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Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression
NCT07214779 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of this study is to evaluate INCB123667 versus investigator's choice of chemotherapy in participants with platinum-resistant ovarian cancer with cyclin E1 overexpression.
Conditions Studied
Interventions
- DRUG INCB123667
- DRUG Investigator's choice of chemotherapy
Study Locations (20)
North Carolina
- Levine Cancer Center — Charlotte
- Novant Presbyterian Hospital — Charlotte
- Atrium Health Wake Forest Baptist — Winston-Salem
California
- City of Hope Medical Center — Duarte
- Valkyrie Clinical Trials — Los Angeles
Oregon
- Oncology Associates of Oregon, P.C. — Eugene
- Providence Cancer Institute Franz Clinic — Portland
Pennsylvania
- University of Pittsburgh Cancer Institute Cancer Services — Pittsburgh
- Wellspan Gynecologic Oncology — York
Georgia
- Georgia Cancer Center — Augusta
Illinois
- Northshore University Health System-Evanston Hospital — Evanston
Louisiana
- Women'S Cancer Care — Covington
Maine
- Maine Center For Cancer Medicine — Scarborough
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 466 participants |
| Start Date | 2025-12-09 |
| Est. Completion | 2029-05-14 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07214779
The ClinicalTrials.gov registry entry for NCT07214779 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 466 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Incyte Corporation, which has 163 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Ovarian Cancer appearing as the primary indexed condition, and to 2 interventions — of which INCB123667 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT07214779 reports 20 study locations spanning 15 distinct geographic areas — top geographies include North Carolina, California, Oregon. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT07214779 about?
NCT07214779 is a clinical study titled "Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression". The purpose of this study is to evaluate INCB123667 versus investigator's choice of chemotherapy in participants with platinum-resistant ovarian cancer with cyclin E1 overexpression.
What is the current status of trial NCT07214779?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 466 participants. The study started on 2025-12-09. Estimated completion is 2029-05-14.
What conditions does trial NCT07214779 study?
This clinical trial studies the following conditions: Ovarian Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT07214779?
The interventions under investigation include: INCB123667 (DRUG), Investigator's choice of chemotherapy (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT07214779?
This trial is sponsored by Incyte Corporation, which has 163 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT07214779 being conducted?
This trial has 20 study locations across California, Georgia, Illinois, Louisiana, Maine. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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