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ClinicalTrials.gov 147 recruiting now early-phase tilt #20 of 28,707 conditions

Ovarian Cancer: early-phase trial registry

147 of 338 indexed Ovarian Cancer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #20 of 28,707 conditions by registered trial count.

338 US clinical trials · 147 currently recruiting · #20 of 28,707 conditions by registered trial count

Ovarian Cancer: 338 US clinical trials tracked, 147 recruiting.

Ovarian Cancer is the subject of 338 registered US clinical trials on ClinicalTrials.gov, 147 of them currently open to new participants. 28 are in Phase 3-4 (later-stage) and 230 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 31 of these trials.

Enrollment posture brief

Registry condition ovarian-cancer

OPEN 147 | RECR 43% | LATE 28 | EARLY 230 | RANK #20 | SPON 31

Nearest open-share peer: Cigarette Smoking (43% recruiting · 46 trials)

Ovarian Cancer (this)43%Type 2 Diabetes36.6%Lymphoma26.7%Diabetes25.1%Diabetes Mellitus, Type 217.9%
Open-enrollment share among volume-matched conditions near Ovarian Cancer

Ovarian Cancer lists 147 open slots (43% of 338 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Ovarian Cancer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Ovarian Cancer is recruiting above its size-band peers.

    147 of 338 indexed trials (43.5%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Ovarian Cancer trials is spread across many organizations.

    Memorial Sloan Kettering Cancer Center accounts for 31 of 338 trials (9.2%). 186 distinct sponsors appear on at least one study for this condition label.

  3. Typical Ovarian Cancer enrolment sits around 86 participants.

    Median target enrolment is 86 among the 323 trials that report a genuine target (sentinel values excluded). 172 of those (53.3%) plan for fewer than 100 participants.

  4. Ovarian Cancer research is mostly interventional.

    297 interventional and 41 observational studies make up this index (87.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 1143Phase 287Phase 325Phase 43

Open and recent trials

338 total, page 1 of 7

RECRUITING NA 65,000 participants

Transvaginal Ultrasonography as a Screening Method for Ovarian Cancer

John R van Nagell

NCT04473833

RECRUITING 25,000 participants

Avera Cancer Sequencing and Analytics Protocol (ASAP)

Avera McKennan Hospital & University Health Center

NCT05142033

RECRUITING 9,600 participants

Sample Collection for Ongoing Research and Product Evaluation Study

Natera

NCT07318051

RECRUITING NA 8,000 participants

Use of the CA 125 Algorithm for the Early Detection of Ovarian Cancer in Low Risk Women

M.D. Anderson Cancer Center

NCT00539162

RECRUITING 6,000 participants

Specimen and Data Study for Ovarian Cancer Early Detection and Prevention

Northwestern University

NCT00005095

RECRUITING 3,300 participants

Genetic & Pathological Studies of BRCA1/BRCA2: Associated Tumors & Blood Samples

Stanford University

NCT01034033

RECRUITING NA 3,209 participants

Evaluating an Evidence-Based Family History Screening Program Adapted to Increase Reach and Uptake of Screening for BRCA-Associated Cancers in Rural Public Health Clinics

Emory University

NCT06760507

RECRUITING 3,110 participants

Leveraging Methylated DNA Markers (MDMs) in the Detection of Endometrial Cancer, Ovarian Cancer, and Cervical Cancer

Mayo Clinic

NCT05051722

RECRUITING NA 3,000 participants

TUBectomy With Delayed Oophorectomy in High Risk Women to Assess the Safety of Prevention

University Medical Center Nijmegen

NCT04294927

RECRUITING 2,000 participants

UNTOLD Ovarian Cancer Unmet Needs Survey

Masonic Cancer Center, University of Minnesota

NCT07070726

RECRUITING 1,500 participants

The DETECT Study: Discovery and Evaluation of Testing for Endometrial and Ovarian Cancer in Tampons

University of Alabama at Birmingham

NCT03538665

RECRUITING 1,400 participants

EXoPERT EMERALD Clinical Study

EXoPERT

NCT07186296

RECRUITING 1,100 participants

Collection of Blood From Patients With Cancer, Other Tumors, or Tumor Predisposition Syndromes for Genetic Analysis

National Cancer Institute (NCI)

NCT01441089

RECRUITING NA 1,020 participants

Video Education With Result Dependent dIsclosure

Dana-Farber Cancer Institute

NCT05225428

RECRUITING NA 1,000 participants

Identifying Underserved Individuals inTexas With Hereditary Cancer Risk Using Mobile Mammography Units and Telegenetics.

M.D. Anderson Cancer Center

NCT05649072

RECRUITING NA 1,000 participants

Improving Nutrition and Physical Activity for Cancer Survivors (Tools To Be Fit)

University of California, San Francisco

NCT05056077

RECRUITING Phase 3 900 participants

A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer (MK-2870-021)

Merck Sharp & Dohme

NCT07318558

RECRUITING Phase 3 770 participants

A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)

Merck Sharp & Dohme

NCT06824467

RECRUITING NA 625 participants

Comprehensive Outcomes for After Cancer Health

Pack Health

NCT05349227

RECRUITING Phase 1 612 participants

A Study to Find Out How Safe REGN5668 is and How Well it Works In Adult Women When Given With Either Cemiplimab, or Cemiplimab + Fianlimab, or Ubamatamab

Regeneron Pharmaceuticals

NCT04590326

RECRUITING Phase 3 582 participants

Study of Trastuzumab Deruxtecan With Bevacizumab Versus Bevacizumab Monotherapy for First-line Maintenance in HER2-Expressing Ovarian Cancer (DESTINY-Ovarian01)

Daiichi Sankyo

NCT06819007

RECRUITING Phase 3 538 participants

Primary Cytoreductive Surgery With or Without Hyperthermic Intraperitoneal Chemotherapy (HIPEC)

The Netherlands Cancer Institute

NCT03772028

RECRUITING Phase 3 528 participants

Study to Assess the Efficacy and Safety of Rina-S Plus Standard of Care Compared to Standard of Care for Maintenance Treatment of Participants With Recurrent Platinum-sensitive Ovarian Cancer After Second-line (2L) Platinum-based Doublet Chemotherapy

Genmab

NCT07225270

RECRUITING Phase 3 520 participants

Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer

AbbVie

NCT05445778

RECRUITING Phase 1 506 participants

Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors

AstraZeneca

NCT05797168

RECRUITING Phase 3 500 participants

Phase 3 Trial Evaluating the Safety & Efficacy of IMNN-001 Administered in Combination w/ Standard NACT & Adjuvant Chemotherapy in Newly Diagnosed Patients w/ Advanced EOC, Fallopian Tube or Primary Peritoneal Cancer

Imunon

NCT06915025

RECRUITING Phase 1 490 participants

A Study of LY4101174 in Participants With Recurrent, Advanced or Metastatic Solid Tumors

Eli Lilly and Company

NCT06238479

RECRUITING NA 480 participants

A Study Evaluating the Integrative Medicine at Home (IM@HOME) Program in People With Cancer

Memorial Sloan Kettering Cancer Center

NCT05053230

RECRUITING Phase 1 470 participants

Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

SystImmune

NCT05983432

RECRUITING Phase 3 466 participants

Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

Incyte Corporation

NCT07214779

RECRUITING Phase 1 460 participants

A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies

AstraZeneca

NCT05123482

RECRUITING Phase 2 454 participants

Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)

AstraZeneca

NCT05489211

RECRUITING NA 445 participants

Developing New Educational Materials About Genetic Testing for a Diverse Group of Cancer Patients

Memorial Sloan Kettering Cancer Center

NCT04751435

RECRUITING Phase 1 442 participants

A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors

Artios Pharma

NCT04657068

RECRUITING Phase 1 420 participants

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

Eli Lilly and Company

NCT06465069

RECRUITING Phase 1 386 participants

Phase I Study of SYS6043 in Patients With Advanced/Metastatic Solid Tumors

Conjupro Biotherapeutics

NCT07424547

RECRUITING Phase 2 320 participants

18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection

National Cancer Institute (NCI)

NCT06503146

RECRUITING Phase 1 319 participants

A Study of XMT-1660 in Participants With Solid Tumors

Mersana Therapeutics

NCT05377996

RECRUITING Phase 3 310 participants

A Study of Intra-operative Imaging in Women With Ovarian Cancer

Memorial Sloan Kettering Cancer Center

NCT04878094

RECRUITING Phase 1 300 participants

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

PMV Pharmaceuticals

NCT04585750

RECRUITING Phase 2 285 participants

Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Neoantigens in People With Metastatic Cancer

National Cancer Institute (NCI)

NCT03412877

RECRUITING Phase 1 282 participants

Phase 1, Safety and Tolerability Study of XmAb541 in Advanced Solid Tumors

Xencor

NCT06276491

RECRUITING Phase 1 280 participants

Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors

SystImmune

NCT06293898

RECRUITING Phase 2 270 participants

Relacorilant in Combination With Different Treatment Regimens in Patients With Gynecological Cancers

Corcept Therapeutics

NCT06906341

RECRUITING Phase 1 263 participants

A Study of CUSP06 in Patients With Platinum-Refractory/Resistant Ovarian Cancer and Other Advanced Solid Tumors

OnCusp Therapeutics

NCT06234423

RECRUITING Phase 1 258 participants

A Study to Examine the Safety of Different Doses of BG-68501 Given to Participants With Advanced-Stage Tumors

BeiGene

NCT06257264

RECRUITING Phase 1 250 participants

FiH Study to Investigate Safety, PK and Efficacy of the NaPi2b ADC TUB-040 in Patients With PROC or r/r Adenocarcinoma NSCLC

Tubulis

NCT06303505

RECRUITING 245 participants

The SENTRY Study: Testing Whether Changes in Platelet RNA Enhance the Early Diagnosis of Ovarian Cancer

University of Utah

NCT06665945

RECRUITING NA 240 participants

REVITALIZE: RCT to Reduce Fatigue in Adults With Ovarian Cancer on PARP Inhibitors

Dana-Farber Cancer Institute

NCT06710548

RECRUITING Phase 1 226 participants

Study Evaluating the Safety and Efficacy of HWK-007, a PTK7-directed Antibody Drug Conjugate in Participants With Advanced Solid Tumors

Whitehawk Therapeutics

NCT07444814

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Phase Distribution

PhaseTrial count
Phase 1 143
Phase 2 87
Phase 3 25
Phase 4 3

Named interventions

Most-linked intervention names on Ovarian Cancer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Bevacizumab Drug
19 trials
Paclitaxel Drug
18 trials
Carboplatin Drug
13 trials
paclitaxel Drug
12 trials
carboplatin Drug
10 trials
Cyclophosphamide Drug
10 trials
Fludarabine Drug
8 trials
Pembrolizumab Drug
8 trials

US sites by state

Facility locations filed on Ovarian Cancer trials. A trial with sites in several states counts in each.

New York 114 trials
California 105 trials
Texas 104 trials
Florida 86 trials
Massachusetts 74 trials
Pennsylvania 58 trials
Michigan 51 trials
Ohio 50 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Ovarian Cancer page

338 registered trials, 147 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Ovarian Cancer condition card totals 338 registered trials; most-linked intervention Bevacizumab; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.