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ClinicalTrials.gov 79 recruiting now official registry

Dementia clinical trials

79 of 202 indexed Dementia trials are currently recruiting.

202 US clinical trials · 79 currently recruiting

Dementia is the subject of 202 registered US clinical trials on ClinicalTrials.gov, 79 of them currently open to new participants. 13 are in Phase 3-4 (later-stage) and 29 in Phase 1-2 (earlier-stage). The most active sponsor is University of Washington, running 8 of these trials.

The research picture

Dementia has 202 registered US clinical trials, 79 of them open to new participants right now, about 39% of the total.

79
recruiting participants now
39%
of trials open to enrollment
13
in Phase 3–4 (later-stage)
8
top sponsor: University of Washington
Phase 110Phase 219Phase 310Phase 43

Active & Recent Trials

202 total, page 2 of 5

RECRUITING NA 100 participants

A Multi-Modal Combination Intervention to Promote Cognitive Function in Older Intensive Care Unit Survivors

University of Washington

NCT06411561

RECRUITING NA 90 participants

Apolipoprotein E (APOE) Genotype Effects on Triglycerides and Blood Flow in the Human Brain

University of Washington

NCT04692441

RECRUITING NA 80 participants

Sleep Enhancement for Older Adults Living With Memory Loss And Their Care Partners

Emory University

NCT06250725

RECRUITING NA 80 participants

Testing & Refinement of CarePair: An Assessment and Referral Platform to Support Family Caregivers of Alzheimer's Disease and Related Dementias.

University of Southern California

NCT06418971

RECRUITING NA 70 participants

Early-Stage Partner in Care Living Alone Plus

Arizona State University

NCT06962111

RECRUITING NA 68 participants

Caregivers Preparing for Their Own Health Care Emergency

University of California, Davis

NCT06635876

RECRUITING Phase 1 66 participants

Ferritin and Iron Burden in SAH sIRB

Duke University

NCT03754725

RECRUITING NA 65 participants

Comparing Structured Retrieval Practice and Reading-Based Education for Dementia Caregivers

Virginia Wesleyan University

NCT07413406

RECRUITING NA 62 participants

Enhancing Shared Decision-making to Guide Care for People With Dementia and Diabetes

Indiana University

NCT05643144

RECRUITING Phase 2 60 participants

Clinical Trial Evaluating the Efficacy of AGB101 for Reducing Hippocampal Overactivity in Older Adults

Johns Hopkins University

NCT06919926

RECRUITING Phase 1 60 participants

Exploration of an Online Education Program to Support Caregivers' Knowledge Transfer

Texas Christian University

NCT07377331

RECRUITING NA 60 participants

Development of a Personalized, Psychosocial Intervention for Menopausal Individuals With Elevated Dementia Risk

University of Chicago

NCT06965686

RECRUITING 60 participants

Delirium Identification in Older Patients With Alzheimer's and Other Related Dementias In the Emergency Department

Ohio State University

NCT06326424

RECRUITING NA 60 participants

E-Tailored Pain Management Support for Dementia Family Caregivers: Feasibility of the PACE-app

University of Iowa

NCT07032350

RECRUITING NA 60 participants

University of Central Florida Music Study

University of Central Florida

NCT07306065

RECRUITING NA 60 participants

Web-based Cognitive Behavioral Treatment for Insomnia in Dementia Caregivers

University of South Florida

NCT04632628

RECRUITING NA 60 participants

Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia

University of Texas at Austin

NCT05741853

RECRUITING 50 participants

Dynamic Light Scattering Ocular Measurement in the Detection of Dementia

MD Stem Cells

NCT06613971

RECRUITING NA 50 participants

Resilient Together for Dementia (RT-D)

Icahn School of Medicine at Mount Sinai

NCT06619327

RECRUITING NA 48 participants

Caregiver Bootcamp

Emory University

NCT07006116

RECRUITING NA 40 participants

DECIDE: Dyads and Families

Emory University

NCT05139290

RECRUITING NA 40 participants

Community Health Worker-Led Transition Support for Persons Living With Dementia and Caregivers

University of Texas at Austin

NCT06831318

RECRUITING 40 participants

Passive Sensor Identification of Digital Biomarkers to Assess Effects of Orally Administered Nicotinamide Riboside

Mclean Hospital

NCT05245903

RECRUITING NA 32 participants

Environmental and Sensory Intervention for Nursing Home Residents With Dementia Who Exhibit Persistent Vocalizations

