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ClinicalTrials.gov 147 recruiting now early-phase tilt #20 of 28,707 conditions

Ovarian Cancer: early-phase trial registry

147 of 338 indexed Ovarian Cancer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #20 of 28,707 conditions by registered trial count.

338 US clinical trials · 147 currently recruiting · #20 of 28,707 conditions by registered trial count

Ovarian Cancer: 338 US clinical trials tracked, 147 recruiting.

Ovarian Cancer is the subject of 338 registered US clinical trials on ClinicalTrials.gov, 147 of them currently open to new participants. 28 are in Phase 3-4 (later-stage) and 230 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 31 of these trials.

Enrollment posture brief

Registry condition ovarian-cancer

OPEN 147 | RECR 43% | LATE 28 | EARLY 230 | RANK #20 | SPON 31

Nearest open-share peer: Cigarette Smoking (43% recruiting · 46 trials)

Ovarian Cancer (this)43%Type 2 Diabetes36.6%Lymphoma26.7%Diabetes25.1%Diabetes Mellitus, Type 217.9%
Open-enrollment share among volume-matched conditions near Ovarian Cancer

Ovarian Cancer lists 147 open slots (43% of 338 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Ovarian Cancer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Ovarian Cancer is recruiting above its size-band peers.

    147 of 338 indexed trials (43.5%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Ovarian Cancer trials is spread across many organizations.

    Memorial Sloan Kettering Cancer Center accounts for 31 of 338 trials (9.2%). 186 distinct sponsors appear on at least one study for this condition label.

  3. Typical Ovarian Cancer enrolment sits around 86 participants.

    Median target enrolment is 86 among the 323 trials that report a genuine target (sentinel values excluded). 172 of those (53.3%) plan for fewer than 100 participants.

  4. Ovarian Cancer research is mostly interventional.

    297 interventional and 41 observational studies make up this index (87.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 1143Phase 287Phase 325Phase 43

Open and recent trials

338 total, page 2 of 7

RECRUITING Phase 1 220 participants

Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors

MOMA Therapeutics

NCT06545942

RECRUITING Phase 2 220 participants

Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer

Regeneron Pharmaceuticals

NCT06787612

RECRUITING Phase 1 216 participants

A Study of PARG Inhibitor IDE161 in Participants With Advanced Solid Tumors

IDEAYA Biosciences

NCT05787587

RECRUITING Phase 1 210 participants

Autologous T-cells Genetically Engineered to Express Receptors Reactive Against KRAS Mutations in Conjunction With a Vaccine Directed Against These Antigens in Participants With Metastatic Cancer

National Cancer Institute (NCI)

NCT06253520

RECRUITING Phase 1 207 participants

A Study to Assess Adverse Events, Change in Disease Activity and How Intravenous (IV) ABBV901 Moves Through the Body Alone or in Combination With Bevacizumab in Adult Participants With Ovarian Cancer

AbbVie

NCT07278336

RECRUITING Phase 1 205 participants

A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors

NiKang Therapeutics

NCT07029399

RECRUITING Phase 1 205 participants

A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations

Terremoto Biosciences

NCT07109726

RECRUITING NA 200 participants

Trial of Exercise and Lifestyle for Women With Ovarian and Endometrial Cancer

Yale University

NCT05761561

RECRUITING 200 participants

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

A2 Biotherapeutics

NCT04981119

RECRUITING Phase 2 200 participants

A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors

Jazz Pharmaceuticals

NCT06695845

RECRUITING Phase 2 180 participants

RESOLVE: Abemaciclib + Letrozole +/- Metformin, Zotatifin, or Gedatolisib in Endometrial or Low-Grade Serous Ovarian Cancer

Dana-Farber Cancer Institute

NCT03675893

RECRUITING Phase 1 176 participants

BI-1808 as a Single Agent and With Pembrolizumab (KEYTRUDA® ) in Treatment of Advanced Malignancies(Keynote-D20)

BioInvent International AB

NCT04752826

RECRUITING Phase 3 170 participants

Gleolan for Visualization of Newly Diagnosed or Recurrent Ovarian Cancer (OVA-302)

NX Development

NCT05804370

RECRUITING Phase 2 160 participants

A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

Incyte Corporation

NCT07023627

RECRUITING Phase 1 150 participants

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

NiKang Therapeutics

NCT06586957

RECRUITING Phase 1 150 participants

A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors

Normunity AccelCo

NCT07182149

RECRUITING Phase 1 150 participants

Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer

Incyclix Bio

NCT05735080

RECRUITING Phase 1 150 participants

A First-in-Human Study of SON-DP in Participants With Relapsed/Refractory Intolerant to Standard of Care Therapies for Advanced/Metastatic Solid Tumors

Qurgen

NCT05989724

RECRUITING Phase 1 145 participants

A Phase 1 Study of LNCB74 in Advanced Solid Tumors

NextCure

NCT06774963

RECRUITING Phase 1 124 participants

Administering Peripheral Blood Lymphocytes Transduced With a CD70-Binding Chimeric Antigen Receptor to People With CD70 Expressing Cancers

National Cancer Institute (NCI)

NCT02830724

RECRUITING Phase 1 122 participants

A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies

AtlasMedx, Incorporated

NCT04503265

RECRUITING Phase 1 120 participants

A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies

858 Therapeutics

NCT06395519

RECRUITING Phase 2 114 participants

A Study of Radspherin® in Patients With Primary Advanced Epithelial Cancer, With Peritoneal Metastasis That Are Homologous Recombination Proficient Scheduled to Undergo Neoadjuvant Chemotherapy and Interval Debulking Surgery

Oncoinvent Solutions AS

NCT06504147

RECRUITING Phase 1 113 participants

FT836 With or Without Chemotherapy and/or Monoclonal Antibodies, in Participants With Advanced Solid Tumors

