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ClinicalTrials.gov 147 recruiting now early-phase tilt #20 of 28,707 conditions

Ovarian Cancer: early-phase trial registry

147 of 338 indexed Ovarian Cancer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #20 of 28,707 conditions by registered trial count.

338 US clinical trials · 147 currently recruiting · #20 of 28,707 conditions by registered trial count

Ovarian Cancer: 338 US clinical trials tracked, 147 recruiting.

Ovarian Cancer is the subject of 338 registered US clinical trials on ClinicalTrials.gov, 147 of them currently open to new participants. 28 are in Phase 3-4 (later-stage) and 230 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 31 of these trials.

Enrollment posture brief

Registry condition ovarian-cancer

OPEN 147 | RECR 43% | LATE 28 | EARLY 230 | RANK #20 | SPON 31

Nearest open-share peer: Cigarette Smoking (43% recruiting · 46 trials)

Ovarian Cancer (this)43%Type 2 Diabetes36.6%Lymphoma26.7%Diabetes25.1%Diabetes Mellitus, Type 217.9%
Open-enrollment share among volume-matched conditions near Ovarian Cancer

Ovarian Cancer lists 147 open slots (43% of 338 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Ovarian Cancer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Ovarian Cancer is recruiting above its size-band peers.

    147 of 338 indexed trials (43.5%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Ovarian Cancer trials is spread across many organizations.

    Memorial Sloan Kettering Cancer Center accounts for 31 of 338 trials (9.2%). 186 distinct sponsors appear on at least one study for this condition label.

  3. Typical Ovarian Cancer enrolment sits around 86 participants.

    Median target enrolment is 86 among the 323 trials that report a genuine target (sentinel values excluded). 172 of those (53.3%) plan for fewer than 100 participants.

  4. Ovarian Cancer research is mostly interventional.

    297 interventional and 41 observational studies make up this index (87.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 1143Phase 287Phase 325Phase 43

Open and recent trials

338 total, page 6 of 7

COMPLETED Phase 1 80 participants

A Phase I Study of Infusional Chemotherapy With the P-Glycoprotein Antagonist PSC 833

National Cancer Institute (NCI)

NCT00001302

COMPLETED Phase 1 77 participants

A Clinical Study of Cobimetinib Administered in Combination With Niraparib, With or Without Atezolizumab to Patients With Advanced Platinum-sensitive Ovarian Cancer

Hoffmann-La Roche

NCT03695380

COMPLETED NA 73 participants

Writing About Experiences With Ovarian Cancer

University of Maryland, College Park

NCT02593422

COMPLETED Phase 1 73 participants

A Bioequivalence Study Between the Proposed and Current Talazoparib Capsule Formulation and Food Effect Study for the Proposed Talazoparib Capsule Formulation in Participants With Advanced Solid Tumors

Pfizer

NCT04672460

COMPLETED Phase 2 73 participants

Gleevec Study for Patients With Ovarian Cancer

M.D. Anderson Cancer Center

NCT00510653

COMPLETED Phase 1 71 participants

Study of the Safety, Pharmacokinetics and Efficacy of Tinostamustine in Patients With Advanced Solid Tumors.

Mundipharma Research Limited

NCT03345485

COMPLETED Phase 4 70 participants

A Study of LY353381 (Arzoxifene) for Patients Who Benefitted From This Drug in Other Oncology Trials and Wished to Continue Treatment

Eli Lilly and Company

NCT00190697

COMPLETED Phase 2 65 participants

Trial of Pimasertib With SAR245409 or Placebo in Ovarian Cancer

EMD Serono

NCT01936363

COMPLETED Phase 2 64 participants

Study of Oral ENMD-2076 Administered to Patients With Ovarian Cancer

CASI pharmaceuticals

NCT01104675

COMPLETED Phase 2 63 participants

CRLX101 in Combination With Bevacizumab for Recurrent Ovarian/Tubal/Peritoneal Cancer

Massachusetts General Hospital

NCT01652079

COMPLETED Phase 1 62 participants

Phase Ib Study to Determine MTD of AZD1775 Monotherapy in Patients With Locally Advanced or Metastatic Solid Tumours.

