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ClinicalTrials.gov 79 recruiting now early-phase tilt #48 of 28,707 conditions

Dementia: early-phase trial registry

79 of 202 indexed Dementia trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #48 of 28,707 conditions by registered trial count.

202 US clinical trials · 79 currently recruiting · #48 of 28,707 conditions by registered trial count

Dementia: 202 US clinical trials tracked, 79 recruiting.

Dementia is the subject of 202 registered US clinical trials on ClinicalTrials.gov, 79 of them currently open to new participants. 13 are in Phase 3-4 (later-stage) and 29 in Phase 1-2 (earlier-stage). The most active sponsor is University of Washington, running 8 of these trials.

Enrollment posture brief

Registry condition dementia

OPEN 79 | RECR 39% | LATE 13 | EARLY 29 | RANK #48 | SPON 8

Nearest open-share peer: Advanced Non-Small-Cell Lung Cancer (39% recruiting · 23 trials)

Spinal Cord Injuries53.2%Glioblastoma39%Dementia (this)39%Atrial Fibrillation29.4%Rheumatoid Arthritis18.6%
Open-enrollment share among volume-matched conditions near Dementia

Dementia lists 79 open slots (39% of 202 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Dementia on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Dementia is recruiting above its size-band peers.

    79 of 202 indexed trials (39.1%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Dementia trials is spread across many organizations.

    University of Washington accounts for 8 of 202 trials (4%). 110 distinct sponsors appear on at least one study for this condition label.

  3. Typical Dementia enrolment sits around 154 participants.

    Median target enrolment is 154 among the 200 trials that report a genuine target (sentinel values excluded). 80 of those (40%) plan for fewer than 100 participants.

  4. Dementia research is mostly interventional.

    157 interventional and 45 observational studies make up this index (77.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 110Phase 219Phase 310Phase 43

Open and recent trials

202 total, page 3 of 5

ACTIVE NOT RECRUITING NA 270 participants

A Spanish-language Caregiver-Enabled Care Program

Ceresti Health

NCT06631144

ACTIVE NOT RECRUITING NA 250 participants

Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Diet in Stroke Patients Patients

Rush University Medical Center

NCT04337255

ACTIVE NOT RECRUITING NA 200 participants

Supportive Care for Cognitively Impaired Patients and Families

Stanford University

NCT03881579

ACTIVE NOT RECRUITING Phase 2 197 participants

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU)

Washington University School of Medicine

NCT05269394

ACTIVE NOT RECRUITING Phase 3 187 participants

Escitalopram for Agitation in Alzheimer's Disease

JHSPH Center for Clinical Trials

NCT03108846

ACTIVE NOT RECRUITING NA 153 participants

Palliative Care for Patients With Dementia

Icahn School of Medicine at Mount Sinai

NCT05749146

ACTIVE NOT RECRUITING Phase 2 120 participants

Life's End Benefits of cannaBidiol and tetrahYdrocannabinol

University of Southern California

NCT05644262

ACTIVE NOT RECRUITING 100 participants

Plasma Hydrogen Sulfide as a Biomarker for Alzheimer's Disease and Related Dementias

Louisiana State University Health Sciences Center Shreveport

NCT05060848

ACTIVE NOT RECRUITING NA 90 participants

Developing a Communication Intervention for People With Memory Challenges and Their Care Partners

Weill Medical College of Cornell University

NCT05143255

ACTIVE NOT RECRUITING NA 84 participants

Remote Game-based Exercise Program for Cognitive and Motor Function Improvement

University of California, Los Angeles

NCT05235113

ACTIVE NOT RECRUITING Phase 2 70 participants

Preventing Medication Mismanagement in People Living with Dementia Through Automated Medication Dispensing with Facial Recognition and Video Observation

HiDO Technologies

NCT06691256

ACTIVE NOT RECRUITING Phase 2 64 participants

Safety and Modulation of ABCC9 Pathways by Nicorandil for the Treatment of Hippocampal Sclerosis of Aging

Gregory Jicha, MD, PhD

NCT04120766

ACTIVE NOT RECRUITING NA 60 participants

Multi-Center Study of Sensory Stimulation to Improve Brain Function

Cognito Therapeutics

NCT03556280

ACTIVE NOT RECRUITING NA 50 participants

Efficacy of Caregiver Training Program in Enhancing Caregiver and Patient Outcomes

MapHabit

NCT05527405

ACTIVE NOT RECRUITING Phase 3 40 participants

DIAN-TU Amyloid Removal Trial (ART) in Dominantly Inherited Alzheimer's Disease

Washington University School of Medicine

NCT06384573

ACTIVE NOT RECRUITING Phase 1 22 participants

Sirtuin-NAD Activator in Alzheimer's Disease

Brigham and Women's Hospital

NCT05040321

ACTIVE NOT RECRUITING NA 20 participants

Increasing Engagement and Positive Emotional Behavior of Older Adults With Mild-Moderate Dementia With the Use of Motion-Based Technology and Meaningful Activities

Midwestern University

NCT07209124

COMPLETED 336,460 participants

The Effect of De-Prescribing Antipsychotics on Health and Quality of Life for People With Dementia

Columbia University

NCT05172687

COMPLETED NA 47,396 participants

Aligning Patient Preferences: a Role Offering Alzheimer's Patients, Caregivers, and Healthcare Providers Education and Support

Indiana University

NCT03323502

COMPLETED 18,488 participants

Imaging Dementia-Evidence for Amyloid Scanning (IDEAS) Study

American College of Radiology

NCT02420756

COMPLETED 4,884 participants

Genetic Studies in Familial Dementia

University of Miami

NCT04680013

COMPLETED Phase 3 3,069 participants

Ginkgo Biloba Prevention Trial in Older Individuals

National Center for Complementary and Integrative Health (NCCIH)

