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NCT03940196 · ClinicalTrials.gov registry record · Phase 3

Effect of Tumor Treating Fields (TTFields, 200 kHz) Concomitant With Weekly Paclitaxel for the Treatment of Recurrent Ovarian Cancer (ENGOT-ov50 / GOG-3029 / INNOVATE-3)

A Phase 3 study of Ovarian Cancer, sponsored by NovoCure.

Completed
Registry status
Phase 3
Development phase
540
Enrollment target
20
Study locations

NCT03940196: Completed Phase 3 study of Ovarian Cancer, sponsored by NovoCure.

NCT03940196 is a Phase 3 study of Ovarian Cancer that has completed, run by NovoCure. The registered enrollment target is 540 participants, below the 727-participant average among 322 other Ovarian Cancer trials with a reported enrollment target (26% lower). The trial reports 20 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03940196, a Phase 3 study of Ovarian Cancer, has completed, sponsored by NovoCure.

COMPLETED
Registry status
Phase 3
Development phase
540 participants
Enrollment target
20
Study locations

Study Summary

The study is a prospective, randomized controlled phase III trial aimed to test the efficacy and safety of Tumor Treating Fields (TTFields) concomitant with weekly paclitaxel for the treatment of recurrent ovarian cancer . The device is an experimental, portable, battery operated device for chronic administration of alternating electric fields (termed TTFields or TTF) to the region of the malignant tumor, by means of surface, insulated electrode arrays.

Conditions Studied

Interventions

  • DRUG Paclitaxel
  • DEVICE NovoTTF-100L(O)

Study Locations (20)

Colorado

  • Rocky Mountain Cancer Centers - Aurora
  • University of Colorado Denver - Aurora
  • Rocky Mountain Cancer Centers - Boulder
  • Rocky Mountain Cancer Centers - Colorado Springs
  • Rocky Mountain Cancer Centers - Denver
  • Rocky Mountain Cancer Centers - Denver
  • Rocky Mountain Cancer Centers - Lakewood
  • Rocky Mountain Cancer Centers - Littleton
  • Rocky Mountain Cancer Centers - Lone Tree
  • Rocky Mountain Cancer Centers - Longmont
  • Rocky Mountain Cancer Centers - Parker
  • Rocky Mountain Cancer Centers - Pueblo
  • Rocky Mountain Cancer Centers - Thornton

California

  • University of California - La Jolla
  • Hoag Memorial Hospital Presbyterian - Newport Beach
  • California Pacific Medical Center- Pacific Campus - San Francisco
  • Olive View - UCLA Medical Center - Sylmar

Arizona

  • Arizona Oncology- Biltmore Cancer Center - Phoenix
  • Arizona Oncology - Tucson

Florida

  • Broward Health Medical Center - Fort Lauderdale

Trial Details

FieldValue
Enrollment Target 540 participants
Start Date 2019-03-22
Est. Completion 2023-05-18
Phase Phase 3
NovoCure

11 total trials

What the finished NCT03940196 record still lists

NCT03940196 is an interventional study that assigns participants to a tested intervention. The registered 540 participants enrollment target is mid-sized for trials with a published cap, below the 727-participant average among 322 other Ovarian Cancer trials with a reported enrollment target (26% lower).

The record links to 1 condition, with Ovarian Cancer appearing as the primary indexed condition, and to 2 interventions - of which Paclitaxel is the first listed.

NCT03940196 names 20 study sites across 4 states, led by Colorado, California, Arizona.

Frequently Asked Questions

What is clinical trial NCT03940196 about?

NCT03940196 is a clinical study titled "Effect of Tumor Treating Fields (TTFields, 200 kHz) Concomitant With Weekly Paclitaxel for the Treatment of Recurrent Ovarian Cancer (ENGOT-ov50 / GOG-3029 / INNOVATE-3)". The study is a prospective, randomized controlled phase III trial aimed to test the efficacy and safety of Tumor Treating Fields (TTFields) concomitant with weekly paclitaxel for the treatment of recurrent ovarian cancer . The device is an experimental, portable, battery operated device for chronic ...

What is the current status of trial NCT03940196?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 540 participants. The study started on 2019-03-22. Estimated completion is 2023-05-18.

What conditions does trial NCT03940196 study?

This clinical trial studies the following conditions: Ovarian Cancer.

What interventions are being tested in trial NCT03940196?

The interventions under investigation include: Paclitaxel (DRUG), NovoTTF-100L(O) (DEVICE).

Who is sponsoring clinical trial NCT03940196?

This trial is sponsored by NovoCure, which has 11 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03940196 being conducted?

This trial has 20 study locations across Arizona, California, Colorado, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Ovarian Cancer

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT03940196's enrollment target sits among peer trials

540 43rd of 322 higher than 280 of 322 other Ovarian Cancer trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Ovarian Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03940196, the US trial registry maintained by the National Library of Medicine. NCT03940196 (mid enrollment · wide site footprint · completed) retrieved and formatted by PlainTrial, see methodology.