AstraZeneca

NCT02610075

COMPLETED Phase 2 60 participants

Avastin +/- Erlotinib Consolidation Chemotherapy After Carboplatin, Paclitaxel, and Avastin (CTA) Induction Therapy for Advanced Ovarian, Fallopian Tube, Primary Peritoneal Cancer & Papillary Serous or Clear Cell Mullerian Tumors

Dana-Farber Cancer Institute

NCT00520013

COMPLETED 60 participants

Elizabeth Registry for Low Grade Ovarian Cancer

M.D. Anderson Cancer Center

NCT00345709

COMPLETED Phase 2 60 participants

Combination Chemotherapy and Pegfilgrastim in Treating Patients With Previously Untreated Germ Cell Tumors

Memorial Sloan Kettering Cancer Center

NCT00470366

COMPLETED Phase 2 58 participants

Effectiveness of MORAb-003 in Women With Ovarian Cancer Who Have Relapsed After Platinum-Based Chemotherapy

Morphotek

NCT00318370

COMPLETED Phase 1 54 participants

INCB106385 Alone or in Combination With Immunotherapy in Advanced Solid Tumors

Incyte Corporation

NCT04580485

COMPLETED Phase 2 53 participants

Sunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent Sarcomas

Memorial Sloan Kettering Cancer Center

NCT00474994

COMPLETED NA 52 participants

Imaging Study on Halcyon 4.0 System for Patients Receiving Radiation Therapy

Washington University School of Medicine

NCT05427214

COMPLETED Phase 1 48 participants

A Study to Evaluate the Safety and Tolerability of Immunotherapy Combinations in Participants With Advanced Malignancies

Arcus Biosciences

NCT03629756

COMPLETED Early Phase 1 48 participants

ICG-Enabled Mapping of Ovarian Sentinel Lymph Nodes: A Feasibility Study

Memorial Sloan Kettering Cancer Center

NCT04051502

COMPLETED Phase 1 48 participants

A Study of CDX-1307, in Patients With Incurable Breast, Colorectal, Pancreatic, Ovarian or Bladder Cancer (CDX 1307-01)

Celldex Therapeutics

NCT00709462

COMPLETED Phase 2 45 participants

Combination Chemotherapy in Treating Patients With Stage III Ovarian Epithelial Cancer or Gastrointestinal Cancer

NYU Langone Health

NCT00005049

COMPLETED Phase 2 44 participants

Paclitaxel Plus Gemcitabine in Treating Patients With Refractory Metastatic Germ Cell Tumors

Eastern Cooperative Oncology Group

NCT00003518

COMPLETED Phase 1 43 participants

Combination Chemotherapy in Treating Patients With Germ Cell Tumors That Have Not Responded to Previous Cisplatin

Memorial Sloan Kettering Cancer Center

NCT00002559

COMPLETED Phase 2 42 participants

Dose Dense Paclitaxel With Pembrolizumab (MK-3475) in Platinum Resistant Ovarian Cancer

H. Lee Moffitt Cancer Center and Research Institute

NCT02440425

COMPLETED Phase 2 42 participants

Intravenous and Intraperitoneal Paclitaxel, Intraperitoneal Cisplatin, and Intravenous Bevacizumab for the Initial Treatment of Optimal Stage II or III Ovarian, Primary Peritoneal, and Fallopian Tube Cancer

Memorial Sloan Kettering Cancer Center

NCT00588237

COMPLETED Phase 2 40 participants

Ph II Study of Wkly Topotecan + Bevacizumab in Plat. Resistant/Recurrent Gyn Cancers

Benaroya Research Institute

NCT00343044

COMPLETED NA 39 participants

Yoga Practice for Breast or Ovarian Cancer Patients

Memorial Sloan Kettering Cancer Center

NCT02305498

COMPLETED Phase 1 37 participants

Dose Escalation Study of OMP-54F28 in Combination With Paclitaxel and Carboplatin in Patients With Recurrent Platinum-Sensitive Ovarian Cancer

OncoMed Pharmaceuticals

NCT02092363

COMPLETED Phase 1 36 participants

A Phase I Clinical Trial of Autologous Dendritic Cell Vaccine for Recurrent Ovarian or Primary Peritoneal Cancer

Abramson Cancer Center at Penn Medicine

NCT00683241

COMPLETED Phase 2 35 participants

Iressa (ZD1839) Plus Anastrozole (Arimidex) in Patients With Ovarian Cancer

Massachusetts General Hospital

NCT00181688

COMPLETED Phase 2 35 participants

Combination Chemotherapy in Treating Patients With Platinum-Resistant Recurrent Ovarian Cancer

University of Southern California

NCT00003449

COMPLETED Phase 1 35 participants

Ribociclib (Ribociclib (LEE-011)) With Platinum-based Chemotherapy in Recurrent Platinum Sensitive Ovarian Cancer

Ronald Buckanovich

NCT03056833

COMPLETED 34 participants

Genes Contributing to Hereditary Ovarian Cancer in Women and BRCA1/2 Wildtype Families

