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NCT03761381 · ClinicalTrials.gov registry record
OCT Angiography and NRAI in Dementia
A clinical trial of Alzheimer Disease and Mild Cognitive Impairment, sponsored by Oregon Health and Science University.
- Recruiting
- Registry status
- 20
- Enrollment target
- 1
- Study location
NCT03761381: Recruiting study of Alzheimer Disease and Mild Cognitive Impairment, sponsored by Oregon Health and Science University.
NCT03761381 is a study of Alzheimer Disease and Mild Cognitive Impairment that is actively recruiting participants, run by Oregon Health and Science University. The registered enrollment target is 20 participants, below the 2,751-participant average among 306 other Alzheimer Disease trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03761381, a study of Alzheimer Disease and Mild Cognitive Impairment, is actively recruiting participants, sponsored by Oregon Health and Science University.
- RECRUITING
- Registry status
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
The primary goals of this study are to use optical coherence tomography (OCT) angiography (blood vessel mapping) to: 1. Detect retinal blood vessel and blood flow changes in participants with dementia. 2. Detect amyloid protein deposits in the retinas of participants with dementia.
Primary Outcome
OCT and OCT angiography will be used to detect levels of amyloid proteins deposits within the retina layers on the single enrollment visit only. An increase in the protein detection is expected in the dementia group.
Conditions Studied
Interventions
- DEVICE Optical Coherence Tomography Angiography (OCTA) Imaging
- DEVICE Noninvasive Retinal Amyloid Imaging (NRAI)
Study Locations (1)
Oregon
- Oregon Health & Science University - Portland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2018-09-14 |
| Est. Completion | 2027-12 |
What NCT03761381 shows while recruiting
NCT03761381 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 2,751-participant average among 306 other Alzheimer Disease trials with a reported enrollment target (99% lower).
The record links to 3 conditions, with Alzheimer Disease appearing as the primary indexed condition, and to 2 interventions - of which Optical Coherence Tomography Angiography (OCTA) Imaging is the first listed.
NCT03761381 reports a single indexed study location in Oregon.
Frequently Asked Questions
What is clinical trial NCT03761381 about?
NCT03761381 is a clinical study titled "OCT Angiography and NRAI in Dementia". The primary goals of this study are to use optical coherence tomography (OCT) angiography (blood vessel mapping) to: 1. Detect retinal blood vessel and blood flow changes in participants with dementia. 2. Detect amyloid protein deposits in the retinas of participants with dementia.
What is the current status of trial NCT03761381?
This trial is currently recruiting. The enrollment target is 20 participants. The study started on 2018-09-14. Estimated completion is 2027-12.
What conditions does trial NCT03761381 study?
This clinical trial studies the following conditions: Alzheimer Disease, Mild Cognitive Impairment, Dementia.
What interventions are being tested in trial NCT03761381?
The interventions under investigation include: Optical Coherence Tomography Angiography (OCTA) Imaging (DEVICE), Noninvasive Retinal Amyloid Imaging (NRAI) (DEVICE).
Who is sponsoring clinical trial NCT03761381?
This trial is sponsored by Oregon Health and Science University, which has 546 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03761381 being conducted?
This trial has 1 study location across Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Alzheimer Disease
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03761381's enrollment target sits among peer trials
20 264th of 306 higher than 32 of 306 other Alzheimer Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Alzheimer Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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