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NCT06760507 · ClinicalTrials.gov registry record · NA

Evaluating an Evidence-Based Family History Screening Program Adapted to Increase Reach and Uptake of Screening for BRCA-Associated Cancers in Rural Public Health Clinics

A NA study of Breast Cancer and Ovarian Cancer, sponsored by Emory University.

Recruiting
Registry status
NA
Development phase
3,209
Enrollment target
1
Study location

NCT06760507: Recruiting NA study of Breast Cancer and Ovarian Cancer, sponsored by Emory University.

NCT06760507 is a NA study of Breast Cancer and Ovarian Cancer that is actively recruiting participants, run by Emory University. The registered enrollment target is 3,209 participants, above the 2,801-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (15% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06760507, a NA study of Breast Cancer and Ovarian Cancer, is actively recruiting participants, sponsored by Emory University.

RECRUITING
Registry status
NA
Development phase
3,209 participants
Enrollment target
1
Study location

Study Summary

This clinical trial adapts and evaluates the effectiveness of a family history screening program (GA CORE) for increasing uptake of genetic screening for BRCA-associated cancers in women who have received care in rural public health clinics in Southwest Georgia. Brief and low-cost family history-based screening assessments to identify families at high risk for BRCA-associated cancers have been endorsed by national guidelines and public health organizations. Georgia is among the few states to have implemented statewide family history screening for BRCA-associated cancers. Despite its potential, current clinic-based approaches that identify at-risk women are not sustainable and show limited reach. Additionally, uptake of follow-up cancer screening is sub-optimal and solely focuses on women screened as high genetic risk. This trial will adapt the existing family history screening program and then evaluate it's effectiveness for increasing the number and diversity of women who receive a history assessment and subsequent access to risk-based services such as genetic counseling and testing.

Primary Outcome

Defined as the number and proportion of the women older than 25 years served by the clinics who complete screening tool. Screening uptake rate at each site will be calculated with a 95% confidence interval. Comparison between arms will be carried out using a mixed-effects logistic regression model.

Interventions

  • OTHER Adapted Family History Screening Program

Study Locations (1)

Georgia

  • Emory University Hospital/Winship Cancer Institute - Atlanta

Trial Details

FieldValue
Enrollment Target 3,209 participants
Start Date 2025-02-01
Est. Completion 2028-06-30
Phase NA
Emory University

1,208 total trials

What NCT06760507 shows while recruiting

NCT06760507 is an interventional study that assigns participants to a tested intervention. Its 3,209 participants enrollment target places it among the larger protocols in the corpus, above the 2,801-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (15% higher).

The record links to 2 conditions, with Breast Cancer appearing as the primary indexed condition, and to 1 intervention - of which Adapted Family History Screening Program is the first listed.

NCT06760507 reports a single indexed study location in Georgia.

Frequently Asked Questions

What is clinical trial NCT06760507 about?

NCT06760507 is a clinical study titled "Evaluating an Evidence-Based Family History Screening Program Adapted to Increase Reach and Uptake of Screening for BRCA-Associated Cancers in Rural Public Health Clinics". This clinical trial adapts and evaluates the effectiveness of a family history screening program (GA CORE) for increasing uptake of genetic screening for BRCA-associated cancers in women who have received care in rural public health clinics in Southwest Georgia. Brief and low-cost family history-bas...

What is the current status of trial NCT06760507?

This trial is currently recruiting. It is a NA study. The enrollment target is 3,209 participants. The study started on 2025-02-01. Estimated completion is 2028-06-30.

What conditions does trial NCT06760507 study?

This clinical trial studies the following conditions: Breast Cancer, Ovarian Cancer.

What interventions are being tested in trial NCT06760507?

The interventions under investigation include: Adapted Family History Screening Program (OTHER).

Who is sponsoring clinical trial NCT06760507?

This trial is sponsored by Emory University, which has 1,208 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06760507 being conducted?

This trial has 1 study location across Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Breast Cancer

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06760507's enrollment target sits among peer trials

3,209 48th of 1224 higher than 1,177 of 1,224 other Breast Cancer trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Breast Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06760507, the US trial registry maintained by the National Library of Medicine. NCT06760507 (large enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.