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NCT03897777 · ClinicalTrials.gov registry record · NA
Exercise, Hypertension, and Gut Dysbiosis in African Americans
A NA study of Hypertension, sponsored by North Carolina Agriculture & Technical State University.
- Active
- Registry status
- NA
- Development phase
- 36
- Enrollment target
- 1
- Study location
NCT03897777: Active NA study of Hypertension, sponsored by North Carolina Agriculture & Technical State University.
NCT03897777 is a NA study of Hypertension that is active but no longer recruiting, run by North Carolina Agriculture & Technical State University. The registered enrollment target is 36 participants, below the 3,507-participant average among 470 other Hypertension trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03897777, a NA study of Hypertension, is active but no longer recruiting, sponsored by North Carolina Agriculture & Technical State University.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 36 participants
- Enrollment target
- 1
- Study location
Study Summary
African Americans have the greatest burden of endothelial dysfunction and hypertension. Recently, gut microbial dysbiosis (a term that describes a poorly diverse gut microbial profile and lower short-chain fatty acid (SCFA) production) has been linked to hypertension and may be involved in the pathogenesis of hypertension in African Americans. African Americans have been reported to have lower gut SCFA and SCFA can reduce blood pressure. Exercise reduces blood pressure and improves gut dysbiosis (increases SCFA) and likely couples' improvements in gut microbial health and vascular function to reduce blood pressure. Thus, the goals of this research are to fill a critical void concerning the interaction of gut dysbiosis, hypertension, and utilizing exercise to identify gut microbial adaptations that accompany a reduction in blood pressure. The short-term implications of this work will advance the clinical communities understanding of the relationship between dysbiosis and the pathogenesis of hypertension in African Americans, while long term implications will promote identifying adaptable gut microbes associated with vascular health to aid in amending treatment strategies for hypertension.
Conditions Studied
Interventions
- BEHAVIORAL Exercise Training effect on Hypertension and Gut Dysbiosis
Study Locations (1)
North Carolina
- North Carolina A&T State University - Greensboro
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2019-06-01 |
| Est. Completion | 2026-06 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03897777
The ClinicalTrials.gov registry entry for NCT03897777 describes a study currently listed as active not recruiting, categorized as NA. The registered enrollment target is 36 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 3,507-participant average among 470 other Hypertension trials with a reported enrollment target (99% lower). The listed sponsor is North Carolina Agriculture & Technical State University, which has 6 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Hypertension appearing as the primary indexed condition, and to 1 intervention - of which Exercise Training effect on Hypertension and Gut Dysbiosis is the first listed.
NCT03897777 reports 1 study location spanning 1 distinct geographic area - top geographies include North Carolina.
Frequently Asked Questions
What is clinical trial NCT03897777 about?
NCT03897777 is a clinical study titled "Exercise, Hypertension, and Gut Dysbiosis in African Americans". African Americans have the greatest burden of endothelial dysfunction and hypertension. Recently, gut microbial dysbiosis (a term that describes a poorly diverse gut microbial profile and lower short-chain fatty acid (SCFA) production) has been linked to hypertension and may be involved in the patho...
What is the current status of trial NCT03897777?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 36 participants. The study started on 2019-06-01. Estimated completion is 2026-06.
What conditions does trial NCT03897777 study?
This clinical trial studies the following conditions: Hypertension.
What interventions are being tested in trial NCT03897777?
The interventions under investigation include: Exercise Training effect on Hypertension and Gut Dysbiosis (BEHAVIORAL).
Who is sponsoring clinical trial NCT03897777?
This trial is sponsored by North Carolina Agriculture & Technical State University, which has 6 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03897777 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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