University of Washington

NCT03119285

COMPLETED Phase 1 34 participants

Study of Magrolimab (Hu5F9-G4) in Combination With Avelumab in Solid Tumor Participants and Checkpoint-Inhibitor-Naive Ovarian Cancer Participants Who Progress Within 6 Months of Prior Platinum Chemotherapy

Gilead Sciences

NCT03558139

COMPLETED Phase 1 32 participants

Effects of STM 434 Alone or in Combination With Liposomal Doxorubicin in Patients With Ovarian Cancer or Other Advanced Solid Tumors

Santa Maria Biotherapeutics

NCT02262455

COMPLETED Phase 2 30 participants

A Study to Evaluate ONM-100, an Intraoperative Fluorescence Imaging Agent for the Detection of Cancer

OncoNano Medicine

NCT03735680

COMPLETED Phase 2 30 participants

Gemcitabine and Docetaxel in Treating Patients With Relapsed or Refractory Ovarian Epithelial or Peritoneal Cancer

Robert Morris

NCT00227721

COMPLETED Phase 1 30 participants

Radiolabeled Monoclonal Antibody, Paclitaxel, and Interferon Alfa in Treating Patients With Recurrent Ovarian Cancer

National Cancer Institute (NCI)

NCT00002734

COMPLETED Phase 1 30 participants

Vinorelbine and XR9576 to Treat Cancer

National Cancer Institute (NCI)

NCT00001944

COMPLETED Early Phase 1 29 participants

Availability & Effect of Post-OP Ketorolac on Ovarian, Fallopian Tube or Primary Peritoneal Cancer

New Mexico Cancer Research Alliance

NCT01670799

COMPLETED Phase 2 29 participants

TPIV200/huFR-1 (A Multi-Epitope Anti-Folate Receptor Vaccine) Plus Anti-PD-L1 MEDI4736 (Durvalumab) in Patients With Platinum Resistant Ovarian Cancer

Memorial Sloan Kettering Cancer Center

NCT02764333

COMPLETED Phase 1 28 participants

Trial of Decitabine as a Sensitizer to Carboplatin in Platinum Resistant Recurrent Ovarian Cancer

Indiana University

NCT00477386

COMPLETED Phase 1 27 participants

Intraperitoneal Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Advanced Cancer of the Peritoneal Cavity

City of Hope Medical Center

NCT00825201

COMPLETED Phase 1 24 participants

Docetaxel and PTK787 in Metastatic Breast Cancer Patients and Gynecological Cancer Patients

Dana-Farber Cancer Institute

NCT00268918

COMPLETED Phase 2 24 participants

Pilot Study of Rosuvastatin and Enoxaparin Thromboprophylaxis Following Ovarian Cancer Surgery (O-STAT Study)

Beth Israel Deaconess Medical Center

NCT03532139

COMPLETED Phase 1 24 participants

Topotecan Plus Etoposide in Treating Patients With Recurrent Ovarian, Peritoneal, or Fallopian Tube Cancer

Gynecologic Oncology Group

NCT00003967

COMPLETED Phase 2 22 participants

Arsenic Trioxide in Treating Patients With Advanced Neuroblastoma or Other Childhood Solid Tumors

Memorial Sloan Kettering Cancer Center

NCT00024258

COMPLETED NA 21 participants

Evaluation of GTPase Inhibition by Post-operative Intravenous Ketorolac in Ovarian Cancer Patients

New Mexico Cancer Research Alliance

NCT02470299

COMPLETED Phase 2 21 participants

Safety Study Of Avastin And Pelvic Radiation In Women With Recurrent Gynecological Cancers

Dana-Farber Cancer Institute

NCT00545792

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Phase Distribution

PhaseTrial count
Phase 1 143
Phase 2 87
Phase 3 25
Phase 4 3

Named interventions

Most-linked intervention names on Ovarian Cancer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Bevacizumab Drug
19 trials
Paclitaxel Drug
18 trials
Carboplatin Drug
13 trials
paclitaxel Drug
12 trials
carboplatin Drug
10 trials
Cyclophosphamide Drug
10 trials
Fludarabine Drug
8 trials
Pembrolizumab Drug
8 trials

US sites by state

Facility locations filed on Ovarian Cancer trials. A trial with sites in several states counts in each.

New York 114 trials
California 105 trials
Texas 104 trials
Florida 86 trials
Massachusetts 74 trials
Pennsylvania 58 trials
Michigan 51 trials
Ohio 50 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Ovarian Cancer page

338 registered trials, 147 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Ovarian Cancer condition card totals 338 registered trials; most-linked intervention Bevacizumab; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.