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NCT00889382 · ClinicalTrials.gov registry record · Phase 1

A Study Evaluating Intermittent and Continuous OSI-906 and Weekly Paclitaxel in Patients With Recurrent Epithelial Ovarian Cancer (and Other Solid Tumors)

A Phase 1 study of Ovarian Cancer and Solid Tumors, sponsored by Astellas Pharma.

Completed
Registry status
Phase 1
Development phase
152
Enrollment target
20
Study locations

NCT00889382 is a Phase 1 study of Ovarian Cancer and Solid Tumors that has completed, run by Astellas Pharma. The registered enrollment target is 152 participants, below the 728-participant average among 322 other Ovarian Cancer trials with a reported enrollment target (79% lower). The trial reports 20 study locations across 15 states.

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The verdict

NCT00889382, a Phase 1 study of Ovarian Cancer and Solid Tumors, has completed, sponsored by Astellas Pharma.

COMPLETED
Registry status
Phase 1
Development phase
152 participants
Enrollment target
20
Study locations

Study Summary

This is a multi-center, randomized, open-label, phase 1/2 study of continuous weekly paclitaxel and escalating doses of intermittent or continuous OSI-906 in patients with recurrent/relapsed ovarian and other solid tumors.

Interventions

  • DRUG Paclitaxel
  • DRUG OSI-906

Study Locations (20)

Western Australia

  • St. John of God Hospital, Bunbury - Bunbury
  • Sir Charles Gairdner Hospital - Perth
  • St. John of Gog Hospital, Subiaco - Subiaco

North Carolina

  • Blumenthal Cancer Center - Main - Charlotte
  • Duke University Medical Center - Durham

Victoria

  • Frankston Hospital - Frankston
  • Border Medical Oncology - Wodonga

Ontario

  • Juravinski Cancer Center - Hamilton
  • Princess Margaret Hospital - Toronto

Arizona

  • Mayo Clinic - Scottsdale

California

  • Department of Obstetrics and Gynecology, University of California, Irvine - Orange

Indiana

  • Horizon Oncology Center - Lafayette

Louisiana

  • Ochsner Clinic Foundation - New Orleans

Trial Details

FieldValue
Enrollment Target 152 participants
Start Date 2009-08-05
Est. Completion 2014-08-25
Phase Phase 1

Sponsor

Astellas Pharma

165 total trials

What the Registry Record Tells You About NCT00889382

The ClinicalTrials.gov registry entry for NCT00889382 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 152 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 728-participant average among 322 other Ovarian Cancer trials with a reported enrollment target (79% lower). The listed sponsor is Astellas Pharma, which has 165 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Ovarian Cancer appearing as the primary indexed condition, and to 2 interventions - of which Paclitaxel is the first listed.

NCT00889382 reports 20 study locations spanning 15 distinct geographic areas - top geographies include Western Australia, North Carolina, Victoria.

Frequently Asked Questions

What is clinical trial NCT00889382 about?

NCT00889382 is a clinical study titled "A Study Evaluating Intermittent and Continuous OSI-906 and Weekly Paclitaxel in Patients With Recurrent Epithelial Ovarian Cancer (and Other Solid Tumors)". This is a multi-center, randomized, open-label, phase 1/2 study of continuous weekly paclitaxel and escalating doses of intermittent or continuous OSI-906 in patients with recurrent/relapsed ovarian and other solid tumors.

What is the current status of trial NCT00889382?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 152 participants. The study started on 2009-08-05. Estimated completion is 2014-08-25.

What conditions does trial NCT00889382 study?

This clinical trial studies the following conditions: Ovarian Cancer, Solid Tumors.

What interventions are being tested in trial NCT00889382?

The interventions under investigation include: Paclitaxel (DRUG), OSI-906 (DRUG).

Who is sponsoring clinical trial NCT00889382?

This trial is sponsored by Astellas Pharma, which has 165 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00889382 being conducted?

This trial has 20 study locations across Arizona, California, Indiana, Louisiana, New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.