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ClinicalTrials.gov 79 recruiting now early-phase tilt #48 of 28,707 conditions

Dementia: early-phase trial registry

79 of 202 indexed Dementia trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #48 of 28,707 conditions by registered trial count.

202 US clinical trials · 79 currently recruiting · #48 of 28,707 conditions by registered trial count

Dementia: 202 US clinical trials tracked, 79 recruiting.

Dementia is the subject of 202 registered US clinical trials on ClinicalTrials.gov, 79 of them currently open to new participants. 13 are in Phase 3-4 (later-stage) and 29 in Phase 1-2 (earlier-stage). The most active sponsor is University of Washington, running 8 of these trials.

Enrollment posture brief

Registry condition dementia

OPEN 79 | RECR 39% | LATE 13 | EARLY 29 | RANK #48 | SPON 8

Nearest open-share peer: Advanced Non-Small-Cell Lung Cancer (39% recruiting · 23 trials)

Spinal Cord Injuries53.2%Glioblastoma39%Dementia (this)39%Atrial Fibrillation29.4%Rheumatoid Arthritis18.6%
Open-enrollment share among volume-matched conditions near Dementia

Dementia lists 79 open slots (39% of 202 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Dementia on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Dementia is recruiting above its size-band peers.

    79 of 202 indexed trials (39.1%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Dementia trials is spread across many organizations.

    University of Washington accounts for 8 of 202 trials (4%). 110 distinct sponsors appear on at least one study for this condition label.

  3. Typical Dementia enrolment sits around 154 participants.

    Median target enrolment is 154 among the 200 trials that report a genuine target (sentinel values excluded). 80 of those (40%) plan for fewer than 100 participants.

  4. Dementia research is mostly interventional.

    157 interventional and 45 observational studies make up this index (77.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 110Phase 219Phase 310Phase 43

Open and recent trials

202 total, page 1 of 5

RECRUITING 500,000 participants

Alzheimer's Prevention Registry: A Program to Accelerate Enrollment Into Studies

Banner Health

NCT02022943

RECRUITING 200,000 participants

Alzheimer Prevention Trials (APT) Webstudy

University of Southern California

NCT03638583

RECRUITING NA 180,000 participants

TabCAT Brain Health Assessment in Primary Care

University of California, San Francisco

NCT06090578

RECRUITING NA 45,257 participants

Primary Care Detection of Cognitive Impairment Leveraging Health & Consumer Technologies in Underserved Communities: The MyCog Trial

Northwestern University

NCT05607732

RECRUITING Phase 4 20,000 participants

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

Duke University

NCT04262206

RECRUITING 12,000 participants

Genetic Characterization of Movement Disorders and Dementias

National Institute on Aging (NIA)

NCT02014246

RECRUITING 10,000 participants

Alzheimer's Disease Genetics Study

Indiana University

NCT00064870

RECRUITING 10,000 participants

NYSCF Scientific Discovery Biobank

New York Stem Cell Foundation Research Institute

NCT06203106

RECRUITING NA 6,600 participants

5-Cog 2.0: A Pragmatic Clinical Trial

Albert Einstein College of Medicine

NCT05515224

RECRUITING NA 5,000 participants

Clinical Applications of Advanced Ophthalmic Imaging

University of Miami

NCT03135327

RECRUITING 2,000 participants

Phase I Human Analytics (HALO) Study

HALO Diagnostics

NCT05423860

RECRUITING NA 2,000 participants

The INSPIRE Study: Intervention Strategies for Preserving Intellectual Resilience and Engagement

Healthy Minds Initiative

NCT06741865

RECRUITING 2,000 participants

Alzheimer's Disease Treatment With Combination of 40Hz Light and Cognitive Therapy

Alzheimer's Light

NCT03657745

RECRUITING NA 1,800 participants

Promoting Goals-of-Care Discussions for Patients With Memory Problems and Their Caregivers

University of Washington

NCT05596760

RECRUITING 1,800 participants

Study to Understand Novel Biomarkers in Researching Dementia

Washington University School of Medicine

NCT06547099

RECRUITING NA 1,764 participants

Evaluating a National Person-Centered Training Program to Strengthen the Dementia Care Workforce

University of North Carolina, Chapel Hill

NCT06239688

RECRUITING NA 1,305 participants

The Active Mind Trial: An Adaptive Randomized Trial to Improve Function and Delay Dementia

University of Alabama at Birmingham

NCT04171323

RECRUITING 1,000 participants

DC Longitudinal Study on Aging and Specimen Bank

Georgetown University

NCT03702907

RECRUITING 1,000 participants

Tennessee Alzheimer's Project

Vanderbilt University Medical Center

NCT05372172

RECRUITING NA 750 participants

Trial to Reduce Antimicrobial Use in Nursing Home Residents With Alzheimer's Disease and Other Dementias 2.0

Hebrew SeniorLife

NCT05950607

RECRUITING 520 participants

Paradoxical Lucidity in Severe End-Stage Dementia

NYU Langone Health

NCT05234866

RECRUITING 500 participants

ADRC Clinical Cohort (Alzheimer's Disease)

