Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Stress: early-phase trial registry
64 of 153 indexed Stress trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #73 of 28,707 conditions by registered trial count.
153 US clinical trials · 64 currently recruiting · #73 of 28,707 conditions by registered trial count
Stress: 153 US clinical trials tracked, 64 recruiting.
Stress is the subject of 153 registered US clinical trials on ClinicalTrials.gov, 64 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most active sponsor is Virginia Commonwealth University, running 5 of these trials.
Enrollment posture brief
Registry condition stress
OPEN 64 | RECR 42% | LATE 2 | EARLY 12 | RANK #73 | SPON 5
Volume-matched condition peers
Nearest open-share peer: Colorectal Neoplasms (42% recruiting · 55 trials)
Stress lists 64 open slots (42% of 153 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Stress on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Stress is recruiting above its size-band peers.
64 of 153 indexed trials (41.8%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Stress trials is spread across many organizations.
Virginia Commonwealth University accounts for 5 of 153 trials (3.3%). 113 distinct sponsors appear on at least one study for this condition label.
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Typical Stress enrolment sits around 80 participants.
Median target enrolment is 80 among the 153 trials that report a genuine target (sentinel values excluded). 86 of those (56.2%) plan for fewer than 100 participants.
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Stress research is mostly interventional.
142 interventional and 11 observational studies make up this index (92.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
153 total, page 1 of 4
Building Resilience at Schools: Emotional and Biological Assessment and Treatment of Traumatic Stress
Stanford University
NCT05701111
Technology Exposure and Child Health: Wellness Impact and Social Effects: an Observational Product Registry Study
Aura
NCT06664944
State-dependent Interoception, Value-based Decision-making, and Introspection
National Institute of Mental Health (NIMH)
NCT05666726
Internet Based Psychological Support
Dartmouth-Hitchcock Medical Center
NCT02726061
Adaptive Coping Skills Training to Improve Psychological Distress Among Cardiorespiratory Failure Survivors
Duke University
NCT06538246
Cocooned Moms Study
InovCares Connected Comprehensive Healthcare Corporation
NCT06968650
Promoting Resilience in Early Survivorship Among Adolescents and Young Adults With Cancer
Dana-Farber Cancer Institute
NCT06038318
Sleep and Morning Wellbeing Study
Athletic Greens International
NCT07311434
Heart Math Resilience Program on Jail Staff
Florida State University
NCT06928610
The Impact of a Race-Based Stress Reduction Intervention
Loyola University
NCT05902741
Smartphone-based Cognitive Emotion Regulation Training for Unpaid Primary Caregivers of Persons With Alzheimer's Disease
Bryan Denny
NCT05949047
The Impact of Music Medicine on Preterm Brain Development and Behavior
Brigham and Women's Hospital
NCT06536296
Digital Single Session Intervention for Youth Mental Health
Harvard University
NCT05449002
A Study of Oral Kavalactones Effect on Nurses
Mayo Clinic
NCT06177535
Neonatal Neurodevelopmental Outcomes
Baylor College of Medicine
NCT07101757
Stress Phenotypes and Preterm Birth
Columbia University
NCT05229666
Perceptual Influences From Smoking Cannabis: an Experimental Study
University of Colorado, Boulder
NCT06588582
The Student Wellness and Emotional Growth Resiliency (SWAG-R) Program
Nova Southeastern University
NCT06652503
Study of Cannabidiol and Neuroimaging on Stress
Icahn School of Medicine at Mount Sinai
NCT07278505
Resilience Through Interventions for Successful Early Outcomes
University of North Carolina, Chapel Hill
NCT06669624
A Randomized Controlled Trial to Assess the Impact of Live and Recorded Music-Based Interventions on Pre-operative Stress, Mood, Pain and Biomarkers, in Neurosurgical Patients (Music-STAR Trial)
M.D. Anderson Cancer Center