NCT00010803

COMPLETED NA 2,512 participants

Project to Improve Communication About Serious Illness--Hospital Study: Pragmatic Trial (Trial 1)

University of Washington

NCT04281784

COMPLETED NA 2,176 participants

D-CARE - The Dementia Care Study: A Pragmatic Clinical Trial of Health System-Based Versus Community-Based Dementia Care

University of California, Los Angeles

NCT03786471

COMPLETED NA 989 participants

Aging Brain Care Virtual Program

Indiana University

NCT06245499

COMPLETED 800 participants

MIND-ICU Study: Delirium and Dementia in Veterans Surviving ICU Care

VA Office of Research and Development

NCT00400062

COMPLETED NA 714 participants

Pragmatic Use of PAIN-Advanced Dementia Scale in Emergency Departments

University of Chicago

NCT06370572

COMPLETED 600 participants

Diagnosis and Natural History Study of Patients With Neurological Conditions

National Institute of Neurological Disorders and Stroke (NINDS)

NCT00001549

COMPLETED NA 550 participants

Multidisciplinary Inpatient Palliative Care Intervention

Kaiser Permanente

NCT00325611

COMPLETED NA 510 participants

Reducing Disabilities in Alzheimer's Disease (RDAD) Translation in Area Agencies on Aging (AAAs)

University of Washington

NCT01708304

COMPLETED NA 418 participants

Rural Dementia Caregiver Project

University of California, San Francisco

NCT04428112

COMPLETED 390 participants

fMRI of Vulnerable Brain Regions in Persons at Risk for Alzheimer's Disease

University of Wisconsin, Madison

NCT00478491

COMPLETED Phase 2 376 participants

Rasagiline 1 mg and 2 mg Added to Aricept 10 mg Daily in Patients With Mild to Moderate Alzheimer's Disease (AD)

Teva Branded Pharmaceutical Products R&D

NCT00104273

COMPLETED 366 participants

Quality Improvement PrecivityAD Clinician Survey (QUIP I)

C2N Diagnostics

NCT05477056

COMPLETED NA 355 participants

Enhanced Quality in Primary Care for Elders With Diabetes and Dementia

NYU Langone Health

NCT03723707

COMPLETED NA 342 participants

Comprehensive Home-based Dementia Care Coordination for Medicare-Medicaid Dual Eligibles in Maryland

Johns Hopkins University

NCT02395731

COMPLETED NA 302 participants

Goals of Care: A Nursing Home Trial of Decision Support for Advanced Dementia

University of North Carolina, Chapel Hill

NCT01565642

COMPLETED NA 300 participants

MIND: Care Coordination for Community-living Person With Dementia

Johns Hopkins University

NCT02396082

COMPLETED Phase 1 254 participants

Home Safety Clinical Trial for Alzheimer's Disease

US Department of Veterans Affairs

NCT00459355

COMPLETED 238 participants

Accelerated Non-Atherosclerotic Brain Arterial Aging Relationship to Alzheimer's Disease

Jose Gutierrez, MD, MPH

NCT04510168

COMPLETED NA 234 participants

LifeBio Memory Digital Reminiscence Platform

Benjamin Rose Institute on Aging

NCT04769466

COMPLETED Phase 3 229 participants

Efficacy and Safety of Aricept in the Treatment of Severe Alzheimer's Disease

Eisai

NCT00096473

COMPLETED NA 220 participants

Care Management for Patients With Alzheimer Disease and Their Family Caregivers

Agency for Healthcare Research and Quality (AHRQ)

NCT00246896

COMPLETED 219 participants

Family Caregiver Online Survey (Dementia and Swallowing Difficulties)

University of Oregon

NCT06471660

COMPLETED NA 216 participants

In-Home Technology for Caregivers of People With Dementia and Mild Cognitive Impairment

University of California, Berkeley

NCT04206670

COMPLETED 206 participants

Posterior Cingulate Function in Persons With Risk Factors for Alzheimer's Disease

University of Wisconsin, Madison

NCT00478166

COMPLETED NA 189 participants

Supporting Family Caregivers With Technology for Dementia Home Care

University of Kansas Medical Center

NCT02483520

COMPLETED NA 186 participants

Technology and Family Thriving Study

University of California, Santa Barbara

NCT05150990

COMPLETED NA 182 participants

A Relational Research Recruitment and Engagement Intervention for Cognitive Aging Research

University of Wisconsin, Madison

NCT05444244

COMPLETED NA 175 participants

Life Enhancing Activities for Family Caregivers

University of California, San Francisco

NCT01825681

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Phase Distribution

PhaseTrial count
Phase 1 10
Phase 2 19
Phase 3 10
Phase 4 3

Named interventions

Most-linked intervention names on Dementia records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
11 trials
Usual Care Other
3 trials
Limited In-Home Technology Device
2 trials
In-Home Technology System Device
2 trials
Matching Placebo (Remternetug) Drug
2 trials
No interventions Other
2 trials
NeuroElectric StarStim Device
1 trials
Performing Arts Instruction Behavioral
1 trials

US sites by state

Facility locations filed on Dementia trials. A trial with sites in several states counts in each.

California 46 trials
Florida 26 trials
Texas 23 trials
New York 23 trials
North Carolina 19 trials
Maryland 18 trials
Massachusetts 18 trials
Georgia 18 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Dementia page

202 registered trials, 79 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Dementia condition card totals 202 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.