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NCT04692441 · ClinicalTrials.gov registry record · NA

Apolipoprotein E (APOE) Genotype Effects on Triglycerides and Blood Flow in the Human Brain

A NA study of Alzheimer Disease and Dementia, sponsored by University of Washington.

Recruiting
Registry status
NA
Development phase
90
Enrollment target
1
Study location

NCT04692441 is a NA study of Alzheimer Disease and Dementia that is actively recruiting participants, run by University of Washington. The registered enrollment target is 90 participants, below the 2,750-participant average among 306 other Alzheimer Disease trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT04692441, a NA study of Alzheimer Disease and Dementia, is actively recruiting participants, sponsored by University of Washington.

RECRUITING
Registry status
NA
Development phase
90 participants
Enrollment target
1
Study location

Study Summary

High fat feeding (HFF) increases the risk of Alzheimer's disease (AD) but individuals who carry the AD risk gene E4 paradoxically improve after acute HFF. The investigators propose to further study this phenomenon with a clinical study to assess cerebral blood flow which can be measured by a technique called arterial spin labeling (ASL) on an MRI and is tightly related to brain metabolism.

Conditions Studied

Alzheimer Disease Dementia

Interventions

  • DIETARY_SUPPLEMENT Heavy Cream

Study Locations (1)

Washington

  • University of Washington Medical Center - Seattle

Trial Details

FieldValue
Enrollment Target 90 participants
Start Date 2021-05-01
Est. Completion 2025-12-31
Phase NA

Sponsor

University of Washington

1,048 total trials

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What the Registry Record Tells You About NCT04692441

The ClinicalTrials.gov registry entry for NCT04692441 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 90 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,750-participant average among 306 other Alzheimer Disease trials with a reported enrollment target (97% lower). The listed sponsor is University of Washington, which has 1,048 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Alzheimer Disease appearing as the primary indexed condition, and to 1 intervention - of which Heavy Cream is the first listed.

NCT04692441 reports 1 study location spanning 1 distinct geographic area - top geographies include Washington.

Frequently Asked Questions

What is clinical trial NCT04692441 about?

NCT04692441 is a clinical study titled "Apolipoprotein E (APOE) Genotype Effects on Triglycerides and Blood Flow in the Human Brain". High fat feeding (HFF) increases the risk of Alzheimer's disease (AD) but individuals who carry the AD risk gene E4 paradoxically improve after acute HFF. The investigators propose to further study this phenomenon with a clinical study to assess cerebral blood flow which can be measured by a techniq...

What is the current status of trial NCT04692441?

This trial is currently recruiting. It is a NA study. The enrollment target is 90 participants. The study started on 2021-05-01. Estimated completion is 2025-12-31.

What conditions does trial NCT04692441 study?

This clinical trial studies the following conditions: Alzheimer Disease, Dementia.

What interventions are being tested in trial NCT04692441?

The interventions under investigation include: Heavy Cream (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT04692441?

This trial is sponsored by University of Washington, which has 1,048 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04692441 being conducted?

This trial has 1 study location across Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.