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NCT06284213 · ClinicalTrials.gov registry record

Biomarkers for Vascular Contributions to Cognitive Impairment and Dementia Consortium

A clinical trial of Dementia and Cognitive Impairment, sponsored by Massachusetts General Hospital.

Active
Registry status
1,892
Enrollment target
17
Study locations

NCT06284213 is a study of Dementia and Cognitive Impairment that is active but no longer recruiting, run by Massachusetts General Hospital. The registered enrollment target is 1,892 participants, below the 7,713-participant average among 199 other Dementia trials with a reported enrollment target (75% lower). The trial reports 17 study locations across 10 states.

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The verdict

NCT06284213, a study of Dementia and Cognitive Impairment, is active but no longer recruiting, sponsored by Massachusetts General Hospital.

ACTIVE NOT RECRUITING
Registry status
1,892 participants
Enrollment target
17
Study locations

Study Summary

Biomarkers for Vascular Contributions to Cognitive Impairment and Dementia (MarkVCID) is an NIH-funded consortium dedicated to finding biomarkers involved in age-related thinking and memory problems. Alzheimer's disease and other dementias leave signatures on brain scans or in the blood called biomarkers. The MarkVCID study will measure a panel of candidate biomarkers in 1800 participants and watch them closely to see what they tell us about changes in brain function and risk of memory loss. Age-related problems in thinking and memory represent some of the greatest risks to public health in the US and globally. Diseases that affect small blood vessels in the brain have been shown to be major contributors to these changes. However, research and patient care can be held back by limited biomarkers that identify who should be treated. The MarkVCID Consortium includes 17 US medical centers, a Coordinating Center, an External Advisory Committee, and NIH leadership. Data and biospecimens collected as part of this research study will be stored in a research database and biorepositories, so that researchers can use this information to study brain function.

Conditions Studied

Dementia Cognitive Impairment

Interventions

  • OTHER No interventions

Study Locations (17)

California

  • University of Southern California - Los Angeles
  • University of California Los Angeles - Los Angeles
  • University of California Davis - Sacramento
  • University of California San Francisco - San Francisco
  • Olive View - UCLA Medical Center - Sylmar

Texas

  • University of Texas Southwestern - Dallas
  • University of Texas Health Science Center Houston - Houston
  • University of Texas Health Science Center San Antonio - San Antonio

Maryland

  • University of Maryland, Baltimore - Baltimore
  • Johns Hopkins University - Baltimore

Florida

  • Mayo Clinic Florida - Jacksonville

Illinois

  • Rush University Medical Center & Illinois Institute of Technology - Chicago

Kentucky

  • University of Kentucky - Lexington

Minnesota

  • Mayo Clinic Rochester - Rochester

Mississippi

  • University of Mississippi Medical Center - Jackson

Trial Details

FieldValue
Enrollment Target 1,892 participants
Start Date 2021-09-29
Est. Completion 2027-07

Sponsor

Massachusetts General Hospital

2,032 total trials

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What the Registry Record Tells You About NCT06284213

The ClinicalTrials.gov registry entry for NCT06284213 describes a study currently listed as active not recruiting, categorized as an unspecified phase. The registered enrollment target is 1,892 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 7,713-participant average among 199 other Dementia trials with a reported enrollment target (75% lower). The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Dementia appearing as the primary indexed condition, and to 1 intervention - of which No interventions is the first listed.

NCT06284213 reports 17 study locations spanning 10 distinct geographic areas - top geographies include California, Texas, Maryland.

Frequently Asked Questions

What is clinical trial NCT06284213 about?

NCT06284213 is a clinical study titled "Biomarkers for Vascular Contributions to Cognitive Impairment and Dementia Consortium". Biomarkers for Vascular Contributions to Cognitive Impairment and Dementia (MarkVCID) is an NIH-funded consortium dedicated to finding biomarkers involved in age-related thinking and memory problems. Alzheimer's disease and other dementias leave signatures on brain scans or in the blood called bioma...

What is the current status of trial NCT06284213?

This trial is currently active not recruiting. The enrollment target is 1,892 participants. The study started on 2021-09-29. Estimated completion is 2027-07.

What conditions does trial NCT06284213 study?

This clinical trial studies the following conditions: Dementia, Cognitive Impairment.

What interventions are being tested in trial NCT06284213?

The interventions under investigation include: No interventions (OTHER).

Who is sponsoring clinical trial NCT06284213?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06284213 being conducted?

This trial has 17 study locations across California, Florida, Illinois, Kentucky, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.