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NCT04473833 · ClinicalTrials.gov registry record · NA
Transvaginal Ultrasonography as a Screening Method for Ovarian Cancer
A NA study of Ovarian Cancer, sponsored by John R van Nagell.
- Recruiting
- Registry status
- NA
- Development phase
- 65,000
- Enrollment target
- 1
- Study location
NCT04473833: Recruiting NA study of Ovarian Cancer, sponsored by John R van Nagell.
NCT04473833 is a NA study of Ovarian Cancer that is actively recruiting participants, run by John R van Nagell. The registered enrollment target is 65,000 participants, above the 527-participant average among 322 other Ovarian Cancer trials with a reported enrollment target (12234% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04473833, a NA study of Ovarian Cancer, is actively recruiting participants, sponsored by John R van Nagell.
- RECRUITING
- Registry status
- NA
- Development phase
- 65,000 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a large, prospective, single-arm cohort study of transvaginal ultrasonographic screening for ovarian cancer in intermediate to high-risk women from Kentucky. Detection of ovarian malignancy often occurs subsequent to the initial transvaginal sonography (TVS) screen; therefore, it is important to offer continued screening to study participants based on our published algorithm. Screening will be available to participants for as long as they elect to receive it. The primary study endpoints are to determine if prospective serial transvaginal ultrasonography can decrease the false-positive (FP) percentage and improve the positive predictive value (PPV) as suggested by retrospective analysis without compromising the detection of true positives or promote the occurrence of false negatives.
Primary Outcome
Measure the false-positive (FP) rate generated by the ovarian screening algorithm.
Conditions Studied
Interventions
- PROCEDURE Serial Transvaginal Ultrasonography
Study Locations (1)
Kentucky
- Markey Cancer Center - Lexington
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 65,000 participants |
| Start Date | 1988-12-19 |
| Est. Completion | 2026-12-31 |
| Phase | NA |
What NCT04473833 shows while recruiting
NCT04473833 is an interventional study that assigns participants to a tested intervention. Its 65,000 participants enrollment target places it among the larger protocols in the corpus, above the 527-participant average among 322 other Ovarian Cancer trials with a reported enrollment target (12234% higher).
The record links to 1 condition, with Ovarian Cancer appearing as the primary indexed condition, and to 1 intervention - of which Serial Transvaginal Ultrasonography is the first listed.
NCT04473833 reports a single indexed study location in Kentucky.
Frequently Asked Questions
What is clinical trial NCT04473833 about?
NCT04473833 is a clinical study titled "Transvaginal Ultrasonography as a Screening Method for Ovarian Cancer". This is a large, prospective, single-arm cohort study of transvaginal ultrasonographic screening for ovarian cancer in intermediate to high-risk women from Kentucky. Detection of ovarian malignancy often occurs subsequent to the initial transvaginal sonography (TVS) screen; therefore, it is importan...
What is the current status of trial NCT04473833?
This trial is currently recruiting. It is a NA study. The enrollment target is 65,000 participants. The study started on 1988-12-19. Estimated completion is 2026-12-31.
What conditions does trial NCT04473833 study?
This clinical trial studies the following conditions: Ovarian Cancer.
What interventions are being tested in trial NCT04473833?
The interventions under investigation include: Serial Transvaginal Ultrasonography (PROCEDURE).
Who is sponsoring clinical trial NCT04473833?
This trial is sponsored by John R van Nagell, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04473833 being conducted?
This trial has 1 study location across Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Ovarian Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04473833's enrollment target sits among peer trials
65,000 1st of 322 higher than 322 of 322 other Ovarian Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Ovarian Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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