Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 79 recruiting now official registry

Dementia clinical trials

79 of 202 indexed Dementia trials are currently recruiting.

202 US clinical trials · 79 currently recruiting

Dementia is the subject of 202 registered US clinical trials on ClinicalTrials.gov, 79 of them currently open to new participants. 13 are in Phase 3-4 (later-stage) and 29 in Phase 1-2 (earlier-stage). The most active sponsor is University of Washington, running 8 of these trials.

The research picture

Dementia has 202 registered US clinical trials, 79 of them open to new participants right now, about 39% of the total.

79
recruiting participants now
39%
of trials open to enrollment
13
in Phase 3–4 (later-stage)
8
top sponsor: University of Washington
Phase 110Phase 219Phase 310Phase 43

Active & Recent Trials

202 total, page 3 of 5

ACTIVE NOT RECRUITING NA 270 participants

A Spanish-language Caregiver-Enabled Care Program

Ceresti Health

NCT06631144

ACTIVE NOT RECRUITING NA 250 participants

Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Diet in Stroke Patients Patients

Rush University Medical Center

NCT04337255

ACTIVE NOT RECRUITING NA 200 participants

Supportive Care for Cognitively Impaired Patients and Families

Stanford University

NCT03881579

ACTIVE NOT RECRUITING Phase 2 197 participants

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU)

Washington University School of Medicine

NCT05269394

ACTIVE NOT RECRUITING Phase 3 187 participants

Escitalopram for Agitation in Alzheimer's Disease

JHSPH Center for Clinical Trials

NCT03108846

ACTIVE NOT RECRUITING NA 153 participants

Palliative Care for Patients With Dementia

Icahn School of Medicine at Mount Sinai

NCT05749146

ACTIVE NOT RECRUITING Phase 2 120 participants

Life's End Benefits of cannaBidiol and tetrahYdrocannabinol

University of Southern California

NCT05644262

ACTIVE NOT RECRUITING 100 participants

Plasma Hydrogen Sulfide as a Biomarker for Alzheimer's Disease and Related Dementias

Louisiana State University Health Sciences Center Shreveport

NCT05060848

ACTIVE NOT RECRUITING NA 90 participants

Developing a Communication Intervention for People With Memory Challenges and Their Care Partners

Weill Medical College of Cornell University

NCT05143255

ACTIVE NOT RECRUITING NA 84 participants

Remote Game-based Exercise Program for Cognitive and Motor Function Improvement

University of California, Los Angeles

NCT05235113

ACTIVE NOT RECRUITING Phase 2 70 participants

Preventing Medication Mismanagement in People Living with Dementia Through Automated Medication Dispensing with Facial Recognition and Video Observation

HiDO Technologies

NCT06691256

ACTIVE NOT RECRUITING Phase 2 64 participants

Safety and Modulation of ABCC9 Pathways by Nicorandil for the Treatment of Hippocampal Sclerosis of Aging

Gregory Jicha, MD, PhD

NCT04120766

ACTIVE NOT RECRUITING NA 60 participants

Multi-Center Study of Sensory Stimulation to Improve Brain Function

Cognito Therapeutics

NCT03556280

ACTIVE NOT RECRUITING NA 50 participants

Efficacy of Caregiver Training Program in Enhancing Caregiver and Patient Outcomes

MapHabit

NCT05527405

ACTIVE NOT RECRUITING Phase 3 40 participants

DIAN-TU Amyloid Removal Trial (ART) in Dominantly Inherited Alzheimer's Disease

Washington University School of Medicine

NCT06384573

ACTIVE NOT RECRUITING Phase 1 22 participants

Sirtuin-NAD Activator in Alzheimer's Disease

Brigham and Women's Hospital

NCT05040321

ACTIVE NOT RECRUITING NA 20 participants

Increasing Engagement and Positive Emotional Behavior of Older Adults With Mild-Moderate Dementia With the Use of Motion-Based Technology and Meaningful Activities

Midwestern University

NCT07209124

COMPLETED 336,460 participants

The Effect of De-Prescribing Antipsychotics on Health and Quality of Life for People With Dementia

Columbia University

NCT05172687

COMPLETED NA 47,396 participants

Aligning Patient Preferences: a Role Offering Alzheimer's Patients, Caregivers, and Healthcare Providers Education and Support

Indiana University

NCT03323502

COMPLETED 18,488 participants

Imaging Dementia-Evidence for Amyloid Scanning (IDEAS) Study

American College of Radiology

NCT02420756

COMPLETED 4,884 participants

Genetic Studies in Familial Dementia

University of Miami

NCT04680013

COMPLETED Phase 3 3,069 participants

Ginkgo Biloba Prevention Trial in Older Individuals

National Center for Complementary and Integrative Health (NCCIH)

NCT00010803

COMPLETED NA 2,512 participants

Project to Improve Communication About Serious Illness--Hospital Study: Pragmatic Trial (Trial 1)

