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Alabama: below-average open trial sites
1,209 of 4,168 in-state trials are recruiting (29%); below the 37% national average by 8 percentage points.
According to ClinicalTrials.gov-derived indexes, Alabama sits in the upper half of US states by in-state trial count (#16 of 52 states by registered in-state trial count).
Alabama: 4,168 US clinical trials with in-state sites, 1,209 recruiting.
Alabama has 4,168 registered US clinical trials with a study site in-state, 1,209 of them currently recruiting (below the 37% national average by 8 percentage points). 1,447 of these trials are in Phase 3 (late-stage) and 1,011 in Phase 2. The most frequently studied condition in Alabama is HIV Infections, with 83 linked trials.
Mid-pack research density
Alabama sits in the upper half of the state corpus, so volume is meaningful but not hub-scale. Use condition and sponsor rollups below to see what drives the in-state mix.
Below-average open enrollment
Alabama still shows 1,209 recruiting of 4,168 in-state trials (29% open), but below the 37% national average by 8 percentage points, so archived statuses weigh heavier than the national baseline.
- 29%
- open (below national share)
- 1,209
- still recruiting despite cool share
- 1,011
- Phase 2 rows in this footprint
- 83
- top: HIV Infections
Recruiting share is below the 37% national average by 8 percentage points. Counts include every study with at least one recorded site in the state. Registry reference only, not medical advice.
Alabama vs all states by indexed in-state trial count
Where this state's ClinicalTrials.gov site count sits among every state with at least one listed trial (coverage density, not care quality)
4,168 Top 31% more indexed trials than 69% of 52 states
States, banded by indexed in-state trial count
Each bar is a band; taller bars hold more states. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov · 2026-08-08
Key findings
What ClinicalTrials.gov does not surface for Alabama on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Alabama open-enrollment share sits below the national baseline.
1,209 of 4,168 in-state trials (29%) are recruiting, against 37% nationally (-8 percentage points). Counts include every study with at least one recorded site in the state.
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Birmingham dominates Alabama's trial geography.
Birmingham lists 3,118 of 4,168 in-state trials (74.8%) across 929 named facilities. Cities need five or more listed trials to appear here; locations are as filed by sponsors.
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HIV Infections is the most-studied condition in Alabama.
83 of 4,168 in-state trials (2%) list HIV Infections. That is a local concentration figure, not a national disease ranking.
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One sponsor accounts for a large share of Alabama trials.
University of Alabama at Birmingham appears on 432 of 4,168 in-state trials (10.4%). Sponsor identity is as filed on ClinicalTrials.gov.
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1,981 Alabama trials carry a completed status.
1,981 of 4,168 (47.5%) are completed. The open share above is the remainder that still lists recruiting.
By Status
| Status | Trial count |
|---|---|
| Completed | 1,981 |
| Recruiting | 1,209 |
| Active | 978 |
By Phase
| Phase | Trial count |
|---|---|
| Phase 3 | 1,447 |
| Phase 2 | 1,011 |
| NA | 662 |
| Phase 1 | 390 |
| Phase 4 | 183 |
| Early Phase 1 | 21 |
Top Conditions
Top Sponsors
Where trials run in Alabama
Birmingham carries 3,118 of Alabama's 4,168 indexed trials (75%) across 929 named sites, ahead of Mobile at 611. 8 cities clear five listed trials, together naming 1,611 distinct sites.
| City | Trials | Listed sites |
|---|---|---|
| Birmingham | 3,118 | 929 |
| Mobile | 611 | 258 |
| Huntsville | 373 | 177 |
| Dothan | 141 | 79 |
| Anniston | 128 | 33 |
| Montgomery | 103 | 59 |
| Tuscaloosa | 93 | 44 |
| Daphne | 65 | 32 |
Distinct trials and named sites per city, as filed with ClinicalTrials.gov; cities under five trials omitted. Vintage 2026-08-08.
Open-share low
Alabama open-enrollment share is 29% (p20 of states with sites; national baseline 37%).
Alabama: open share sits in the low tercile of states
Geography is concentrated: Birmingham alone accounts for 75% of Alabama's indexed trials (3,118 of 4,168), with Mobile a distant second at 611.
Phase mix: 1,447 Phase 3 vs 1,011 Phase 2 (balanced across stages).
Top condition: HIV Infections (83 trials); top sponsor University of Alabama at Birmingham (432).
high-volume · low-open figures (4,168 trials · 29% open) describe registry geography under the open-share low read, not clinic capacity or protocol fit. Confirm status on ClinicalTrials.gov before acting.
States near Alabama on open-enrollment share
Cross-state peers under the open-share low read (high-volume · low-open), not the same-state browse list.
Similar high-volume hubs (± open share)
- Missouri · 4,116 trials · 33% recruiting
- Minnesota · 4,506 trials · 36% recruiting
- Michigan · 4,790 trials · 34% recruiting
- Connecticut · 3,531 trials · 32% recruiting
- Tennessee · 3,520 trials · 33% recruiting
Similar low-open peers (± trial volume)
- Indiana · 29% recruiting · 3,113 trials
- New Mexico · 29% recruiting · 579 trials
- Kansas · 29% recruiting · 2,080 trials
- Nebraska · 29% recruiting · 1,301 trials
- Arkansas · 28% recruiting · 2,376 trials