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NCT06298916 · ClinicalTrials.gov registry record · Phase 1
64Cu-LNTH-1363S in Patients With Sarcoma or Gastrointestinal Tract Cancer
A Phase 1 study of Colorectal Cancer and Pancreatic Cancer, sponsored by Lantheus Medical Imaging.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 26
- Enrollment target
- 5
- Study locations
NCT06298916: Recruiting Phase 1 study of Colorectal Cancer and Pancreatic Cancer, sponsored by Lantheus Medical Imaging.
NCT06298916 is a Phase 1 study of Colorectal Cancer and Pancreatic Cancer that is actively recruiting participants, run by Lantheus Medical Imaging. The registered enrollment target is 26 participants, below the 1,545-participant average among 381 other Colorectal Cancer trials with a reported enrollment target (98% lower). The trial reports 5 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06298916, a Phase 1 study of Colorectal Cancer and Pancreatic Cancer, is actively recruiting participants, sponsored by Lantheus Medical Imaging.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 26 participants
- Enrollment target
- 5
- Study locations
Study Summary
This is a multicenter, open-label, prospective Phase 1/2a study to assess safety and tolerability, establish dosimetry and to identify an optimal imaging dose (radioactivity) and imaging time window of 64Cu-LNTH-1363S, and to compare its imaging biodistribution with FAP expression by IHC in patients with sarcomas or GIT cancers. The study will be conducted in 2 parts (Part 1 and Part 2).
Primary Outcome
Time Activity Curves (TACs) describing percentage of the injected activity versus time will be derived for selected organs and tumor lesions and absorbed radiation doses of 64Cu-LNTH-1363S in critical organs (e.g., kidneys, liver) will be estimated.
Conditions Studied
Interventions
- COMBINATION_PRODUCT 64Cu-LNTH-1363S
Study Locations (5)
California
- City of Hope - Duarte
- UC Irvine Health - Chao Family Comprehensive Cancer Center - Orange
- Stanford Hospital & Clinics - Stanford
Michigan
- BAMF Health, Inc. - Grand Rapids
Ohio
- Cincinnati Children's Hospital Medical Center - Cincinnati
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 26 participants |
| Start Date | 2025-08 |
| Est. Completion | 2026-04 |
| Phase | Phase 1 |
What NCT06298916 shows while recruiting
NCT06298916 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 26 participants, a relatively small participant target, below the 1,545-participant average among 381 other Colorectal Cancer trials with a reported enrollment target (98% lower).
The record links to 6 conditions, with Colorectal Cancer appearing as the primary indexed condition, and to 1 intervention - of which 64Cu-LNTH-1363S is the first listed.
NCT06298916 lists 5 locations in 3 states (California, Michigan, Ohio).
Frequently Asked Questions
What is clinical trial NCT06298916 about?
NCT06298916 is a clinical study titled "64Cu-LNTH-1363S in Patients With Sarcoma or Gastrointestinal Tract Cancer". This is a multicenter, open-label, prospective Phase 1/2a study to assess safety and tolerability, establish dosimetry and to identify an optimal imaging dose (radioactivity) and imaging time window of 64Cu-LNTH-1363S, and to compare its imaging biodistribution with FAP expression by IHC in patients...
What is the current status of trial NCT06298916?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 26 participants. The study started on 2025-08. Estimated completion is 2026-04.
What conditions does trial NCT06298916 study?
This clinical trial studies the following conditions: Colorectal Cancer, Pancreatic Cancer, Gastric Cancer, Esophageal Cancer, Sarcoma.
What interventions are being tested in trial NCT06298916?
The interventions under investigation include: 64Cu-LNTH-1363S (COMBINATION_PRODUCT).
Who is sponsoring clinical trial NCT06298916?
This trial is sponsored by Lantheus Medical Imaging, which has 22 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06298916 being conducted?
This trial has 5 study locations across California, Michigan, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Colorectal Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06298916's enrollment target sits among peer trials
26 329th of 381 higher than 53 of 381 other Colorectal Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Colorectal Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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