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Hypertension: full-pipeline trial registry
152 of 472 indexed Hypertension trials are currently recruiting.
Corpus placement: #8 of 28,707 conditions by registered trial count.
472 US clinical trials · 152 currently recruiting · #8 of 28,707 conditions by registered trial count
Hypertension: 472 US clinical trials tracked, 152 recruiting.
Hypertension is the subject of 472 registered US clinical trials on ClinicalTrials.gov, 152 of them currently open to new participants. 65 are in Phase 3-4 (later-stage) and 64 in Phase 1-2 (earlier-stage). The most active sponsor is Johns Hopkins University, running 15 of these trials.
Enrollment posture brief
Registry condition hypertension
OPEN 152 | RECR 32% | LATE 65 | EARLY 64 | RANK #8 | SPON 15
Volume-matched condition peers
Nearest open-share peer: Leukemia, Myeloid, Acute (32% recruiting · 31 trials)
Hypertension lists 152 open slots (32% of 472 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Hypertension on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Hypertension is recruiting below its size-band peers.
152 of 472 indexed trials (32.2%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Hypertension trials is spread across many organizations.
Johns Hopkins University accounts for 15 of 472 trials (3.2%). 195 distinct sponsors appear on at least one study for this condition label.
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Typical Hypertension enrolment sits around 168 participants.
Median target enrolment is 168 among the 471 trials that report a genuine target (sentinel values excluded). 170 of those (36.1%) plan for fewer than 100 participants.
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Hypertension research is mostly interventional.
407 interventional and 65 observational studies make up this index (86.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
472 total, page 5 of 10
Renal Metabolism in Salt-sensitive Human Blood Pressure
Medical College of Wisconsin
NCT05369416
CHW Intervention to Improve Nutrition Security of Patients With Hypertension
Massachusetts General Hospital
NCT06358417
Wild Blueberries and Cardiovascular Health in Middle-aged/Older Men and Postmenopausal Women
Colorado State University
NCT04530916
Vitamin D and Immune Mechanisms of Hypertension in Type 2 Diabetics
Washington University School of Medicine
NCT03348280
Improving Pain Management Via Spinal Cord Stimulation and Blood Pressure Reduction
University of Kansas Medical Center
NCT04676399
Exercise, Hypertension, and Gut Dysbiosis in African Americans
North Carolina Agriculture & Technical State University
NCT03897777
Telehealth Treatment of Veterans With Alcohol Misuse at Risk for Cardiovascular Disease
VA Office of Research and Development
NCT04838457
TMS for PTSD and Blood Pressure
Lifespan
NCT05512143
Plant-based Diet for Kidney Transplant Recipients
George Washington University
NCT06186843
Adiposity and Endothelin Receptor Function
Augusta University
NCT03583866
A Study to Evaluate Renal Fibrosis Using MRI Techniques
Mayo Clinic
NCT04508049
Monitoring Blood Pressure at Home
University of Alabama at Birmingham
NCT06247111
Enhancing Mental and Physical Health of Women Veterans
VA Office of Research and Development
NCT05050266
The Influence of Tai Chi Practice on Blood Pressure and Brain Health Among Older Adults with Hypertension (ACTION)
University of Connecticut
NCT04384263
Role of Sympathetic Activity and Splanchnic Capacitance in Hypertension
Vanderbilt University
NCT02425566
Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Propranolol/Carvedilol Versus Atenolol/Bisoprolol/Sotalol
Brigham and Women's Hospital
NCT05794997
Multi-Method Health System Quality Improvement Intervention to Reduce Hypertension Disparities
Johns Hopkins University
NCT01566864
Social Norms, Messengers, and Processing Fluency to Increase Hypertension Medication Adherence
Brigham and Women's Hospital
NCT06066541
Replication of the ONTARGET Antihypertensive Trial in Healthcare Claims Data
Brigham and Women's Hospital
NCT04354350
Effect of Reminders on Adherence
University of Pennsylvania
NCT02411006
Pediatric Blood Pressure Clinical Decision Support Tool (PedsBP CDS)
