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ACTIVE NOT RECRUITING Phase 1

First in Human Study of TORL-2-307-ADC in Participants With Advanced Cancer

NCT05156866 · View on ClinicalTrials.gov ↗

Study Summary

This first-in-human study will evaluate the safety, tolerability, pharmacokinetics, and antitumor activity of TORL-2-307-ADC in patients with advanced cancer

Interventions

  • DRUG TORL-2-307-ADC

Study Locations (12)

Texas

  • Texas Oncology-Austin — Austin
  • Texas Oncology-Dallas — Dallas
  • START San Antonio — San Antonio
  • Texas Oncology-Tyler — Tyler

California

  • Providence St. Jude Medical Center — Fullerton
  • UCLA - JCCC Clinical Research Unit — Los Angeles
  • Torrance Memorial Medical — Torrance

Other

  • Seoul National University Hospital — Seoul
  • Severance Hospital, Yonsei University Health System — Seoul
  • Seoul National University Bundang Hospital — Seoul

Indiana

  • Fort Wayne Medical Oncology and Hematology — Fort Wayne

Missouri

  • Washington University School of Medicine-Siteman Cancer Center — St Louis

Trial Details

FieldValue
Enrollment Target 163 participants
Start Date 2022-02-02
Est. Completion 2027-02-15
Phase Phase 1

Sponsor

TORL Biotherapeutics

7 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05156866

The ClinicalTrials.gov registry entry for NCT05156866 describes a study currently listed as active not recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 163 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is TORL Biotherapeutics, which has 7 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 4 conditions, with Advanced Solid Tumor appearing as the primary indexed condition, and to 1 intervention — of which TORL-2-307-ADC is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05156866 reports 12 study locations spanning 5 distinct geographic areas — top geographies include Texas, California, Other. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05156866 about?

NCT05156866 is a clinical study titled "First in Human Study of TORL-2-307-ADC in Participants With Advanced Cancer". This first-in-human study will evaluate the safety, tolerability, pharmacokinetics, and antitumor activity of TORL-2-307-ADC in patients with advanced cancer

What is the current status of trial NCT05156866?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 163 participants. The study started on 2022-02-02. Estimated completion is 2027-02-15.

What conditions does trial NCT05156866 study?

This clinical trial studies the following conditions: Advanced Solid Tumor, Gastric Cancer, Pancreas Cancer, Gastroesophageal Junction Adenocarcinoma. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05156866?

The interventions under investigation include: TORL-2-307-ADC (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05156866?

This trial is sponsored by TORL Biotherapeutics, which has 7 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05156866 being conducted?

This trial has 12 study locations across California, Indiana, Missouri, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial