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Hypertension: full-pipeline trial registry
152 of 472 indexed Hypertension trials are currently recruiting.
Corpus placement: #8 of 28,707 conditions by registered trial count.
472 US clinical trials · 152 currently recruiting · #8 of 28,707 conditions by registered trial count
Hypertension: 472 US clinical trials tracked, 152 recruiting.
Hypertension is the subject of 472 registered US clinical trials on ClinicalTrials.gov, 152 of them currently open to new participants. 65 are in Phase 3-4 (later-stage) and 64 in Phase 1-2 (earlier-stage). The most active sponsor is Johns Hopkins University, running 15 of these trials.
Enrollment posture brief
Registry condition hypertension
OPEN 152 | RECR 32% | LATE 65 | EARLY 64 | RANK #8 | SPON 15
Volume-matched condition peers
Nearest open-share peer: Leukemia, Myeloid, Acute (32% recruiting · 31 trials)
Hypertension lists 152 open slots (32% of 472 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Hypertension on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Hypertension is recruiting below its size-band peers.
152 of 472 indexed trials (32.2%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Hypertension trials is spread across many organizations.
Johns Hopkins University accounts for 15 of 472 trials (3.2%). 195 distinct sponsors appear on at least one study for this condition label.
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Typical Hypertension enrolment sits around 168 participants.
Median target enrolment is 168 among the 471 trials that report a genuine target (sentinel values excluded). 170 of those (36.1%) plan for fewer than 100 participants.
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Hypertension research is mostly interventional.
407 interventional and 65 observational studies make up this index (86.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
472 total, page 4 of 10
Sleep Promotion and Pediatric Hypertension
Children's Hospital of Philadelphia
NCT06642246
Positron Emission Tomography (PET) Imaging of Cholesterol Trafficking: Clinical Evaluation of [18F]FNP-59 in Normal Human Subjects (Group 1)
Benjamin Viglianti
NCT04532489
Vitamin D and Omega-3 Hypertension Trial (VITAL Hypertension)
Brigham and Women's Hospital
NCT01653678
Implementing a Home Blood Pressure Monitoring Program in Primary Care
Columbia University
NCT05885997
Electronic Alert to Improve Testing For Primary Aldosteronism in Patients With Hypertension
Brigham and Women's Hospital
NCT05925569
Bogalusa Heart Study
Tulane University
NCT00005129
Cardiovascular Health Study (CHS)
National Heart, Lung, and Blood Institute (NHLBI)
NCT00005133
Team-Based Home Blood Pressure Monitoring
University of Rochester
NCT05488795
The Jackson Heart Study of Cardiovascular Disease Among African Americans
National Heart, Lung, and Blood Institute (NHLBI)
NCT00005485
Patient Education Video to Reduce OTC NSAIDs
Carilion Clinic
NCT06575205
Implementation of Multifaceted Patient-Centered Treatment Strategies for Intensive Blood Pressure Control in Minimize Cognitive Decline
Tulane University
NCT04797403
SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN
Medtronic Vascular
NCT05198674
Community Mobilization for Improved Clean Cookstove Uptake, Household Air Pollution Reduction, and Hypertension Prevention
NYU Langone Health
NCT05048147
Open-Label Extension (OLE) Study to Assess Safety, Efficacy, and Tolerability of Lorundrostat in Subjects With Hypertension
Mineralys Therapeutics
NCT05968430
The PIVOT Trial: Project on EHR-Integrated Lifestyle Interventions for Adults Aged Fifty and Older
University of Illinois at Chicago
NCT05654142
Remote Monitoring and Virtual Collaborative Care For Hypertension Control to Prevent Cognitive Decline Phase II
University of Kansas Medical Center
NCT05138601
Developing a Learning COmmunity to Increase eNgagemeNt and Enrollment in Cardiovascular Clinical Trials (CONNECT)
Johns Hopkins University
NCT06347484
Integration of Hypertension Management Into HIV Care in Nigeria
NYU Langone Health
NCT04704336
A Randomized Trial of Behaviorally Designed Gamification and Social Incentives to Increase Physical Activity Among Overweight and Obese Veterans
VA Office of Research and Development
NCT05554601
Virtual Diabetes Group Visits Across Health Systems
University of Chicago
NCT06094491
Dissemination of the Cardiovascular Risk Service
Korey Kennelty
NCT03660631
Multi-ethnic Multi-level Strategies and Behavioral Economics to Eliminate Hypertension Disparities in Los Angeles County
University of California, Los Angeles
NCT06359691
Equity in Prevention and Progression of Hypertension by Addressing Barriers to Nutrition and Physical activitY
University of Alabama at Birmingham
NCT05367544
Arlington Longitudinal Optimal Healthy Aging Study (ALOHA)
Marymount University
NCT07180147
Skills-Based Educational Strategies for Reduction of Vascular Events in Orange County
University of California, Irvine
NCT05641519
Home Blood Pressure Telemonitoring LINKED With Community Health Workers to Improve Blood Pressure
Johns Hopkins University
NCT05180045
mGlide RCT: A Clinical Glide Path To Close the Guideline-to-Practice Gap In HTN Management
University of Minnesota
NCT03612271
Randomized Clinical Trial to Improve Mobility After Hospitalization
University of Pennsylvania
NCT05736484
Linkage, Empowerment, and Access to Prevent Hypertension
Wayne State University
NCT05061108
Endothelin Receptor Function and Acute Stress
Augusta University
NCT02116335
Onco-primary Care Networking to Support TEAM-based Care
Duke University
NCT04258813
TARGET BP I Clinical Trial
Ablative Solutions
NCT02910414
CALM- 2 - Controlling and Lowering Blood Pressure With the MobiusHD™
Vascular Dynamics
NCT03179800
MR Antagonist and LSD1
Brigham and Women's Hospital
NCT04840342
RADIANCE Continued Access Protocol
ReCor Medical
NCT05017935
A Study of the ReCor Medical Paradise System in Clinical Hypertension
ReCor Medical
NCT02649426
The RADIANCE II Pivotal Study: A Study of the ReCor Medical Paradise System in Stage II Hypertension
ReCor Medical
NCT03614260
A Study to Investigate Tonlamarsen for the Treatment of Adults With Uncontrolled Hypertension (KARDINAL)
Kardigan
NCT06864104
Using mHealth to Improve Adherence and Reduce Blood Pressure in Individuals With Hypertension and Mood Disorders
Case Western Reserve University
NCT04675593
Groceries for Black Residents of Boston to Stop Hypertension Among Adults With Treated Hypertension
Beth Israel Deaconess Medical Center
NCT05393232
Groceries for Black Residents of Boston to Stop Hypertension Among Adults Without Treated Hypertension
Beth Israel Deaconess Medical Center
NCT05121337
Hypertension Chronobiome
University of Pennsylvania
NCT03598894
Breathing Training for Improving Cardiovascular Health in Older Adults With Sleep Apnea
University of Arizona
NCT04932447
Caveolin-1 and Vascular Dysfunction
Brigham and Women's Hospital
NCT01426529
HELP-HY: Health Education and sLeep Program in HYpertension
Mayo Clinic
NCT03255746
A Study of Cardiovascular Disparities in the Greater Mankato Somali Community to Prevent Hypertension
Mayo Clinic
NCT05873153
Peer Comparison Feedback to Providers to Improve Hypertension Control
University of Pennsylvania
NCT05160012
Team-based Care to Improve Hypertension
New York University
NCT05413252
Stress and Blood Pressure Management for Caregivers
Ohio State University
NCT05734638
Epidural Spinal Cord Stimulation for Hypertension in Patients With Neuropathic Pain
University of Kansas Medical Center
NCT04598035
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 39 |
| Phase 2 | 25 |
| Phase 3 | 37 |
| Phase 4 | 28 |
Top Sponsors
Named interventions
Most-linked intervention names on Hypertension records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Hypertension trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Hypertension page
472 registered trials, 152 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 152 Hypertension trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Johns Hopkins University sponsors the most Hypertension trials on record, review their full trial history before evaluating a specific study. See Johns Hopkins University's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Hypertension condition card totals 472 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.