Duke University

NCT06703541

RECRUITING NA 456 participants

Enhancing Sleep Quality for Nursing Home Residents With Dementia - R33 Phase

University of Alabama, Tuscaloo

NCT05820919

RECRUITING 450 participants

Trial-Ready Cohort-Down Syndrome (TRC-DS)

University of Southern California

NCT04165109

RECRUITING NA 440 participants

Evaluating the Efficacy of the Pain Identification and Communication Toolkit

Weill Medical College of Cornell University

NCT06168604

RECRUITING NA 400 participants

Dementia and Diabetes Prevention Program

University of California, Davis

NCT04141878

RECRUITING NA 388 participants

Anxiety Sensitivity Treatment to Reduce Anxiety in Alzheimer's

Florida State University

NCT05748613

RECRUITING NA 360 participants

Connect-Home: Alzheimer's Disease and Related Dementias

University of North Carolina, Chapel Hill

NCT06840587

RECRUITING 360 participants

Persons With Dementia and Their Extended Family Caregivers

Karen Roberto

NCT04863859

RECRUITING NA 300 participants

Enhancing Triadic Communication About Cognition for Older Adults With Alzheimer's Disease or Related Dementias Facing a Cancer Management Decision

University of Rochester

NCT06313853

RECRUITING NA 300 participants

HEARS-NPS: Addressing Hearing Loss as a Common Unmet Contributor of Neuropsychiatric Symptoms

Johns Hopkins University

NCT06930560

RECRUITING Phase 2 300 participants

Testing the Pain Clinical Practice Guideline

University of Maryland, Baltimore

NCT05858996

RECRUITING Phase 2 280 participants

A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

Washington University School of Medicine

NCT06647498

RECRUITING Phase 2 280 participants

A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

Washington University School of Medicine

NCT05552157

RECRUITING NA 270 participants

Caregiver as Navigator: Develop Skills Online (CAN-DO)

Emory University

NCT06177990

RECRUITING NA 266 participants

Coaching Dementia Caregivers to Master Care-Resistant Behavior

University of Alabama at Birmingham

NCT05098652

RECRUITING NA 200 participants

δ in Dementia Clinical Trials

The University of Texas Health Science Center at San Antonio

NCT05592678

RECRUITING NA 200 participants

Learning Skills Together Family Caregiver Complex Intervention

Case Western Reserve University

NCT05846984

RECRUITING NA 200 participants

Dementia Caregivers' Link to Assistance and Resources

Visiting Nurse Service of New York

NCT06860035

RECRUITING Phase 1 184 participants

PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease

National Institute of Mental Health (NIMH)

NCT04396873

RECRUITING 150 participants

Sleep and Circadian Rhythm Biomarkers of Postoperative Delirium

Massachusetts General Hospital

NCT06052397

RECRUITING NA 144 participants

Non-invasive Brain Stimulation for Cognitive and Motor Dysfunction in Dementia

Hebrew SeniorLife

NCT05661084

RECRUITING NA 128 participants

Dementia Care Partner Hospital Assessment Tool

University of Wisconsin, Madison

NCT05592366

RECRUITING Phase 1 120 participants

Door-Through-Door Companion Rideshare Technology for Individuals With Alzheimer's Disease and Related Dementias (AD/ADRD)

Onward Health

NCT06850870

RECRUITING NA 120 participants

Improving PCP Advance Care Planning for People With ADRD

University of Pittsburgh

NCT06565169

RECRUITING Early Phase 1 120 participants

Educational Support Group Program for Bilingual and Spanish-speaking Carepartners and People With Progressive Aphasia

University of Texas at Austin

NCT06511752

RECRUITING NA 120 participants

The BRAIN App (Phase 2 SBIR)

Hopeful Aging

NCT06298474

RECRUITING NA 118 participants

Effect of Cognitive Empathy Training on Dementia Caregivers

Emory University

NCT06650527

RECRUITING Phase 1 102 participants

First-in-Human Evaluation of an Astrocytic Glutamate Transporter (EAAT2) PET Tracer in Dementia

David Wilson

NCT05374278

RECRUITING NA 100 participants

NiteCAPP: Web-based Interventions for Insomnia in Rural Dementia Caregivers

University of South Florida

NCT04896775

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Phase Distribution

PhaseTrial count
Phase 1 10
Phase 2 19
Phase 3 10
Phase 4 3

Named interventions

Most-linked intervention names on Dementia records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
11 trials
Usual Care Other
3 trials
Limited In-Home Technology Device
2 trials
In-Home Technology System Device
2 trials
Matching Placebo (Remternetug) Drug
2 trials
No interventions Other
2 trials
NeuroElectric StarStim Device
1 trials
Performing Arts Instruction Behavioral
1 trials

US sites by state

Facility locations filed on Dementia trials. A trial with sites in several states counts in each.

California 46 trials
Florida 26 trials
Texas 23 trials
New York 23 trials
North Carolina 19 trials
Maryland 18 trials
Massachusetts 18 trials
Georgia 18 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Dementia page

202 registered trials, 79 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Dementia condition card totals 202 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.