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Dementia clinical trials
79 of 202 indexed Dementia trials are currently recruiting.
202 US clinical trials · 79 currently recruiting
Dementia is the subject of 202 registered US clinical trials on ClinicalTrials.gov, 79 of them currently open to new participants. 13 are in Phase 3-4 (later-stage) and 29 in Phase 1-2 (earlier-stage). The most active sponsor is University of Washington, running 8 of these trials.
The research picture
Dementia has 202 registered US clinical trials, 79 of them open to new participants right now, about 39% of the total.
- 79
- recruiting participants now
- 39%
- of trials open to enrollment
- 13
- in Phase 3–4 (later-stage)
- 8
- top sponsor: University of Washington
Active & Recent Trials
202 total, page 3 of 5
A Spanish-language Caregiver-Enabled Care Program
Ceresti Health
NCT06631144
Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Diet in Stroke Patients Patients
Rush University Medical Center
NCT04337255
Supportive Care for Cognitively Impaired Patients and Families
Stanford University
NCT03881579
Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU)
Washington University School of Medicine
NCT05269394
Escitalopram for Agitation in Alzheimer's Disease
JHSPH Center for Clinical Trials
NCT03108846
Palliative Care for Patients With Dementia
Icahn School of Medicine at Mount Sinai
NCT05749146
Life's End Benefits of cannaBidiol and tetrahYdrocannabinol
University of Southern California
NCT05644262
Plasma Hydrogen Sulfide as a Biomarker for Alzheimer's Disease and Related Dementias
Louisiana State University Health Sciences Center Shreveport
NCT05060848
Developing a Communication Intervention for People With Memory Challenges and Their Care Partners
Weill Medical College of Cornell University
NCT05143255
Remote Game-based Exercise Program for Cognitive and Motor Function Improvement
University of California, Los Angeles
NCT05235113
Preventing Medication Mismanagement in People Living with Dementia Through Automated Medication Dispensing with Facial Recognition and Video Observation
HiDO Technologies
NCT06691256
Safety and Modulation of ABCC9 Pathways by Nicorandil for the Treatment of Hippocampal Sclerosis of Aging
Gregory Jicha, MD, PhD
NCT04120766
Multi-Center Study of Sensory Stimulation to Improve Brain Function
Cognito Therapeutics
NCT03556280
Efficacy of Caregiver Training Program in Enhancing Caregiver and Patient Outcomes
MapHabit
NCT05527405
DIAN-TU Amyloid Removal Trial (ART) in Dominantly Inherited Alzheimer's Disease
Washington University School of Medicine
NCT06384573
Sirtuin-NAD Activator in Alzheimer's Disease
Brigham and Women's Hospital
NCT05040321
Increasing Engagement and Positive Emotional Behavior of Older Adults With Mild-Moderate Dementia With the Use of Motion-Based Technology and Meaningful Activities
Midwestern University
NCT07209124
The Effect of De-Prescribing Antipsychotics on Health and Quality of Life for People With Dementia
Columbia University
NCT05172687
Aligning Patient Preferences: a Role Offering Alzheimer's Patients, Caregivers, and Healthcare Providers Education and Support
Indiana University
NCT03323502
Imaging Dementia-Evidence for Amyloid Scanning (IDEAS) Study
American College of Radiology
NCT02420756
Genetic Studies in Familial Dementia
University of Miami
NCT04680013
Ginkgo Biloba Prevention Trial in Older Individuals
National Center for Complementary and Integrative Health (NCCIH)
NCT00010803
Project to Improve Communication About Serious Illness--Hospital Study: Pragmatic Trial (Trial 1)
University of Washington
NCT04281784
D-CARE - The Dementia Care Study: A Pragmatic Clinical Trial of Health System-Based Versus Community-Based Dementia Care
University of California, Los Angeles
NCT03786471
Aging Brain Care Virtual Program
Indiana University
NCT06245499
MIND-ICU Study: Delirium and Dementia in Veterans Surviving ICU Care
VA Office of Research and Development
NCT00400062
Pragmatic Use of PAIN-Advanced Dementia Scale in Emergency Departments
University of Chicago
NCT06370572
Diagnosis and Natural History Study of Patients With Neurological Conditions
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00001549
Multidisciplinary Inpatient Palliative Care Intervention
Kaiser Permanente
NCT00325611
Reducing Disabilities in Alzheimer's Disease (RDAD) Translation in Area Agencies on Aging (AAAs)
University of Washington
NCT01708304
Rural Dementia Caregiver Project
University of California, San Francisco
NCT04428112
fMRI of Vulnerable Brain Regions in Persons at Risk for Alzheimer's Disease
University of Wisconsin, Madison
NCT00478491
Rasagiline 1 mg and 2 mg Added to Aricept 10 mg Daily in Patients With Mild to Moderate Alzheimer's Disease (AD)
Teva Branded Pharmaceutical Products R&D
NCT00104273
Quality Improvement PrecivityAD Clinician Survey (QUIP I)
C2N Diagnostics
NCT05477056
Enhanced Quality in Primary Care for Elders With Diabetes and Dementia
NYU Langone Health
NCT03723707
Comprehensive Home-based Dementia Care Coordination for Medicare-Medicaid Dual Eligibles in Maryland
Johns Hopkins University
NCT02395731
Goals of Care: A Nursing Home Trial of Decision Support for Advanced Dementia
University of North Carolina, Chapel Hill
NCT01565642
MIND: Care Coordination for Community-living Person With Dementia
Johns Hopkins University
NCT02396082
Home Safety Clinical Trial for Alzheimer's Disease
US Department of Veterans Affairs
NCT00459355
Accelerated Non-Atherosclerotic Brain Arterial Aging Relationship to Alzheimer's Disease
Jose Gutierrez, MD, MPH
NCT04510168
LifeBio Memory Digital Reminiscence Platform
Benjamin Rose Institute on Aging
NCT04769466
Efficacy and Safety of Aricept in the Treatment of Severe Alzheimer's Disease
Eisai
NCT00096473
Care Management for Patients With Alzheimer Disease and Their Family Caregivers
Agency for Healthcare Research and Quality (AHRQ)
NCT00246896
Family Caregiver Online Survey (Dementia and Swallowing Difficulties)
University of Oregon
NCT06471660
In-Home Technology for Caregivers of People With Dementia and Mild Cognitive Impairment
University of California, Berkeley
NCT04206670
Posterior Cingulate Function in Persons With Risk Factors for Alzheimer's Disease
University of Wisconsin, Madison
NCT00478166
Supporting Family Caregivers With Technology for Dementia Home Care
University of Kansas Medical Center
NCT02483520
Technology and Family Thriving Study
University of California, Santa Barbara
NCT05150990
A Relational Research Recruitment and Engagement Intervention for Cognitive Aging Research
University of Wisconsin, Madison
NCT05444244
Life Enhancing Activities for Family Caregivers
University of California, San Francisco
NCT01825681
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 10 |
| Phase 2 | 19 |
| Phase 3 | 10 |
| Phase 4 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Dementia Trial Landscape
202 indexed Dementia studies · 79 recruiting (39%).
Phase mix: 13 late (III/IV) vs 29 early (I/II).
Top sponsor: University of Washington (8 trials), 9 others listed. 50 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Dementia?
PlainTrial tracks 202 US clinical trials for Dementia, of which 79 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Dementia?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.