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TUBectomy With Delayed Oophorectomy in High Risk Women to Assess the Safety of Prevention
NCT04294927 · View on ClinicalTrials.gov ↗
Study Summary
The aim of the project is to evaluate the risk-reducing salpingectomy with delayed oophorectomy as an alternative for risk-reducing salpingo-oophorectomy in high risk women with respect to ovarian cancer incidence.
Conditions Studied
Interventions
- PROCEDURE Risk-reducing salpingectomy with delayed oophorectomy
- PROCEDURE Risk-reducing salpingo-oophorectomy
Study Locations (20)
Other
- Monash Health — Melbourne
- Peter MacCallum Centre — Melbourne
- Royal Womens Hospital — Melbourne
- Hopital Universitaire Bruxelles — Brussels
- Universitair Ziekenhuis Leuven — Leuven
Victoria
- Frances Perry House — Melbourne
- Mercy Hospital — Melbourne
- Epworth Hospital — Richmon
- Western Health — St Albans
Queensland
- St Andrew War Memorial Hospital — Brisbane
- Royal Brisbane Hospital — Brisbane
- Greenslopes Private Hospital — Brisbane
New South Wales
- Chris O'Brien Lifehouse — Sydney
- Westmead hospital — Sydney
Massachusetts
- Dana Farber Cancer Institute — Boston
Minnesota
- Mayo Clinic — Rochester
Texas
- MD Anderson Cancer Centre — Houston
Washington
- University of Washington — Seattle
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3,000 participants |
| Start Date | 2020-03-01 |
| Est. Completion | 2040-02-17 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04294927
The ClinicalTrials.gov registry entry for NCT04294927 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 3,000 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University Medical Center Nijmegen, which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 6 conditions, with Ovarian Cancer appearing as the primary indexed condition, and to 2 interventions — of which Risk-reducing salpingectomy with delayed oophorectomy is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT04294927 reports 20 study locations spanning 10 distinct geographic areas — top geographies include Other, Victoria, Queensland. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT04294927 about?
NCT04294927 is a clinical study titled "TUBectomy With Delayed Oophorectomy in High Risk Women to Assess the Safety of Prevention". The aim of the project is to evaluate the risk-reducing salpingectomy with delayed oophorectomy as an alternative for risk-reducing salpingo-oophorectomy in high risk women with respect to ovarian cancer incidence.
What is the current status of trial NCT04294927?
This trial is currently recruiting. It is a NA study. The enrollment target is 3,000 participants. The study started on 2020-03-01. Estimated completion is 2040-02-17.
What conditions does trial NCT04294927 study?
This clinical trial studies the following conditions: Ovarian Cancer, BRCA1 Gene Mutation, BRCA2 Gene Mutation, BRIP1 Gene Mutation, RAD51C Gene Mutation. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT04294927?
The interventions under investigation include: Risk-reducing salpingectomy with delayed oophorectomy (PROCEDURE), Risk-reducing salpingo-oophorectomy (PROCEDURE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT04294927?
This trial is sponsored by University Medical Center Nijmegen, which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT04294927 being conducted?
This trial has 20 study locations across Massachusetts, Minnesota, Texas, Washington, New South Wales. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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