Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

COMPLETED Phase 1

Study of Cabiralizumab in Combination With Nivolumab in Patients With Selected Advanced Cancers

NCT02526017 · View on ClinicalTrials.gov ↗

Study Summary

Phase 1a/1b does-escalation study of cabiralizumab alone and with nivolumab in advanced solid tumors.

Interventions

  • BIOLOGICAL Nivolumab
  • BIOLOGICAL Cabiralizumab

Study Locations (20)

California

  • Moores UC San Diego Cancer Center — La Jolla
  • Norris Comprehensive Cancer Center, University of Southern California — Los Angeles
  • Cedars-Sinai Medical Center, Samuel Oschin Comprehensive Cancer Center — Los Angeles
  • UC Davis Comprehensive Cancer Center — Sacramento
  • University of California, San Francisco — San Francisco
  • Sarcoma Oncology Research Center — Santa Monica
  • UCLA Hematology/Oncology- Santa Monica — Santa Monica

Florida

  • Mount Sinai Comprehensive Cancer Center — Miami Beach
  • H. Lee Moffitt Cancer Center and Research Institute — Tampa

Illinois

  • Rush University Medical Center — Chicago
  • University of Chicago Medical Center — Chicago

Michigan

  • Karmanos Cancer Institute — Detroit
  • Henry Ford Hospital — Detroit

Arizona

  • Scottsdale Healthcare Hospitals DBA Honor Health — Scottsdale

Georgia

  • Emory University Hospital — Atlanta

Indiana

  • Indiana University Health Hospital — Indianapolis

Iowa

  • University of Iowa Hospitals and Clinics — Iowa City

Trial Details

FieldValue
Enrollment Target 313 participants
Start Date 2015-09-08
Est. Completion 2019-11-18
Phase Phase 1

Sponsor

Five Prime Therapeutics

4 total trials

Interested in This Trial?

Always speak with your doctor before enrolling in a clinical trial.

Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT02526017

The ClinicalTrials.gov registry entry for NCT02526017 describes a study currently listed as completed. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 313 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Five Prime Therapeutics, which has 4 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 7 conditions, with Ovarian Cancer appearing as the primary indexed condition, and to 2 interventions — of which Nivolumab is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT02526017 reports 20 study locations spanning 11 distinct geographic areas — top geographies include California, Florida, Illinois. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT02526017 about?

NCT02526017 is a clinical study titled "Study of Cabiralizumab in Combination With Nivolumab in Patients With Selected Advanced Cancers". Phase 1a/1b does-escalation study of cabiralizumab alone and with nivolumab in advanced solid tumors.

What is the current status of trial NCT02526017?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 313 participants. The study started on 2015-09-08. Estimated completion is 2019-11-18.

What conditions does trial NCT02526017 study?

This clinical trial studies the following conditions: Ovarian Cancer, Pancreatic Cancer, Head and Neck Cancer, Non-small Cell Lung Cancer, Advanced Solid Tumors. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT02526017?

The interventions under investigation include: Nivolumab (BIOLOGICAL), Cabiralizumab (BIOLOGICAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT02526017?

This trial is sponsored by Five Prime Therapeutics, which has 4 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT02526017 being conducted?

This trial has 20 study locations across Arizona, California, Florida, Georgia, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial