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NCT05369416 · ClinicalTrials.gov registry record · NA
Renal Metabolism in Salt-sensitive Human Blood Pressure
A NA study of Hypertension, sponsored by Medical College of Wisconsin.
- Active
- Registry status
- NA
- Development phase
- 70
- Enrollment target
- 1
- Study location
NCT05369416: Active NA study of Hypertension, sponsored by Medical College of Wisconsin.
NCT05369416 is a NA study of Hypertension that is active but no longer recruiting, run by Medical College of Wisconsin. The registered enrollment target is 70 participants, below the 3,507-participant average among 470 other Hypertension trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05369416, a NA study of Hypertension, is active but no longer recruiting, sponsored by Medical College of Wisconsin.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 70 participants
- Enrollment target
- 1
- Study location
Study Summary
Salt sensitive hypertension is a significant health problem worldwide and a primary modifiable risk factor for renal, cardiovascular, and cerebrovascular diseases. Yet, the underlying mechanisms remain poorly understood. The proposed study determines how renal oxygenation and substrate metabolism differs between individuals with and without salt sensitivity, with the ultimate goal of identifying mechanisms, diagnostic criteria, and treatment strategies for salt sensitive hypertension.
Primary Outcome
70 subjects (\~50% women, \~50% AA) will be recruited and salt sensitivity will be determined (defined as ≥8 mmHg decrease in systolic BP on a low Na+ diet). BOLD-MRI and MRI with arterial spin labeling (MRI-ASL) will be performed to assess renal regional tissue oxygenation and perfusion at baseline and after high and low Na+ diets.
Conditions Studied
Interventions
- OTHER Low sodium diet
- OTHER high sodium diet
Study Locations (1)
Wisconsin
- Medical College of Wisconsin /Froedtert Hospital - Milwaukee
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 2021-11-01 |
| Est. Completion | 2030-01-30 |
| Phase | NA |
What the registry record for NCT05369416 still lists
NCT05369416 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 70 participants, a relatively small participant target, below the 3,507-participant average among 470 other Hypertension trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Hypertension appearing as the primary indexed condition, and to 2 interventions - of which Low sodium diet is the first listed.
NCT05369416 reports a single indexed study location in Wisconsin.
Frequently Asked Questions
What is clinical trial NCT05369416 about?
NCT05369416 is a clinical study titled "Renal Metabolism in Salt-sensitive Human Blood Pressure". Salt sensitive hypertension is a significant health problem worldwide and a primary modifiable risk factor for renal, cardiovascular, and cerebrovascular diseases. Yet, the underlying mechanisms remain poorly understood. The proposed study determines how renal oxygenation and substrate metabolism d...
What is the current status of trial NCT05369416?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 70 participants. The study started on 2021-11-01. Estimated completion is 2030-01-30.
What conditions does trial NCT05369416 study?
This clinical trial studies the following conditions: Hypertension.
What interventions are being tested in trial NCT05369416?
The interventions under investigation include: Low sodium diet (OTHER), high sodium diet (OTHER).
Who is sponsoring clinical trial NCT05369416?
This trial is sponsored by Medical College of Wisconsin, which has 447 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05369416 being conducted?
This trial has 1 study location across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Hypertension
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05369416's enrollment target sits among peer trials
70 334th of 470 higher than 133 of 470 other Hypertension trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hypertension trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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