Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03348280 · ClinicalTrials.gov registry record
Vitamin D and Immune Mechanisms of Hypertension in Type 2 Diabetics
A clinical trial of Hypertension and Diabetes Mellitus, Type 2, sponsored by Washington University School of Medicine.
- Active
- Registry status
- 40
- Enrollment target
- 2
- Study locations
NCT03348280: Active study of Hypertension and Diabetes Mellitus, Type 2, sponsored by Washington University School of Medicine.
NCT03348280 is a study of Hypertension and Diabetes Mellitus, Type 2 that is active but no longer recruiting, run by Washington University School of Medicine. The registered enrollment target is 40 participants, below the 3,507-participant average among 470 other Hypertension trials with a reported enrollment target (99% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03348280, a study of Hypertension and Diabetes Mellitus, Type 2, is active but no longer recruiting, sponsored by Washington University School of Medicine.
- ACTIVE NOT RECRUITING
- Registry status
- 40 participants
- Enrollment target
- 2
- Study locations
Study Summary
This trial will evaluate whether a particular type of circulating white blood cell, monocytes, from type 2 diabetics with high blood pressure and vitamin D deficiency vs. sufficiency will induce hormones that increase blood pressure.
Primary Outcome
Blood will be collected for isolation of monocytes. These cells will then be cultured to determine whether there is monocyte stimulation of a hormone that induces high blood pressure (renin) in kidney cells.
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Blood draw
Study Locations (2)
Missouri
- Barnes-Jewish & Washington University Diabetes Center - St Louis
- Washington University - St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2017-09-01 |
| Est. Completion | 2026-12-31 |
What the registry record for NCT03348280 still lists
NCT03348280 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 3,507-participant average among 470 other Hypertension trials with a reported enrollment target (99% lower).
The record links to 3 conditions, with Hypertension appearing as the primary indexed condition, and to 1 intervention - of which Blood draw is the first listed.
NCT03348280 reports a single indexed study location in Missouri.
Frequently Asked Questions
What is clinical trial NCT03348280 about?
NCT03348280 is a clinical study titled "Vitamin D and Immune Mechanisms of Hypertension in Type 2 Diabetics". This trial will evaluate whether a particular type of circulating white blood cell, monocytes, from type 2 diabetics with high blood pressure and vitamin D deficiency vs. sufficiency will induce hormones that increase blood pressure.
What is the current status of trial NCT03348280?
This trial is currently active not recruiting. The enrollment target is 40 participants. The study started on 2017-09-01. Estimated completion is 2026-12-31.
What conditions does trial NCT03348280 study?
This clinical trial studies the following conditions: Hypertension, Diabetes Mellitus, Type 2, Vitamin D Deficiency.
What interventions are being tested in trial NCT03348280?
The interventions under investigation include: Blood draw (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT03348280?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03348280 being conducted?
This trial has 2 study locations across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Hypertension
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03348280's enrollment target sits among peer trials
40 384th of 470 higher than 80 of 470 other Hypertension trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hypertension trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Ketone Ester And Salt (KEAS) in Older Adults
RECRUITING · NA
-
How a Mediterranean Diet With Potatoes Impacts Heart and Metabolic Health in Adults With Pre-Diabetes
RECRUITING · NA
-
Autonomic Regulation of Blood Pressure in Premature and Early Menopausal Women
RECRUITING
-
Conical Forearm and Cylindrical Upper Arm Non-Invasive Blood Pressure (NIBP) Measurements in Pregnant Patients
RECRUITING · NA
-
Comparing Healthcare Visit Recording and Open Notes to Improve Chronic iLlness Care Experience in Older Adults
RECRUITING · NA
-
Childhood-Onset Essential Hypertension Natural History Study
RECRUITING
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01306019 · 40 participants · Phase 1
Lentiviral Gene Transfer for Treatment of Children Older Than Two Years of Age With X-Linked Severe Combined Immunodeficiency (XSCID)
- NCT01608152 · 40 participants
Development of a Video Game for the Improvement of Outcomes in Stem Cell Transplant Survivors
- NCT01668082 · 40 participants · NA
An Investigation of Brain Tumor Metabolism in Patients Undergoing Surgical Resection
- NCT02015013 · 40 participants · Phase 2
Hematopoietic Stem Cell Mobilization in Idiopathic CD4 Lymphocytopenia Patients and Healthy Controls for the Study of T Cell Maturation and Trafficking in Murine Models
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI