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ACTIVE NOT RECRUITING Phase 1

Study of NGM707 As Monotherapy and in Combination with Pembrolizumab in Advanced or Metastatic Solid Tumor Malignancies

NCT04913337 · View on ClinicalTrials.gov ↗

Study Summary

Study of NGM707 as Monotherapy and in Combination with Pembrolizumab in Advanced or Metastatic Solid Tumor Malignancies

Interventions

  • DRUG NGM707
  • DRUG NGM707 plus pembrolizumab (KEYTRUDA®)

Study Locations (20)

Texas

  • NGM Clinical Study Site — Dallas
  • NGM Clinical Study Site — Dallas
  • NGM Clinical Study Site — Houston
  • NGM Clinical Study Site — San Antonio
  • NGM Clinical Study Site — San Antonio

California

  • NGM Clinical Study Site — Los Angeles
  • NGM Clinical Study Site — Newport Beach
  • NGM Clinical Study Site — Santa Monica
  • NGM Clinical Study Site — Santa Rosa

Colorado

  • NGM Clinical Study Site — Lone Tree

District of Columbia

  • NGM Clinical Study Site — Washington D.C.

Florida

  • NGM Clinical Study Site — Sarasota

Maryland

  • NGM Clinical Study Site — Baltimore

Massachusetts

  • NGM Clinical Study Site — Boston

Michigan

  • NGM Clinical Study Site — Grand Rapids

Trial Details

FieldValue
Enrollment Target 179 participants
Start Date 2021-06-09
Est. Completion 2025-07
Phase Phase 1

Sponsor

NGM Biopharmaceuticals

10 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT04913337

The ClinicalTrials.gov registry entry for NCT04913337 describes a study currently listed as active not recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 179 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is NGM Biopharmaceuticals, which has 10 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 10 conditions, with Breast Cancer appearing as the primary indexed condition, and to 2 interventions — of which NGM707 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT04913337 reports 20 study locations spanning 13 distinct geographic areas — top geographies include Texas, California, Colorado. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT04913337 about?

NCT04913337 is a clinical study titled "Study of NGM707 As Monotherapy and in Combination with Pembrolizumab in Advanced or Metastatic Solid Tumor Malignancies". Study of NGM707 as Monotherapy and in Combination with Pembrolizumab in Advanced or Metastatic Solid Tumor Malignancies

What is the current status of trial NCT04913337?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 179 participants. The study started on 2021-06-09. Estimated completion is 2025-07.

What conditions does trial NCT04913337 study?

This clinical trial studies the following conditions: Breast Cancer, Melanoma, Glioblastoma, Gastric Cancer, Non Small Cell Lung Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT04913337?

The interventions under investigation include: NGM707 (DRUG), NGM707 plus pembrolizumab (KEYTRUDA®) (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT04913337?

This trial is sponsored by NGM Biopharmaceuticals, which has 10 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT04913337 being conducted?

This trial has 20 study locations across California, Colorado, District of Columbia, Florida, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial