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NCT00699907 · ClinicalTrials.gov registry record · Phase 2
Effect of Flutamide on Biomarkers in Blood and Tissue Samples From Patients at High Risk of Ovarian Cancer
A Phase 2 study of Ovarian Cancer, sponsored by University of Arizona.
- Completed
- Registry status
- Phase 2
- Development phase
- 127
- Enrollment target
- 1
- Study location
NCT00699907: Completed Phase 2 study of Ovarian Cancer, sponsored by University of Arizona.
NCT00699907 is a Phase 2 study of Ovarian Cancer that has completed, run by University of Arizona. The registered enrollment target is 127 participants, below the 728-participant average among 322 other Ovarian Cancer trials with a reported enrollment target (83% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00699907, a Phase 2 study of Ovarian Cancer, has completed, sponsored by University of Arizona.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 127 participants
- Enrollment target
- 1
- Study location
Study Summary
Studying samples of blood and tissue in the laboratory from patients with a high risk of developing ovarian cancer may help doctors identify and learn more about biomarkers related to cancer. We hypothesized that (i) preclinical biologic evidence exists for the role of androgens in ovarian cancer development and (ii) flutamide treatment of women at high risk for ovarian cancer may identify meaningful tissue biomarkers of androgen action and of ovarian cancer initiation. This phase II trial studied the effect of flutamide on biomarkers in blood and tissue samples from patients at high risk of ovarian cancer.
Primary Outcome
CSF-1 levels were measured by immunohistochemistry (IHC). The modified H-Score assess extent of nuclear immunoreactivity applicable to steroid receptors. The modified H-scores total range is 0-300. A lower modified H-score indicates weakly staining nuclei. A higher modified H-score indicated strongly staining nuclei. This applies to all measures.
Conditions Studied
Interventions
- DRUG flutamide
Study Locations (1)
Arizona
- University of Arizona Cancer Center - Tucson
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 127 participants |
| Start Date | 2005-01 |
| Est. Completion | 2014-11 |
| Phase | Phase 2 |
What the finished NCT00699907 record still lists
NCT00699907 is an interventional study that assigns participants to a tested intervention. The registered 127 participants enrollment target is mid-sized for trials with a published cap, below the 728-participant average among 322 other Ovarian Cancer trials with a reported enrollment target (83% lower).
The record links to 1 condition, with Ovarian Cancer appearing as the primary indexed condition, and to 1 intervention - of which flutamide is the first listed.
NCT00699907 reports a single indexed study location in Arizona.
Frequently Asked Questions
What is clinical trial NCT00699907 about?
NCT00699907 is a clinical study titled "Effect of Flutamide on Biomarkers in Blood and Tissue Samples From Patients at High Risk of Ovarian Cancer". Studying samples of blood and tissue in the laboratory from patients with a high risk of developing ovarian cancer may help doctors identify and learn more about biomarkers related to cancer. We hypothesized that (i) preclinical biologic evidence exists for the role of androgens in ovarian cancer de...
What is the current status of trial NCT00699907?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 127 participants. The study started on 2005-01. Estimated completion is 2014-11.
What conditions does trial NCT00699907 study?
This clinical trial studies the following conditions: Ovarian Cancer.
What interventions are being tested in trial NCT00699907?
The interventions under investigation include: flutamide (DRUG).
Who is sponsoring clinical trial NCT00699907?
This trial is sponsored by University of Arizona, which has 349 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00699907 being conducted?
This trial has 1 study location across Arizona. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00699907's enrollment target sits among peer trials
127 130th of 322 higher than 193 of 322 other Ovarian Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Ovarian Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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