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Dementia clinical trials
79 of 202 indexed Dementia trials are currently recruiting.
202 US clinical trials · 79 currently recruiting
Dementia is the subject of 202 registered US clinical trials on ClinicalTrials.gov, 79 of them currently open to new participants. 13 are in Phase 3-4 (later-stage) and 29 in Phase 1-2 (earlier-stage). The most active sponsor is University of Washington, running 8 of these trials.
The research picture
Dementia has 202 registered US clinical trials, 79 of them open to new participants right now, about 39% of the total.
- 79
- recruiting participants now
- 39%
- of trials open to enrollment
- 13
- in Phase 3–4 (later-stage)
- 8
- top sponsor: University of Washington
Active & Recent Trials
202 total, page 2 of 5
A Multi-Modal Combination Intervention to Promote Cognitive Function in Older Intensive Care Unit Survivors
University of Washington
NCT06411561
Apolipoprotein E (APOE) Genotype Effects on Triglycerides and Blood Flow in the Human Brain
University of Washington
NCT04692441
Sleep Enhancement for Older Adults Living With Memory Loss And Their Care Partners
Emory University
NCT06250725
Testing & Refinement of CarePair: An Assessment and Referral Platform to Support Family Caregivers of Alzheimer's Disease and Related Dementias.
University of Southern California
NCT06418971
Early-Stage Partner in Care Living Alone Plus
Arizona State University
NCT06962111
Caregivers Preparing for Their Own Health Care Emergency
University of California, Davis
NCT06635876
Ferritin and Iron Burden in SAH sIRB
Duke University
NCT03754725
Comparing Structured Retrieval Practice and Reading-Based Education for Dementia Caregivers
Virginia Wesleyan University
NCT07413406
Enhancing Shared Decision-making to Guide Care for People With Dementia and Diabetes
Indiana University
NCT05643144
Clinical Trial Evaluating the Efficacy of AGB101 for Reducing Hippocampal Overactivity in Older Adults
Johns Hopkins University
NCT06919926
Exploration of an Online Education Program to Support Caregivers' Knowledge Transfer
Texas Christian University
NCT07377331
Development of a Personalized, Psychosocial Intervention for Menopausal Individuals With Elevated Dementia Risk
University of Chicago
NCT06965686
Delirium Identification in Older Patients With Alzheimer's and Other Related Dementias In the Emergency Department
Ohio State University
NCT06326424
E-Tailored Pain Management Support for Dementia Family Caregivers: Feasibility of the PACE-app
University of Iowa
NCT07032350
University of Central Florida Music Study
University of Central Florida
NCT07306065
Web-based Cognitive Behavioral Treatment for Insomnia in Dementia Caregivers
University of South Florida
NCT04632628
Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia
University of Texas at Austin
NCT05741853
Dynamic Light Scattering Ocular Measurement in the Detection of Dementia
MD Stem Cells
NCT06613971
Resilient Together for Dementia (RT-D)
Icahn School of Medicine at Mount Sinai
NCT06619327
Caregiver Bootcamp
Emory University
NCT07006116
DECIDE: Dyads and Families
Emory University
NCT05139290
Community Health Worker-Led Transition Support for Persons Living With Dementia and Caregivers
University of Texas at Austin
NCT06831318
Passive Sensor Identification of Digital Biomarkers to Assess Effects of Orally Administered Nicotinamide Riboside
Mclean Hospital
NCT05245903
Environmental and Sensory Intervention for Nursing Home Residents With Dementia Who Exhibit Persistent Vocalizations
Drexel University
NCT06568107
Combating Alzheimer's Through Sleep and Exercise
University of Miami
NCT04855630
Investigating Dynamic Interactions in Distributed Cognitive Control Networks
University of Alabama at Birmingham
NCT05927974
Assessing Cognitive Decline at Home
Stanford University
NCT06704971
OCT Angiography and NRAI in Dementia
Oregon Health and Science University
NCT03761381
Assessment of Foralumab Safety and Modulation of Microglial Activation in Alzheimer's Disease
Brigham and Women's Hospital
NCT06489548
ToolBox Detect: Low Cost Detection of Cognitive Decline in Primary Care Settings
Northwestern University
NCT04852601
Aspirin in Reducing Events in the Elderly-Extension (ASPREE-XT)
Anne Murray
NCT07224347
Sex-specific Risk Factors and Trajectories of Blood Biomarkers for Alzheimer's Disease and Related Dementias
Anne Murray
NCT07224139
Changing Talk Online Training (CHATO) National Trial
University of Kansas Medical Center
NCT04610944
The Brain Health Study: A Pragmatic, Patient-Centered Trial
Kaiser Permanente
NCT05356702
Screening for Memory Studies
John Wesson Ashford Jr
NCT01123018
Biomarkers for Vascular Contributions to Cognitive Impairment and Dementia Consortium
Massachusetts General Hospital
NCT06284213
A Study of Different Donanemab (LY3002813) Dosing Regimens in Adults With Early Alzheimer's Disease (TRAILBLAZER-ALZ 6)
Eli Lilly and Company
NCT05738486
The BRAIN Intensive Care Unit (ICU) Study: Bringing to Light the Risk Factors
Vanderbilt University Medical Center
NCT00392795
Minnesota Inclusive LTSS for LGBTQ Seniors
University of Minnesota
NCT05530590
Brain Attack Surveillance in Corpus Christi--Cognitive (BASIC-Cognitive)
University of Michigan
NCT03403257
ACHIEVE Brain Health Follow-Up Study
Johns Hopkins University
NCT05532657
BRINK (BRain In Kidney Disease) Memory Study 2.0
Anne Murray
NCT04975464
A Study of JNJ-63733657 in Participants With Early Alzheimer's Disease
Janssen Research & Development
NCT04619420
Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation. Master Protocol DIAN-TU-001
Washington University School of Medicine
NCT01760005
Quality Improvement and Clinical Utility PrecivityAD2(TM) Clinician Survey
C2N Diagnostics
NCT06025877
A Study of Caregiver Connections Via Technology in Dementia
Mayo Clinic
NCT05779839
A Study to Evaluate the Efficacy and Safety of MK-1167 in Participants With Alzheimer's Disease Dementia (MK-1167-008)
Merck Sharp & Dohme
NCT06721156
Reducing Risk of Dementia Through Deprescribing
Indiana University
NCT04270474
The PorchLight Project
University of Minnesota
NCT05550727
PLAN: Dementia Literacy Education and Navigation for Korean Elders With Probable Dementia and Their Caregivers
Johns Hopkins University
NCT03909347
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 10 |
| Phase 2 | 19 |
| Phase 3 | 10 |
| Phase 4 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Dementia Trial Landscape
202 indexed Dementia studies · 79 recruiting (39%).
Phase mix: 13 late (III/IV) vs 29 early (I/II).
Top sponsor: University of Washington (8 trials), 9 others listed. 50 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Dementia?
PlainTrial tracks 202 US clinical trials for Dementia, of which 79 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Dementia?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.