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NCT02425566 · ClinicalTrials.gov registry record · Phase 1

Role of Sympathetic Activity and Splanchnic Capacitance in Hypertension

A Phase 1 study of Hypertension, sponsored by Vanderbilt University.

Active
Registry status
Phase 1
Development phase
12
Enrollment target
1
Study location

NCT02425566 is a Phase 1 study of Hypertension that is active but no longer recruiting, run by Vanderbilt University. The registered enrollment target is 12 participants, below the 3,507-participant average among 470 other Hypertension trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT02425566, a Phase 1 study of Hypertension, is active but no longer recruiting, sponsored by Vanderbilt University.

ACTIVE NOT RECRUITING
Registry status
Phase 1
Development phase
12 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to better understand the role of the abdominal veins (splanchnic capacitance) and the sympathetic nervous system in human hypertension. The investigators will test the hypothesis that constriction of abdominal veins due to sympathetic activation contributes to human hypertension. Splanchnic capacitance will be assessed in normotensive and hypertensive subjects at baseline and during acute blockade of the autonomic nervous system.

Conditions Studied

Hypertension

Interventions

  • DRUG Trimethaphan
  • DRUG Nitroglycerin

Study Locations (1)

Tennessee

  • Autonomic Dysfunction Center - Nashville

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2015-04
Est. Completion 2026-08
Phase Phase 1

Sponsor

Vanderbilt University

430 total trials

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What the Registry Record Tells You About NCT02425566

The ClinicalTrials.gov registry entry for NCT02425566 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 3,507-participant average among 470 other Hypertension trials with a reported enrollment target (100% lower). The listed sponsor is Vanderbilt University, which has 430 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Hypertension appearing as the primary indexed condition, and to 2 interventions - of which Trimethaphan is the first listed.

NCT02425566 reports 1 study location spanning 1 distinct geographic area - top geographies include Tennessee.

Frequently Asked Questions

What is clinical trial NCT02425566 about?

NCT02425566 is a clinical study titled "Role of Sympathetic Activity and Splanchnic Capacitance in Hypertension". The purpose of this study is to better understand the role of the abdominal veins (splanchnic capacitance) and the sympathetic nervous system in human hypertension. The investigators will test the hypothesis that constriction of abdominal veins due to sympathetic activation contributes to human hype...

What is the current status of trial NCT02425566?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 12 participants. The study started on 2015-04. Estimated completion is 2026-08.

What conditions does trial NCT02425566 study?

This clinical trial studies the following conditions: Hypertension.

What interventions are being tested in trial NCT02425566?

The interventions under investigation include: Trimethaphan (DRUG), Nitroglycerin (DRUG).

Who is sponsoring clinical trial NCT02425566?

This trial is sponsored by Vanderbilt University, which has 430 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02425566 being conducted?

This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.