Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00392795 · ClinicalTrials.gov registry record
The BRAIN Intensive Care Unit (ICU) Study: Bringing to Light the Risk Factors
A clinical trial of Dementia and Delirium, sponsored by Vanderbilt University Medical Center.
- Active
- Registry status
- 826
- Enrollment target
- 2
- Study locations
NCT00392795: Active study of Dementia and Delirium, sponsored by Vanderbilt University Medical Center.
NCT00392795 is a study of Dementia and Delirium that is active but no longer recruiting, run by Vanderbilt University Medical Center. The registered enrollment target is 826 participants, below the 7,719-participant average among 199 other Dementia trials with a reported enrollment target (89% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00392795, a study of Dementia and Delirium, is active but no longer recruiting, sponsored by Vanderbilt University Medical Center.
- ACTIVE NOT RECRUITING
- Registry status
- 826 participants
- Enrollment target
- 2
- Study locations
Study Summary
The primary purpose of this proposal will be to identify potentially modifiable risk factors of long-term cognitive impairment (i.e. development of delirium and exposure to sedative and analgesic medications) in ICU patients. The investigators will quantify the independent contribution of these risk factors to the incidence of long-term cognitive impairment, controlling for other established risk factors including age, pre-existing cognitive impairment, and apolipoprotein E (apoE) genotype. Quantifying the contributions of these modifiable risk factors will pave the way for the development of preventive and/or treatment strategies to reduce the incidence, severity and/or duration of long-term cognitive impairment and improve functional recovery for patients with critical illness.
Conditions Studied
Study Locations (2)
Tennessee
- Saint Thomas Hospital - Nashville
- Vanderbilt University Medical Center - Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 826 participants |
| Start Date | 2007-01 |
| Est. Completion | 2026-12 |
What the registry record for NCT00392795 still lists
NCT00392795 is an observational study that tracks outcomes without assigning an intervention. The registered 826 participants enrollment target is mid-sized for trials with a published cap, below the 7,719-participant average among 199 other Dementia trials with a reported enrollment target (89% lower).
The record links to 3 conditions, with Dementia appearing as the primary indexed condition, and to 0 interventions.
NCT00392795 reports a single indexed study location in Tennessee.
Frequently Asked Questions
What is clinical trial NCT00392795 about?
NCT00392795 is a clinical study titled "The BRAIN Intensive Care Unit (ICU) Study: Bringing to Light the Risk Factors". The primary purpose of this proposal will be to identify potentially modifiable risk factors of long-term cognitive impairment (i.e. development of delirium and exposure to sedative and analgesic medications) in ICU patients. The investigators will quantify the independent contribution of these risk...
What is the current status of trial NCT00392795?
This trial is currently active not recruiting. The enrollment target is 826 participants. The study started on 2007-01. Estimated completion is 2026-12.
What conditions does trial NCT00392795 study?
This clinical trial studies the following conditions: Dementia, Delirium, Cognition Disorders.
Who is sponsoring clinical trial NCT00392795?
This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00392795 being conducted?
This trial has 2 study locations across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Dementia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00392795's enrollment target sits among peer trials
826 36th of 199 higher than 164 of 199 other Dementia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Dementia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Dynamic Light Scattering Ocular Measurement in the Detection of Dementia
RECRUITING
-
Ferritin and Iron Burden in SAH sIRB
RECRUITING · Phase 1
-
δ in Dementia Clinical Trials
RECRUITING · NA
-
Door-Through-Door Companion Rideshare Technology for Individuals With Alzheimer's Disease and Related Dementias (AD/ADRD)
RECRUITING · Phase 1
-
Caregiver as Navigator: Develop Skills Online (CAN-DO)
RECRUITING · NA
-
Clinical Trial Evaluating the Efficacy of AGB101 for Reducing Hippocampal Overactivity in Older Adults
RECRUITING · Phase 2
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT03547973 · 827 participants · Phase 2
Study of Sacituzumab Govitecan in Participants With Urothelial Cancer That Cannot Be Removed or Has Spread
- NCT05630482 · 825 participants · NA
Randomized Trial of Healthy Family Foundations
- NCT06097728 · 825 participants · Phase 3
MEDI5752 in Combination With Carboplatin Plus Pemetrexed in Unresectable Pleural Mesothelioma
- NCT07102641 · 825 participants · Phase 4
Post-cesarean Analgesia: Comparing Effectiveness of Staggered v. Simultaneous Therapies
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia