Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT04384263 · ClinicalTrials.gov registry record · NA

The Influence of Tai Chi Practice on Blood Pressure and Brain Health Among Older Adults with Hypertension (ACTION)

A NA study of Hypertension and Cognitive Decline, sponsored by University of Connecticut.

Active
Registry status
NA
Development phase
20
Enrollment target
1
Study location

NCT04384263: Active NA study of Hypertension and Cognitive Decline, sponsored by University of Connecticut.

NCT04384263 is a NA study of Hypertension and Cognitive Decline that is active but no longer recruiting, run by University of Connecticut. The registered enrollment target is 20 participants, below the 3,507-participant average among 470 other Hypertension trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT04384263, a NA study of Hypertension and Cognitive Decline, is active but no longer recruiting, sponsored by University of Connecticut.

ACTIVE NOT RECRUITING
Registry status
NA
Development phase
20 participants
Enrollment target
1
Study location

Study Summary

High blood pressure and poor cognitive function are two common health problems among older adults in the United States. They are also closely related because high blood pressure may lead to negative changes in brain structure and function such as poor brain blood flow that can cause poor cognitive function. Executive function is one type of cognitive function that let people plan and perform difficult tasks. It is commonly damaged by high blood pressure. It is also very important for older adults because they need good executive function to live on their own. Tai Chi is a good exercise option for older adults because it is safe, fun, and social. Research studies show that Tai Chi can reduce blood pressure and improve cognitive function, especially executive function. However, researchers do know if these heart and brain health benefits of Tai Chi are connected. In the ACTION study, researchers will first measure how a single session of Tai Chi followed by a 12-week online Tai Chi program with easy movements changes blood pressure and cognitive function, focusing on executive function. Then, researchers will test if these changes in heart and brain health are connected, and if they are connected through the changes in brain structure and function. Both the single session and 12-week online Tai Chi program will be practiced by a group of older adults with high blood pressure and normal cognitive function. They will be new to Tai Chi and not exercising regularly. The hypotheses of the ACTION study are that practicing Tai Chi is good for the heart and brain of older adults with high blood pressure. Specifically, relaxing Tai Chi with gentle movements will reduce blood pressure, and thereby improve cognitive function, particularly executive function.

Primary Outcome

Investigators will measure resting systolic BP (RSBP) and resting diastolic BP (RDBP) according to standards set by the American Heart Association using the OMRON automated BP monitors model HEM-705CPN in mmHg.

Interventions

  • BEHAVIORAL Tai Chi

Study Locations (1)

Connecticut

  • University of Connecticut - Storrs

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2021-06-01
Est. Completion 2025-12-31
Phase NA
University of Connecticut

107 total trials

What the registry record for NCT04384263 still lists

NCT04384263 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 3,507-participant average among 470 other Hypertension trials with a reported enrollment target (99% lower).

The record links to 2 conditions, with Hypertension appearing as the primary indexed condition, and to 1 intervention - of which Tai Chi is the first listed.

NCT04384263 reports a single indexed study location in Connecticut.

Frequently Asked Questions

What is clinical trial NCT04384263 about?

NCT04384263 is a clinical study titled "The Influence of Tai Chi Practice on Blood Pressure and Brain Health Among Older Adults with Hypertension (ACTION)". High blood pressure and poor cognitive function are two common health problems among older adults in the United States. They are also closely related because high blood pressure may lead to negative changes in brain structure and function such as poor brain blood flow that can cause poor cognitive f...

What is the current status of trial NCT04384263?

This trial is currently active not recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2021-06-01. Estimated completion is 2025-12-31.

What conditions does trial NCT04384263 study?

This clinical trial studies the following conditions: Hypertension, Cognitive Decline.

What interventions are being tested in trial NCT04384263?

The interventions under investigation include: Tai Chi (BEHAVIORAL).

Who is sponsoring clinical trial NCT04384263?

This trial is sponsored by University of Connecticut, which has 107 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04384263 being conducted?

This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Hypertension

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04384263's enrollment target sits among peer trials

20 438th of 470 higher than 24 of 470 other Hypertension trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Hypertension trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT00573339 · 20 participants

    Cardiac Magnetic Resonance Imaging (MRI) Normal Reference Control Group Testing

  • NCT00692939 · 20 participants · Phase 1

    Autologous Stem Cell Transplantation for Crohn's Disease

  • NCT00967785 · 20 participants · Phase 1

    A Phase I Study of Mozobil in the Treatment of Patients With WHIMS

  • NCT01406691 · 20 participants · Phase 4

    Light Flashes to Treat Delayed Sleep Phase Disorder (DSPD)

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT04384263, the US trial registry maintained by the National Library of Medicine. NCT04384263 (small enrollment · single site footprint · active not recruiting) retrieved and formatted by PlainTrial, see methodology.