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NCT04294927 · ClinicalTrials.gov registry record · NA
TUBectomy With Delayed Oophorectomy in High Risk Women to Assess the Safety of Prevention
A NA study of Ovarian Cancer and BRCA1 Gene Mutation, sponsored by University Medical Center Nijmegen.
- Recruiting
- Registry status
- NA
- Development phase
- 3,000
- Enrollment target
- 20
- Study locations
NCT04294927: Recruiting NA study of Ovarian Cancer and BRCA1 Gene Mutation, sponsored by University Medical Center Nijmegen.
NCT04294927 is a NA study of Ovarian Cancer and BRCA1 Gene Mutation that is actively recruiting participants, run by University Medical Center Nijmegen. The registered enrollment target is 3,000 participants, above the 719-participant average among 322 other Ovarian Cancer trials with a reported enrollment target (317% higher). The trial reports 20 study locations across 10 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04294927, a NA study of Ovarian Cancer and BRCA1 Gene Mutation, is actively recruiting participants, sponsored by University Medical Center Nijmegen.
- RECRUITING
- Registry status
- NA
- Development phase
- 3,000 participants
- Enrollment target
- 20
- Study locations
Study Summary
The aim of the project is to evaluate the risk-reducing salpingectomy with delayed oophorectomy as an alternative for risk-reducing salpingo-oophorectomy in high risk women with respect to ovarian cancer incidence.
Primary Outcome
High grade serous (ovarian) cancer incidence
Conditions Studied
Interventions
- PROCEDURE Risk-reducing salpingectomy with delayed oophorectomy
- PROCEDURE Risk-reducing salpingo-oophorectomy
Study Locations (20)
Other
- Monash Health - Melbourne
- Peter MacCallum Centre - Melbourne
- Royal Womens Hospital - Melbourne
- Hopital Universitaire Bruxelles - Brussels
- Universitair Ziekenhuis Leuven - Leuven
Victoria
- Frances Perry House - Melbourne
- Mercy Hospital - Melbourne
- Epworth Hospital - Richmon
- Western Health - St Albans
Queensland
- St Andrew War Memorial Hospital - Brisbane
- Royal Brisbane Hospital - Brisbane
- Greenslopes Private Hospital - Brisbane
New South Wales
- Chris O'Brien Lifehouse - Sydney
- Westmead hospital - Sydney
Massachusetts
- Dana Farber Cancer Institute - Boston
Minnesota
- Mayo Clinic - Rochester
Texas
- MD Anderson Cancer Centre - Houston
Washington
- University of Washington - Seattle
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3,000 participants |
| Start Date | 2020-03-01 |
| Est. Completion | 2040-02-17 |
| Phase | NA |
What NCT04294927 shows while recruiting
NCT04294927 is an interventional study that assigns participants to a tested intervention. Its 3,000 participants enrollment target places it among the larger protocols in the corpus, above the 719-participant average among 322 other Ovarian Cancer trials with a reported enrollment target (317% higher).
The record links to 6 conditions, with Ovarian Cancer appearing as the primary indexed condition, and to 2 interventions - of which Risk-reducing salpingectomy with delayed oophorectomy is the first listed.
NCT04294927 names 20 study sites across 10 states, led by Other, Victoria, Queensland.
Frequently Asked Questions
What is clinical trial NCT04294927 about?
NCT04294927 is a clinical study titled "TUBectomy With Delayed Oophorectomy in High Risk Women to Assess the Safety of Prevention". The aim of the project is to evaluate the risk-reducing salpingectomy with delayed oophorectomy as an alternative for risk-reducing salpingo-oophorectomy in high risk women with respect to ovarian cancer incidence.
What is the current status of trial NCT04294927?
This trial is currently recruiting. It is a NA study. The enrollment target is 3,000 participants. The study started on 2020-03-01. Estimated completion is 2040-02-17.
What conditions does trial NCT04294927 study?
This clinical trial studies the following conditions: Ovarian Cancer, BRCA1 Gene Mutation, BRCA2 Gene Mutation, BRIP1 Gene Mutation, RAD51C Gene Mutation.
What interventions are being tested in trial NCT04294927?
The interventions under investigation include: Risk-reducing salpingectomy with delayed oophorectomy (PROCEDURE), Risk-reducing salpingo-oophorectomy (PROCEDURE).
Who is sponsoring clinical trial NCT04294927?
This trial is sponsored by University Medical Center Nijmegen, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04294927 being conducted?
This trial has 20 study locations across Massachusetts, Minnesota, Texas, Washington, New South Wales. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT04294927's enrollment target sits among peer trials
3,000 12th of 322 higher than 311 of 322 other Ovarian Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Ovarian Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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