NCT06536504
Stop, Focus, Plan, and Change: Predicting Parent and Child Responses to a Brief, Telehealth Parent Training
University of Colorado, Denver
NCT06505980
Cannabidiol (CBD) and Stress Response: Psychobiological Mechanisms
University of Minnesota
NCT07069478
Mindfulness-Based Intervention With a Supplement for Stress-Related Problems in College Students Across Multiple Sites (4SITE)
Colorado State University
NCT07098845
Cardiovascular Health & Early Stress
Virginia Commonwealth University
NCT06557707
Stress and Pain in People Living With HIV
Yale University
NCT06784908
Stress and Opioid Misuse Risk: The Role of Endogenous Opioid and Endocannabinoid Mechanisms
Vanderbilt University Medical Center
NCT05142267
Sound Stops Stress Study: Evaluating the WAVwatch Effect
Efforia
NCT07281989
Randomized Controlled Trial of a Behavioral Training App
New York University
NCT06447909
My ESSENCE - A Research Study on Mindfulness for African-Americans With Type 2 Diabetes
University of Illinois at Chicago
NCT05208164
Effects of Cannabidiol on Stress and Nicotine Withdrawal
Johns Hopkins University
NCT07001930
Asthma Intervention With Residential Ventilation and Air Cleaner (AIRVAC) Study
The University of Texas at Arlington
NCT07196436
Stress Management Program
Stanford University
NCT06526585
Impact of Serial Bedside Video Calls on Stress Level in Parents of Infants Admitted to NICU
Cook County Health
NCT06252883
The Effect of a Mindset Management Approach on Stress Levels in Women With Infertility
Virginia Polytechnic Institute and State University
NCT05997407
Using Life's Essential 8 in Midlife Black Women
Ohio State University
NCT06707636
Student Exercise and Sleep Timing Study - Part 2
Rutgers, The State University of New Jersey
NCT06336590
Scalable Intervention for Stress Management
Livotion
NCT07127575
Aimmune Longitudinal Collaboration Study
Aimmune Therapeutics
NCT07218640
Parenting Stress mHealth
University of California, San Francisco
NCT05032742
Effects of Ashwagandha Extract on Stress Levels
Nutraceuticals Research Institute
NCT06793891
ACT Together: Implementing a Web-Based Program With Brief Coaching for Parents of Children With Disabilities in Pediatric Outpatient Clinics
University of South Florida
NCT07360600
Evaluating the Impact of SKY Breath Meditation on Stress, Well-being, and Connection in College Students
University of Alabama, Tuscaloo
NCT07415460
Efficacy and Safety of a Proprietary Blend of Ashwagandha Root Extract (Aqueous) in Adult Men and Women With High Stress and Anxiety: A Randomized, Double-blind, Three-arm, Parallel, Placebo-controlled Study
SF Research Institute
NCT06714942
Digital Intervention for Physical Activity
Auburn University
NCT07130734
The Effects of Mindfulness Practice With Tao Art (Love Peace Harmony Calligraphy and Song) on Well-being
Sha Research Foundation
NCT06803641
Sleep Well Firefighters: An App-based Program to Improve Sleep, Cognition, and Behavioral Health in Firefighters
California Polytechnic State University-San Luis Obispo
NCT07477184
Feasibility of a Prenatal Yoga Mobile App in African American Pregnant Women
San Diego State University
NCT06353113
Adapting a Stress Management Intervention to Reduce Cardiovascular Disease Risk
University of Alabama at Birmingham
NCT06811896
Assessing MB-Spirit for Psychological Well-being
Sara W Lazar
NCT07325448
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 6 |
| Phase 2 | 6 |
| Phase 4 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Stress records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Stress trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Stress page
153 registered trials, 64 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 64 Stress trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Virginia Commonwealth University sponsors the most Stress trials on record, review their full trial history before evaluating a specific study. See Virginia Commonwealth University's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Stress condition card totals 153 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.