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ClinicalTrials.gov 79 recruiting now early-phase tilt #48 of 28,707 conditions

Dementia: early-phase trial registry

79 of 202 indexed Dementia trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #48 of 28,707 conditions by registered trial count.

202 US clinical trials · 79 currently recruiting · #48 of 28,707 conditions by registered trial count

Dementia: 202 US clinical trials tracked, 79 recruiting.

Dementia is the subject of 202 registered US clinical trials on ClinicalTrials.gov, 79 of them currently open to new participants. 13 are in Phase 3-4 (later-stage) and 29 in Phase 1-2 (earlier-stage). The most active sponsor is University of Washington, running 8 of these trials.

Enrollment posture brief

Registry condition dementia

OPEN 79 | RECR 39% | LATE 13 | EARLY 29 | RANK #48 | SPON 8

Nearest open-share peer: Advanced Non-Small-Cell Lung Cancer (39% recruiting · 23 trials)

Spinal Cord Injuries53.2%Glioblastoma39%Dementia (this)39%Atrial Fibrillation29.4%Rheumatoid Arthritis18.6%
Open-enrollment share among volume-matched conditions near Dementia

Dementia lists 79 open slots (39% of 202 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Dementia on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Dementia is recruiting above its size-band peers.

    79 of 202 indexed trials (39.1%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Dementia trials is spread across many organizations.

    University of Washington accounts for 8 of 202 trials (4%). 110 distinct sponsors appear on at least one study for this condition label.

  3. Typical Dementia enrolment sits around 154 participants.

    Median target enrolment is 154 among the 200 trials that report a genuine target (sentinel values excluded). 80 of those (40%) plan for fewer than 100 participants.

  4. Dementia research is mostly interventional.

    157 interventional and 45 observational studies make up this index (77.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 110Phase 219Phase 310Phase 43

Open and recent trials

202 total, page 2 of 5

RECRUITING NA 100 participants

A Multi-Modal Combination Intervention to Promote Cognitive Function in Older Intensive Care Unit Survivors

University of Washington

NCT06411561

RECRUITING NA 90 participants

Apolipoprotein E (APOE) Genotype Effects on Triglycerides and Blood Flow in the Human Brain

University of Washington

NCT04692441

RECRUITING NA 80 participants

Sleep Enhancement for Older Adults Living With Memory Loss And Their Care Partners

Emory University

NCT06250725

RECRUITING NA 80 participants

Testing & Refinement of CarePair: An Assessment and Referral Platform to Support Family Caregivers of Alzheimer's Disease and Related Dementias.

University of Southern California

NCT06418971

RECRUITING NA 70 participants

Early-Stage Partner in Care Living Alone Plus

Arizona State University

NCT06962111

RECRUITING NA 68 participants

Caregivers Preparing for Their Own Health Care Emergency

University of California, Davis

NCT06635876

RECRUITING Phase 1 66 participants

Ferritin and Iron Burden in SAH sIRB

Duke University

NCT03754725

RECRUITING NA 65 participants

Comparing Structured Retrieval Practice and Reading-Based Education for Dementia Caregivers

Virginia Wesleyan University

NCT07413406

RECRUITING NA 62 participants

Enhancing Shared Decision-making to Guide Care for People With Dementia and Diabetes

Indiana University

NCT05643144

RECRUITING Phase 2 60 participants

Clinical Trial Evaluating the Efficacy of AGB101 for Reducing Hippocampal Overactivity in Older Adults

Johns Hopkins University

NCT06919926

RECRUITING Phase 1 60 participants

Exploration of an Online Education Program to Support Caregivers' Knowledge Transfer

Texas Christian University

NCT07377331

RECRUITING NA 60 participants

Development of a Personalized, Psychosocial Intervention for Menopausal Individuals With Elevated Dementia Risk

University of Chicago

NCT06965686

RECRUITING 60 participants

Delirium Identification in Older Patients With Alzheimer's and Other Related Dementias In the Emergency Department

Ohio State University

NCT06326424

RECRUITING NA 60 participants

E-Tailored Pain Management Support for Dementia Family Caregivers: Feasibility of the PACE-app

University of Iowa

NCT07032350

RECRUITING NA 60 participants

University of Central Florida Music Study

University of Central Florida

NCT07306065

RECRUITING NA 60 participants

Web-based Cognitive Behavioral Treatment for Insomnia in Dementia Caregivers

University of South Florida

NCT04632628

RECRUITING NA 60 participants

Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia

University of Texas at Austin

NCT05741853

RECRUITING 50 participants

Dynamic Light Scattering Ocular Measurement in the Detection of Dementia

MD Stem Cells

NCT06613971

RECRUITING NA 50 participants

Resilient Together for Dementia (RT-D)

Icahn School of Medicine at Mount Sinai

NCT06619327

RECRUITING NA 48 participants

Caregiver Bootcamp

Emory University

NCT07006116

RECRUITING NA 40 participants

DECIDE: Dyads and Families

Emory University

NCT05139290

RECRUITING NA 40 participants

Community Health Worker-Led Transition Support for Persons Living With Dementia and Caregivers

University of Texas at Austin

NCT06831318

RECRUITING 40 participants

Passive Sensor Identification of Digital Biomarkers to Assess Effects of Orally Administered Nicotinamide Riboside

Mclean Hospital

NCT05245903

RECRUITING NA 32 participants

Environmental and Sensory Intervention for Nursing Home Residents With Dementia Who Exhibit Persistent Vocalizations

