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NCT04454450 · ClinicalTrials.gov registry record · NA
Using Advanced Imaging Studies to Develop a Profile of High-grade Serous Ovarian Cancer
A NA study of Ovarian Cancer and High Grade Ovarian Serous, sponsored by Memorial Sloan Kettering Cancer Center.
- Active
- Registry status
- NA
- Development phase
- 10
- Enrollment target
- 1
- Study location
NCT04454450: Active NA study of Ovarian Cancer and High Grade Ovarian Serous, sponsored by Memorial Sloan Kettering Cancer Center.
NCT04454450 is a NA study of Ovarian Cancer and High Grade Ovarian Serous that is active but no longer recruiting, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 10 participants, below the 729-participant average among 322 other Ovarian Cancer trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04454450, a NA study of Ovarian Cancer and High Grade Ovarian Serous, is active but no longer recruiting, sponsored by Memorial Sloan Kettering Cancer Center.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 10 participants
- Enrollment target
- 1
- Study location
Study Summary
The researchers are doing this study to find out whether the researchers can combine information provided by PET/MRI scans with information from tests on blood and tissue samples to develop a very detailed description (profile) of high-grade serous ovarian carcinoma (HGSOC), which could improve our ability to treat this disease. The study researchers will use computers to analyze the combined results of the imaging tests and the genetic and immune system tests on the tumor samples. The study researchers think that this information will help them more accurately predict the way tumors respond to treatment, which may improve their ability to individualize treatments for this disease.
Primary Outcome
Radiologist-defined tumor volumes will be used to train and validate a machine learning algorithm for generating segmentations. The data will be split into 70%-30% of training and test sets, respectively. The comparisons will be performed on a slice-by-slice and lesion-bylesion basis, which should ensure sufficient numbers of examples for testing.
Conditions Studied
Interventions
- DIAGNOSTIC_TEST PET/MRI
- DIAGNOSTIC_TEST Contrast enhanced CT
Study Locations (1)
New York
- Memorial Sloan Kettering Cancer Center (All Protocol Activities) - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2020-06-22 |
| Est. Completion | 2026-06 |
| Phase | NA |
What the registry record for NCT04454450 still lists
NCT04454450 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 729-participant average among 322 other Ovarian Cancer trials with a reported enrollment target (99% lower).
The record links to 2 conditions, with Ovarian Cancer appearing as the primary indexed condition, and to 2 interventions - of which PET/MRI is the first listed.
NCT04454450 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT04454450 about?
NCT04454450 is a clinical study titled "Using Advanced Imaging Studies to Develop a Profile of High-grade Serous Ovarian Cancer". The researchers are doing this study to find out whether the researchers can combine information provided by PET/MRI scans with information from tests on blood and tissue samples to develop a very detailed description (profile) of high-grade serous ovarian carcinoma (HGSOC), which could improve our ...
What is the current status of trial NCT04454450?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 10 participants. The study started on 2020-06-22. Estimated completion is 2026-06.
What conditions does trial NCT04454450 study?
This clinical trial studies the following conditions: Ovarian Cancer, High Grade Ovarian Serous.
What interventions are being tested in trial NCT04454450?
The interventions under investigation include: PET/MRI (DIAGNOSTIC_TEST), Contrast enhanced CT (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT04454450?
This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04454450 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT04454450's enrollment target sits among peer trials
10 307th of 322 higher than 11 of 322 other Ovarian Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Ovarian Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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