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RECRUITING Phase 3

Phase 3 Trial Evaluating the Safety & Efficacy of IMNN-001 Administered in Combination w/ Standard NACT & Adjuvant Chemotherapy in Newly Diagnosed Patients w/ Advanced EOC, Fallopian Tube or Primary Peritoneal Cancer

NCT06915025 · View on ClinicalTrials.gov ↗

Study Summary

This is a randomized, adaptive, open label, multicenter trial to evaluate the safety and efficacy of intraperitoneal (IP) IMNN-001 plus chemotherapy compared to chemotherapy alone.

Interventions

  • DRUG Carboplatin
  • DRUG Olaparib
  • DRUG Paclitaxel
  • DRUG Niraparib
  • DRUG IMNN-001 (IL-12 Plasmid Formulated with PEG-PEI-Cholesterol Lipopolymer)

Study Locations (7)

Florida

  • Advent Health — Orlando

Missouri

  • Washington University School of Medicine in St. Louis — St Louis

Oregon

  • Providence Cancer Institute — Portland

South Dakota

  • Sanford Health — Sioux Falls

Tennessee

  • Erlanger Health — Chattanooga

Washington

  • Providence Sacred Heart Medical Center & Children's Hospital — Spokane

Wisconsin

  • Froedtert and The Medical College of Wisconsin — Milwaukee

Trial Details

FieldValue
Enrollment Target 500 participants
Start Date 2025-07-09
Est. Completion 2032-10-31
Phase Phase 3

Sponsor

Imunon

6 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06915025

The ClinicalTrials.gov registry entry for NCT06915025 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 500 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Imunon, which has 6 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 4 conditions, with Ovarian Cancer appearing as the primary indexed condition, and to 5 interventions — of which Carboplatin is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06915025 reports 7 study locations spanning 7 distinct geographic areas — top geographies include Florida, Missouri, Oregon. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06915025 about?

NCT06915025 is a clinical study titled "Phase 3 Trial Evaluating the Safety & Efficacy of IMNN-001 Administered in Combination w/ Standard NACT & Adjuvant Chemotherapy in Newly Diagnosed Patients w/ Advanced EOC, Fallopian Tube or Primary Peritoneal Cancer". This is a randomized, adaptive, open label, multicenter trial to evaluate the safety and efficacy of intraperitoneal (IP) IMNN-001 plus chemotherapy compared to chemotherapy alone.

What is the current status of trial NCT06915025?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 500 participants. The study started on 2025-07-09. Estimated completion is 2032-10-31.

What conditions does trial NCT06915025 study?

This clinical trial studies the following conditions: Ovarian Cancer, Fallopian Tube Cancer, Epithelial Ovarian Cancer, Primary Peritoneal Carcinoma. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06915025?

The interventions under investigation include: Carboplatin (DRUG), Olaparib (DRUG), Paclitaxel (DRUG), Niraparib (DRUG), IMNN-001 (IL-12 Plasmid Formulated with PEG-PEI-Cholesterol Lipopolymer) (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06915025?

This trial is sponsored by Imunon, which has 6 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06915025 being conducted?

This trial has 7 study locations across Florida, Missouri, Oregon, South Dakota, Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial