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NCT04024878 · ClinicalTrials.gov registry record · Phase 1

NeoVax With Nivolumab in Patients With Ovarian Cancer

A Phase 1 study of Ovarian Cancer, sponsored by Dana-Farber Cancer Institute.

Active
Registry status
Phase 1
Development phase
22
Enrollment target
1
Study location

NCT04024878: Active Phase 1 study of Ovarian Cancer, sponsored by Dana-Farber Cancer Institute.

NCT04024878 is a Phase 1 study of Ovarian Cancer that is active but no longer recruiting, run by Dana-Farber Cancer Institute. The registered enrollment target is 22 participants, below the 729-participant average among 322 other Ovarian Cancer trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04024878, a Phase 1 study of Ovarian Cancer, is active but no longer recruiting, sponsored by Dana-Farber Cancer Institute.

ACTIVE NOT RECRUITING
Registry status
Phase 1
Development phase
22 participants
Enrollment target
1
Study location

Study Summary

This research study is evaluating a new type of vaccine called "Personalized NeoAntigen Cancer Vaccine" in combination with Nivolumab (Opdivo®) for ovarian cancer.

Primary Outcome

To demonstrate that regimen of NeoVax with Nivolumab is feasible and safe for the treatment of patients with ovarian cancer.

Conditions Studied

Interventions

  • DRUG Nivolumab
  • BIOLOGICAL NeoVax
  • PROCEDURE Core Needle Biopsy

Study Locations (1)

Massachusetts

  • Dana Farber Cancer Institute - Boston

Trial Details

FieldValue
Enrollment Target 22 participants
Start Date 2020-11-20
Est. Completion 2029-04-30
Phase Phase 1
Dana-Farber Cancer Institute

781 total trials

What the registry record for NCT04024878 still lists

NCT04024878 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 22 participants, a relatively small participant target, below the 729-participant average among 322 other Ovarian Cancer trials with a reported enrollment target (97% lower).

The record links to 1 condition, with Ovarian Cancer appearing as the primary indexed condition, and to 3 interventions - of which Nivolumab is the first listed.

NCT04024878 reports a single indexed study location in Massachusetts.

Frequently Asked Questions

What is clinical trial NCT04024878 about?

NCT04024878 is a clinical study titled "NeoVax With Nivolumab in Patients With Ovarian Cancer". This research study is evaluating a new type of vaccine called "Personalized NeoAntigen Cancer Vaccine" in combination with Nivolumab (Opdivo®) for ovarian cancer.

What is the current status of trial NCT04024878?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 22 participants. The study started on 2020-11-20. Estimated completion is 2029-04-30.

What conditions does trial NCT04024878 study?

This clinical trial studies the following conditions: Ovarian Cancer.

What interventions are being tested in trial NCT04024878?

The interventions under investigation include: Nivolumab (DRUG), NeoVax (BIOLOGICAL), Core Needle Biopsy (PROCEDURE).

Who is sponsoring clinical trial NCT04024878?

This trial is sponsored by Dana-Farber Cancer Institute, which has 781 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04024878 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Ovarian Cancer

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04024878's enrollment target sits among peer trials

22 276th of 322 higher than 44 of 322 other Ovarian Cancer trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Ovarian Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04024878, the US trial registry maintained by the National Library of Medicine. NCT04024878 (small enrollment · single site footprint · active not recruiting) retrieved and formatted by PlainTrial, see methodology.