Drexel University

NCT06568107

RECRUITING NA 30 participants

Combating Alzheimer's Through Sleep and Exercise

University of Miami

NCT04855630

RECRUITING 30 participants

Investigating Dynamic Interactions in Distributed Cognitive Control Networks

University of Alabama at Birmingham

NCT05927974

RECRUITING 25 participants

Assessing Cognitive Decline at Home

Stanford University

NCT06704971

RECRUITING 20 participants

OCT Angiography and NRAI in Dementia

Oregon Health and Science University

NCT03761381

RECRUITING Phase 2 16 participants

Assessment of Foralumab Safety and Modulation of Microglial Activation in Alzheimer's Disease

Brigham and Women's Hospital

NCT06489548

ACTIVE NOT RECRUITING NA 41,500 participants

ToolBox Detect: Low Cost Detection of Cognitive Decline in Primary Care Settings

Northwestern University

NCT04852601

ACTIVE NOT RECRUITING 19,114 participants

Aspirin in Reducing Events in the Elderly-Extension (ASPREE-XT)

Anne Murray

NCT07224347

ACTIVE NOT RECRUITING 13,435 participants

Sex-specific Risk Factors and Trajectories of Blood Biomarkers for Alzheimer's Disease and Related Dementias

Anne Murray

NCT07224139

ACTIVE NOT RECRUITING NA 5,043 participants

Changing Talk Online Training (CHATO) National Trial

University of Kansas Medical Center

NCT04610944

ACTIVE NOT RECRUITING NA 3,417 participants

The Brain Health Study: A Pragmatic, Patient-Centered Trial

Kaiser Permanente

NCT05356702

ACTIVE NOT RECRUITING 2,000 participants

Screening for Memory Studies

John Wesson Ashford Jr

NCT01123018

ACTIVE NOT RECRUITING 1,892 participants

Biomarkers for Vascular Contributions to Cognitive Impairment and Dementia Consortium

Massachusetts General Hospital

NCT06284213

ACTIVE NOT RECRUITING Phase 3 1,175 participants

A Study of Different Donanemab (LY3002813) Dosing Regimens in Adults With Early Alzheimer's Disease (TRAILBLAZER-ALZ 6)

Eli Lilly and Company

NCT05738486

ACTIVE NOT RECRUITING 826 participants

The BRAIN Intensive Care Unit (ICU) Study: Bringing to Light the Risk Factors

Vanderbilt University Medical Center

NCT00392795

ACTIVE NOT RECRUITING NA 760 participants

Minnesota Inclusive LTSS for LGBTQ Seniors

University of Minnesota

NCT05530590

ACTIVE NOT RECRUITING 634 participants

Brain Attack Surveillance in Corpus Christi--Cognitive (BASIC-Cognitive)

University of Michigan

NCT03403257

ACTIVE NOT RECRUITING Phase 3 629 participants

ACHIEVE Brain Health Follow-Up Study

Johns Hopkins University

NCT05532657

ACTIVE NOT RECRUITING 600 participants

BRINK (BRain In Kidney Disease) Memory Study 2.0

Anne Murray

NCT04975464

ACTIVE NOT RECRUITING Phase 2 523 participants

A Study of JNJ-63733657 in Participants With Early Alzheimer's Disease

Janssen Research & Development

NCT04619420

ACTIVE NOT RECRUITING Phase 2 490 participants

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation. Master Protocol DIAN-TU-001

Washington University School of Medicine

NCT01760005

ACTIVE NOT RECRUITING 400 participants

Quality Improvement and Clinical Utility PrecivityAD2(TM) Clinician Survey

C2N Diagnostics

NCT06025877

ACTIVE NOT RECRUITING NA 355 participants

A Study of Caregiver Connections Via Technology in Dementia

Mayo Clinic

NCT05779839

ACTIVE NOT RECRUITING Phase 2 350 participants

A Study to Evaluate the Efficacy and Safety of MK-1167 in Participants With Alzheimer's Disease Dementia (MK-1167-008)

Merck Sharp & Dohme

NCT06721156

ACTIVE NOT RECRUITING NA 344 participants

Reducing Risk of Dementia Through Deprescribing

Indiana University

NCT04270474

ACTIVE NOT RECRUITING NA 342 participants

The PorchLight Project

University of Minnesota

NCT05550727

ACTIVE NOT RECRUITING NA 288 participants

PLAN: Dementia Literacy Education and Navigation for Korean Elders With Probable Dementia and Their Caregivers

Johns Hopkins University

NCT03909347

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Phase Distribution

PhaseTrial count
Phase 1 10
Phase 2 19
Phase 3 10
Phase 4 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Dementia Trial Landscape

202 indexed Dementia studies · 79 recruiting (39%).

Phase mix: 13 late (III/IV) vs 29 early (I/II).

Top sponsor: University of Washington (8 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Dementia?

PlainTrial tracks 202 US clinical trials for Dementia, of which 79 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Dementia?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.