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NCT04354350 · ClinicalTrials.gov registry record
Replication of the ONTARGET Antihypertensive Trial in Healthcare Claims Data
A clinical trial of Hypertension, sponsored by Brigham and Women's Hospital.
- Completed
- Registry status
- 63,744
- Enrollment target
- 1
- Study location
NCT04354350: Completed study of Hypertension, sponsored by Brigham and Women's Hospital.
NCT04354350 is a study of Hypertension that has completed, run by Brigham and Women's Hospital. The registered enrollment target is 63,744 participants, above the 3,372-participant average among 470 other Hypertension trials with a reported enrollment target (1790% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04354350, a study of Hypertension, has completed, sponsored by Brigham and Women's Hospital.
- COMPLETED
- Registry status
- 63,744 participants
- Enrollment target
- 1
- Study location
Study Summary
Investigators are building an empirical evidence base for real world data through large-scale replication of randomized controlled trials. The investigators' goal is to understand for what types of clinical questions real world data analyses can be conducted with confidence and how to implement such studies.
Primary Outcome
Relative hazard of composite outcome of Heart Failure, Stroke, MI, and Mortality - Please refer to uploaded protocol for full definition due to size limitations.
Conditions Studied
Interventions
- DRUG Ramipril
- DRUG Telmisartan
Study Locations (1)
Massachusetts
- Brigham And Women's Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 63,744 participants |
| Start Date | 2017-09-22 |
| Est. Completion | 2021-02-08 |
What the finished NCT04354350 record still lists
NCT04354350 is an observational study that tracks outcomes without assigning an intervention. Its 63,744 participants enrollment target places it among the larger protocols in the corpus, above the 3,372-participant average among 470 other Hypertension trials with a reported enrollment target (1790% higher).
The record links to 1 condition, with Hypertension appearing as the primary indexed condition, and to 2 interventions - of which Ramipril is the first listed.
NCT04354350 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT04354350 about?
NCT04354350 is a clinical study titled "Replication of the ONTARGET Antihypertensive Trial in Healthcare Claims Data". Investigators are building an empirical evidence base for real world data through large-scale replication of randomized controlled trials. The investigators' goal is to understand for what types of clinical questions real world data analyses can be conducted with confidence and how to implement such...
What is the current status of trial NCT04354350?
This trial is currently completed. The enrollment target is 63,744 participants. The study started on 2017-09-22. Estimated completion is 2021-02-08.
What conditions does trial NCT04354350 study?
This clinical trial studies the following conditions: Hypertension.
What interventions are being tested in trial NCT04354350?
The interventions under investigation include: Ramipril (DRUG), Telmisartan (DRUG).
Who is sponsoring clinical trial NCT04354350?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04354350 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Hypertension
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04354350's enrollment target sits among peer trials
63,744 5th of 470 higher than 466 of 470 other Hypertension trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hypertension trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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