Fate Therapeutics

NCT07216105

RECRUITING NA 112 participants

Pilot Randomized Controlled Trial of a Collaborative Agenda-setting Intervention (CASI) for Patients With Ovarian Cancer

Dana-Farber Cancer Institute

NCT06543537

RECRUITING Phase 1 112 participants

Lead-212 PSV359 Therapy for Patients With Solid Tumors

Perspective Therapeutics

NCT06710756

RECRUITING 105 participants

ESPERANZA: External Control Arm Study for T-DXd for Patients With HER2 IHC3+ Solid Tumors

AstraZeneca

NCT06973161

RECRUITING Phase 1 100 participants

Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma

Nammi Therapeutics

NCT06582017

RECRUITING Early Phase 1 100 participants

Using Aspirin to Improve Immunological Features of Ovarian Tumors

H. Lee Moffitt Cancer Center and Research Institute

NCT05080946

RECRUITING 100 participants

Laboratory Study of Cancer & Immune Cells in Ascites Fluid of Ovarian Cancer Patients to Test Alternative Therapies

New Mexico Cancer Research Alliance

NCT03943316

RECRUITING Phase 1 100 participants

A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors

Apollo Therapeutics

NCT06399757

RECRUITING NA 100 participants

Risk Reducing Salpingectomy With Delayed Oophorectomy as an Alternative to Risk- Reducing Salpingo-oophorectomy in High Risk-Women to Assess the Safety of Prevention - US Cohort Study

M.D. Anderson Cancer Center

NCT05287451

RECRUITING Phase 1 96 participants

A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas

Dren Bio

NCT06999187

RECRUITING Phase 1 92 participants

AOH1996 for the Treatment of Refractory Solid Tumors

City of Hope Medical Center

NCT05227326

RECRUITING Phase 1 90 participants

First-in-Human Study of ATX-295, an Oral Inhibitor of KIF18A, in Patients With Advanced or Metastatic Solid Tumors, Including Ovarian Cancer

Accent Therapeutics

NCT06799065

RECRUITING Phase 2 90 participants

A Study of Isoquercetin in People With Ovarian Cancer

Memorial Sloan Kettering Cancer Center

NCT07303894

RECRUITING Phase 1 90 participants

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

Clasp Therapeutics

NCT06778863

RECRUITING Phase 1 90 participants

TT-10 (PORT-6) and TT-4 (PORT-7) as Single Agents and in Combination in Subjects With Advanced Selected Solid Tumors

Portage Biotech

NCT04969315

RECRUITING Phase 1 90 participants

ROCKIF Trial: Re-sensitization of Carboplatin-resistant Ovarian Cancer With Kinase Inhibition of FAK

Michael McHale

NCT03287271

RECRUITING Phase 1 90 participants

First in Human Study of TORL-1-23 in Participants With Advanced Cancer

TORL Biotherapeutics

NCT05103683

RECRUITING Phase 2 86 participants

Tart Cherry Juice as a Dietary Supplement for the Prevention of Paclitaxel-Induced Neuropathy

University of California, Davis

NCT06268665

RECRUITING Phase 2 86 participants

Study of Acute Normovolemic Hemodilution (ANH) in People With Ovarian Cancer Who Are Having Cytoreductive Surgery

Memorial Sloan Kettering Cancer Center

NCT06290193

RECRUITING Phase 1 78 participants

IDOV-Immune for Advanced Solid Tumors

ViroMissile

NCT06910657

RECRUITING NA 70 participants

ASk Questions in GYnecologic Oncology (ASQ-GYO)

Ira Winer

NCT06339827

RECRUITING Phase 2 70 participants

Study of Carboplatin and Mirvetuximab Soravtansine in First-Line Treatment of Patients Receiving Neoadjuvant Chemotherapy With Advanced-Stage Ovarian, Fallopian Tube or Primary Peritoneal Cancer

University of Alabama at Birmingham

NCT04606914

RECRUITING Phase 4 70 participants

Study Evaluating Safety, Tolerability, and Metabolism of Niraparib

University of Miami

NCT06412120

RECRUITING NA 70 participants

Hugo™ Robotic-Assisted Surgery (RAS) System in Gynecological Subjects (Embrace Gynecology)

Medtronic - MITG

NCT07120945

RECRUITING NA 70 participants

Spanish Decision Tool for Ovarian Cancer Maintenance Therapy

M.D. Anderson Cancer Center

NCT06036810

RECRUITING Phase 1 70 participants

SLV-154 Treatment of Metastatic Solid Tumors

Solve Therapeutics

NCT06771219

RECRUITING Phase 1 67 participants

Trial of Single Protein Encapsulated Doxorubicin, SPEDOX-6 in Advanced Malignancies

University of California, Irvine

NCT07064018

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Phase Distribution

PhaseTrial count
Phase 1 143
Phase 2 87
Phase 3 25
Phase 4 3

Named interventions

Most-linked intervention names on Ovarian Cancer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Bevacizumab Drug
19 trials
Paclitaxel Drug
18 trials
Carboplatin Drug
13 trials
paclitaxel Drug
12 trials
carboplatin Drug
10 trials
Cyclophosphamide Drug
10 trials
Fludarabine Drug
8 trials
Pembrolizumab Drug
8 trials

US sites by state

Facility locations filed on Ovarian Cancer trials. A trial with sites in several states counts in each.

New York 114 trials
California 105 trials
Texas 104 trials
Florida 86 trials
Massachusetts 74 trials
Pennsylvania 58 trials
Michigan 51 trials
Ohio 50 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Ovarian Cancer page

338 registered trials, 147 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Ovarian Cancer condition card totals 338 registered trials; most-linked intervention Bevacizumab; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.