Drexel University

NCT06568107

RECRUITING NA 30 participants

Combating Alzheimer's Through Sleep and Exercise

University of Miami

NCT04855630

RECRUITING 30 participants

Investigating Dynamic Interactions in Distributed Cognitive Control Networks

University of Alabama at Birmingham

NCT05927974

RECRUITING 25 participants

Assessing Cognitive Decline at Home

Stanford University

NCT06704971

RECRUITING 20 participants

OCT Angiography and NRAI in Dementia

Oregon Health and Science University

NCT03761381

RECRUITING Phase 2 16 participants

Assessment of Foralumab Safety and Modulation of Microglial Activation in Alzheimer's Disease

Brigham and Women's Hospital

NCT06489548

ACTIVE NOT RECRUITING NA 41,500 participants

ToolBox Detect: Low Cost Detection of Cognitive Decline in Primary Care Settings

Northwestern University

NCT04852601

ACTIVE NOT RECRUITING 19,114 participants

Aspirin in Reducing Events in the Elderly-Extension (ASPREE-XT)

Anne Murray

NCT07224347

ACTIVE NOT RECRUITING 13,435 participants

Sex-specific Risk Factors and Trajectories of Blood Biomarkers for Alzheimer's Disease and Related Dementias

Anne Murray

NCT07224139

ACTIVE NOT RECRUITING NA 5,043 participants

Changing Talk Online Training (CHATO) National Trial

University of Kansas Medical Center

NCT04610944

ACTIVE NOT RECRUITING NA 3,417 participants

The Brain Health Study: A Pragmatic, Patient-Centered Trial

Kaiser Permanente

NCT05356702

ACTIVE NOT RECRUITING 2,000 participants

Screening for Memory Studies

John Wesson Ashford Jr

NCT01123018

ACTIVE NOT RECRUITING 1,892 participants

Biomarkers for Vascular Contributions to Cognitive Impairment and Dementia Consortium

Massachusetts General Hospital

NCT06284213

ACTIVE NOT RECRUITING Phase 3 1,175 participants

A Study of Different Donanemab (LY3002813) Dosing Regimens in Adults With Early Alzheimer's Disease (TRAILBLAZER-ALZ 6)

Eli Lilly and Company

NCT05738486

ACTIVE NOT RECRUITING 826 participants

The BRAIN Intensive Care Unit (ICU) Study: Bringing to Light the Risk Factors

Vanderbilt University Medical Center

NCT00392795

ACTIVE NOT RECRUITING NA 760 participants

Minnesota Inclusive LTSS for LGBTQ Seniors

University of Minnesota

NCT05530590

ACTIVE NOT RECRUITING 634 participants

Brain Attack Surveillance in Corpus Christi--Cognitive (BASIC-Cognitive)

University of Michigan

NCT03403257

ACTIVE NOT RECRUITING Phase 3 629 participants

ACHIEVE Brain Health Follow-Up Study

Johns Hopkins University

NCT05532657

ACTIVE NOT RECRUITING 600 participants

BRINK (BRain In Kidney Disease) Memory Study 2.0

Anne Murray

NCT04975464

ACTIVE NOT RECRUITING Phase 2 523 participants

A Study of JNJ-63733657 in Participants With Early Alzheimer's Disease

Janssen Research & Development

NCT04619420

ACTIVE NOT RECRUITING Phase 2 490 participants

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation. Master Protocol DIAN-TU-001

Washington University School of Medicine

NCT01760005

ACTIVE NOT RECRUITING 400 participants

Quality Improvement and Clinical Utility PrecivityAD2(TM) Clinician Survey

C2N Diagnostics

NCT06025877

ACTIVE NOT RECRUITING NA 355 participants

A Study of Caregiver Connections Via Technology in Dementia

Mayo Clinic

NCT05779839

ACTIVE NOT RECRUITING Phase 2 350 participants

A Study to Evaluate the Efficacy and Safety of MK-1167 in Participants With Alzheimer's Disease Dementia (MK-1167-008)

Merck Sharp & Dohme

NCT06721156

ACTIVE NOT RECRUITING NA 344 participants

Reducing Risk of Dementia Through Deprescribing

Indiana University

NCT04270474

ACTIVE NOT RECRUITING NA 342 participants

The PorchLight Project

University of Minnesota

NCT05550727

ACTIVE NOT RECRUITING NA 288 participants

PLAN: Dementia Literacy Education and Navigation for Korean Elders With Probable Dementia and Their Caregivers

Johns Hopkins University

NCT03909347

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Phase Distribution

PhaseTrial count
Phase 1 10
Phase 2 19
Phase 3 10
Phase 4 3

Named interventions

Most-linked intervention names on Dementia records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
11 trials
Usual Care Other
3 trials
Limited In-Home Technology Device
2 trials
In-Home Technology System Device
2 trials
Matching Placebo (Remternetug) Drug
2 trials
No interventions Other
2 trials
NeuroElectric StarStim Device
1 trials
Performing Arts Instruction Behavioral
1 trials

US sites by state

Facility locations filed on Dementia trials. A trial with sites in several states counts in each.

California 46 trials
Florida 26 trials
Texas 23 trials
New York 23 trials
North Carolina 19 trials
Maryland 18 trials
Massachusetts 18 trials
Georgia 18 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Dementia page

202 registered trials, 79 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Dementia condition card totals 202 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.