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NCT00608452 · ClinicalTrials.gov registry record

Prevalence+Significance of Paraneoplastic Autoantibodies in Many Cancers

A clinical trial of Breast Cancer and Lung Cancer, sponsored by Memorial Sloan Kettering Cancer Center.

Completed
Registry status
121
Enrollment target
1
Study location

NCT00608452: Completed study of Breast Cancer and Lung Cancer, sponsored by Memorial Sloan Kettering Cancer Center.

NCT00608452 is a study of Breast Cancer and Lung Cancer that has completed, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 121 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00608452, a study of Breast Cancer and Lung Cancer, has completed, sponsored by Memorial Sloan Kettering Cancer Center.

COMPLETED
Registry status
121 participants
Enrollment target
1
Study location

Study Summary

You may have a type of cancer associated with "antineuronal antibodies" in your blood. Antibodies are substances made by the immune system. They are used by the body to fight infections and other diseases. Antineuronal antibodies are antibodies that react with nerve cells but they also react with some tumors. We believe that the immune system makes these antibodies to fight the cancer. In some patients with these antibodies, the tumor is smaller than in patients who have no antibodies. Sometimes, with a very strong antibody test, patients may develop neurologic problems such as weakness, numbness or memory loss. One purpose of this study is to determine if a patient with cancer and a positive antineuronal antibody blood test has a smaller tumor and responds better to treatment than a patient with cancer and a negative test. Another purpose of this study is to determine whether patients with a positive antibody test develop neurologic problems such as weakness, numbness or memory loss. We will measure your blood for several different kinds of antibodies in addition to antineuronal antibodies to determine if the presence of antibodies predicts "prognosis", i.e. smaller tumor and better response to treatment, or predicts the development of neurologic problems. No tissue samples are required for this study. However, if tissue or sputum is obtained by your oncologist for diagnostic purposes, we will ask your doctors or the pathology department to provide us with samples of these specimens. This will not involve any additional surgery or discomfort to you.

Interventions

  • OTHER Symptom Assessment Scale

Study Locations (1)

New York

  • Memorial Sloan Kettering Cancer Center - New York

Trial Details

FieldValue
Enrollment Target 121 participants
Start Date 1995-07
Est. Completion 2009-11
Memorial Sloan Kettering Cancer Center

1,884 total trials

What the finished NCT00608452 record still lists

NCT00608452 is an observational study that tracks outcomes without assigning an intervention. The registered 121 participants enrollment target is mid-sized for trials with a published cap, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (96% lower).

The record links to 5 conditions, with Breast Cancer appearing as the primary indexed condition, and to 1 intervention - of which Symptom Assessment Scale is the first listed.

NCT00608452 reports a single indexed study location in New York.

Frequently Asked Questions

What is clinical trial NCT00608452 about?

NCT00608452 is a clinical study titled "Prevalence+Significance of Paraneoplastic Autoantibodies in Many Cancers". You may have a type of cancer associated with "antineuronal antibodies" in your blood. Antibodies are substances made by the immune system. They are used by the body to fight infections and other diseases. Antineuronal antibodies are antibodies that react with nerve cells but they also react with s...

What is the current status of trial NCT00608452?

This trial is currently completed. The enrollment target is 121 participants. The study started on 1995-07. Estimated completion is 2009-11.

What conditions does trial NCT00608452 study?

This clinical trial studies the following conditions: Breast Cancer, Lung Cancer, Ovarian Cancer, Neuroblastoma, Hodgkin's Disease.

What interventions are being tested in trial NCT00608452?

The interventions under investigation include: Symptom Assessment Scale (OTHER).

Who is sponsoring clinical trial NCT00608452?

This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00608452 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Breast Cancer

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00608452's enrollment target sits among peer trials

121 506th of 1224 higher than 716 of 1,224 other Breast Cancer trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Breast Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00608452, the US trial registry maintained by the National Library of Medicine. NCT00608452 (mid enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.