University of Washington

NCT04281784

COMPLETED NA 2,176 participants

D-CARE - The Dementia Care Study: A Pragmatic Clinical Trial of Health System-Based Versus Community-Based Dementia Care

University of California, Los Angeles

NCT03786471

COMPLETED NA 989 participants

Aging Brain Care Virtual Program

Indiana University

NCT06245499

COMPLETED 800 participants

MIND-ICU Study: Delirium and Dementia in Veterans Surviving ICU Care

VA Office of Research and Development

NCT00400062

COMPLETED NA 714 participants

Pragmatic Use of PAIN-Advanced Dementia Scale in Emergency Departments

University of Chicago

NCT06370572

COMPLETED 600 participants

Diagnosis and Natural History Study of Patients With Neurological Conditions

National Institute of Neurological Disorders and Stroke (NINDS)

NCT00001549

COMPLETED NA 550 participants

Multidisciplinary Inpatient Palliative Care Intervention

Kaiser Permanente

NCT00325611

COMPLETED NA 510 participants

Reducing Disabilities in Alzheimer's Disease (RDAD) Translation in Area Agencies on Aging (AAAs)

University of Washington

NCT01708304

COMPLETED NA 418 participants

Rural Dementia Caregiver Project

University of California, San Francisco

NCT04428112

COMPLETED 390 participants

fMRI of Vulnerable Brain Regions in Persons at Risk for Alzheimer's Disease

University of Wisconsin, Madison

NCT00478491

COMPLETED Phase 2 376 participants

Rasagiline 1 mg and 2 mg Added to Aricept 10 mg Daily in Patients With Mild to Moderate Alzheimer's Disease (AD)

Teva Branded Pharmaceutical Products R&D

NCT00104273

COMPLETED 366 participants

Quality Improvement PrecivityAD Clinician Survey (QUIP I)

C2N Diagnostics

NCT05477056

COMPLETED NA 355 participants

Enhanced Quality in Primary Care for Elders With Diabetes and Dementia

NYU Langone Health

NCT03723707

COMPLETED NA 342 participants

Comprehensive Home-based Dementia Care Coordination for Medicare-Medicaid Dual Eligibles in Maryland

Johns Hopkins University

NCT02395731

COMPLETED NA 302 participants

Goals of Care: A Nursing Home Trial of Decision Support for Advanced Dementia

University of North Carolina, Chapel Hill

NCT01565642

COMPLETED NA 300 participants

MIND: Care Coordination for Community-living Person With Dementia

Johns Hopkins University

NCT02396082

COMPLETED Phase 1 254 participants

Home Safety Clinical Trial for Alzheimer's Disease

US Department of Veterans Affairs

NCT00459355

COMPLETED 238 participants

Accelerated Non-Atherosclerotic Brain Arterial Aging Relationship to Alzheimer's Disease

Jose Gutierrez, MD, MPH

NCT04510168

COMPLETED NA 234 participants

LifeBio Memory Digital Reminiscence Platform

Benjamin Rose Institute on Aging

NCT04769466

COMPLETED Phase 3 229 participants

Efficacy and Safety of Aricept in the Treatment of Severe Alzheimer's Disease

Eisai

NCT00096473

COMPLETED NA 220 participants

Care Management for Patients With Alzheimer Disease and Their Family Caregivers

Agency for Healthcare Research and Quality (AHRQ)

NCT00246896

COMPLETED 219 participants

Family Caregiver Online Survey (Dementia and Swallowing Difficulties)

University of Oregon

NCT06471660

COMPLETED NA 216 participants

In-Home Technology for Caregivers of People With Dementia and Mild Cognitive Impairment

University of California, Berkeley

NCT04206670

COMPLETED 206 participants

Posterior Cingulate Function in Persons With Risk Factors for Alzheimer's Disease

University of Wisconsin, Madison

NCT00478166

COMPLETED NA 189 participants

Supporting Family Caregivers With Technology for Dementia Home Care

University of Kansas Medical Center

NCT02483520

COMPLETED NA 186 participants

Technology and Family Thriving Study

University of California, Santa Barbara

NCT05150990

COMPLETED NA 182 participants

A Relational Research Recruitment and Engagement Intervention for Cognitive Aging Research

University of Wisconsin, Madison

NCT05444244

COMPLETED NA 175 participants

Life Enhancing Activities for Family Caregivers

University of California, San Francisco

NCT01825681

← Previous Page 3 of 5 Next →

Phase Distribution

PhaseTrial count
Phase 1 10
Phase 2 19
Phase 3 10
Phase 4 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Dementia Trial Landscape

202 indexed Dementia studies · 79 recruiting (39%).

Phase mix: 13 late (III/IV) vs 29 early (I/II).

Top sponsor: University of Washington (8 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Dementia?

PlainTrial tracks 202 US clinical trials for Dementia, of which 79 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Dementia?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.