants

Adapting a Stress Management Intervention to Reduce Cardiovascular Disease Risk

University of Alabama at Birmingham

NCT06811896

RECRUITING NA 44 participants

Assessing MB-Spirit for Psychological Well-being

Sara W Lazar

NCT07325448

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Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 6
Phase 4 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Stress Trial Landscape

153 indexed Stress studies · 64 recruiting (42%).

Phase mix: 2 late (III/IV) vs 12 early (I/II).

Top sponsor: Virginia Commonwealth University (5 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Stress?

PlainTrial tracks 153 US clinical trials for Stress, of which 64 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Stress?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.