HealthPartners Institute
NCT05126082
Improving Service Delivery Through Access Points
US Department of Veterans Affairs
NCT00012623
Evaluating the Navajo Community Outreach and Patient Empowerment (COPE) Program
Brigham and Women's Hospital
NCT03326206
ACEI or ARB and COVID-19 Severity and Mortality in US Veterans
University of Utah
NCT04467931
Hypertension Management Using Remote Patient Monitoring: Study 2
Northwestern University
NCT04764318
Action to Control Cardiovascular Risk in Diabetes (ACCORD)
National Heart, Lung, and Blood Institute (NHLBI)
NCT00000620
Personalized Patient Data and Behavioral Nudges to Improve Adherence to Chronic Cardiovascular Medications
University of Colorado, Denver
NCT03973931
Systolic Blood Pressure Intervention Trial
National Heart, Lung, and Blood Institute (NHLBI)
NCT01206062
Cooking for Health Optimization With Patients
Tulane University
NCT03443635
Improving Diabetes in Primary Care (IMPACT)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00108927
Clinical Decision Support for Medication Management and Adherence
Duke University
NCT00979225
Adherence and Intensification of Medications (AIM) Implementation Study
US Department of Veterans Affairs
NCT00495794
Improving Quality With Outpatient Decision Support
Agency for Healthcare Research and Quality (AHRQ)
NCT00225628
Clinical Study to Evaluate the Efficacy and Safety of Aliskiren Alone and in Combination With Hydrochlorothiazide in Patients With Essential Hypertension.
Novartis
NCT00219024
Minority Health Genomics and Translational Research Bio-Repository Database (MH-GRID)-2.0
National Heart, Lung, and Blood Institute (NHLBI)
NCT02290392
Monitoring and Testing of Blood Pressure in Postpartum Women
Wake Forest University Health Sciences
NCT05236725
Hypertension Management Using Remote Patient Monitoring
Northwestern University
NCT05562921
Efficacy and Safety of GMRx2 Compared to Dual Combinations for the Treatment of Hypertension
George Medicines PTY Limited
NCT04518293
Telmisartan (Micardis) and Ramipril (Altace) - Factorial Design Study for the Treatment of Hypertension
Boehringer Ingelheim
NCT00281593
Efficacy and Safety of LCZ696A in Patients With Essential Hypertension
Novartis Pharmaceuticals
NCT00549770
Improving Practice Patterns for the Treatment of Hypertension
US Department of Veterans Affairs
NCT00265044
Levels of Inflammatory Markers in the Treatment of Stroke-An SPS3 Ancillary Study
Columbia University
NCT00579306
Community Partnership to Examine Racial and Ethnic Differences in Health Care for Hypertension and Diabetes
Harvard Medical School (HMS and HSDM)
NCT00379652
Aliskiren and Valsartan vs Valsartan Alone in Patients With Stage II Systolic Hypertension and Type II Diabetes Mellitus
Novartis
NCT00927394
Study of a Holistic Health Program for United Methodist Clergy
Duke Clergy Health Initiative
NCT01564719
Efficacy and Safety of Lorundrostat in Subjects With Uncontrolled and Resistant Hypertension
Mineralys Therapeutics
NCT06153693
TROPHY - Candesartan Cilexetil Long-term Hypertension Prevention Trial
AstraZeneca
NCT00227318
Asian American Partnerships in Research and Empowerment (AsPIRE)
NYU Langone Health
NCT03100812
Improving Albuminuria Screening Compliance Using a Smartphone Urinalysis Kit
Geisinger Clinic
NCT03470701
Efficacy and Safety Comparison of Azilsartan Medoxomil to Valsartan in Participants With Essential Hypertension
Takeda
NCT00591578
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 39 |
| Phase 2 | 25 |
| Phase 3 | 37 |
| Phase 4 | 28 |
Top Sponsors
Named interventions
Most-linked intervention names on Hypertension records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Hypertension trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Hypertension page
472 registered trials, 152 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 152 Hypertension trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Johns Hopkins University sponsors the most Hypertension trials on record, review their full trial history before evaluating a specific study. See Johns Hopkins University's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Hypertension condition card totals 472 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.