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ClinicalTrials.gov 108 recruiting now early-phase tilt #47 of 28,707 conditions

Spinal Cord Injuries: early-phase trial registry

108 of 203 indexed Spinal Cord Injuries trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #47 of 28,707 conditions by registered trial count.

203 US clinical trials · 108 currently recruiting · #47 of 28,707 conditions by registered trial count

Spinal Cord Injuries: 203 US clinical trials tracked, 108 recruiting.

Spinal Cord Injuries is the subject of 203 registered US clinical trials on ClinicalTrials.gov, 108 of them currently open to new participants. 5 are in Phase 3-4 (later-stage) and 26 in Phase 1-2 (earlier-stage). The most active sponsor is University of Louisville, running 9 of these trials.

Enrollment posture brief

Registry condition spinal-cord-injuries

OPEN 108 | RECR 53% | LATE 5 | EARLY 26 | RANK #47 | SPON 9

Nearest open-share peer: Malignant Solid Neoplasm (53% recruiting · 177 trials)

Spinal Cord Injuries (this)53%Mild Cognitive Impairment48.5%Dementia39.1%Glioblastoma39%Atrial Fibrillation29.4%
Open-enrollment share among volume-matched conditions near Spinal Cord Injuries

Spinal Cord Injuries lists 108 open slots (53% of 203 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Spinal Cord Injuries on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Spinal Cord Injuries is recruiting above its size-band peers.

    108 of 203 indexed trials (53.2%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Spinal Cord Injuries trials is spread across many organizations.

    University of Louisville accounts for 9 of 203 trials (4.4%). 83 distinct sponsors appear on at least one study for this condition label.

  3. Most Spinal Cord Injuries trials plan to enrol fewer than 100 people.

    Median target enrolment is 30 among the 203 trials that report a genuine target (sentinel values excluded). 170 of those (83.7%) plan for fewer than 100 participants.

  4. Spinal Cord Injuries research is mostly interventional.

    180 interventional and 23 observational studies make up this index (88.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 112Phase 214Phase 32Phase 43

Open and recent trials

203 total, page 1 of 5

RECRUITING NA 764 participants

Human-like Robotic Controllers for Enhanced Motor Learning

Shirley Ryan AbilityLab

NCT04578665

RECRUITING NA 250 participants

Spinal Cord Injury Model Systems (SCIMS) - Education Module

University of Miami

NCT06003686

RECRUITING NA 250 participants

Virtual Walking Intervention for Neuropathic Pain in Spinal Cord Injury

Texas A&M University

NCT05005026

RECRUITING NA 228 participants

Hemodynamic Management Following Acute Traumatic Spinal Cord Injury

The University of Texas Health Science Center, Houston

NCT06451133

RECRUITING 200 participants

Effectiveness of the Collaborative Community Clinic for Persons With Spinal Cord Injury and Disease

Washington University School of Medicine

NCT04457206

RECRUITING Phase 2 196 participants

Using Smartphones to Improve Physical Activity Levels of Individuals With Spinal Cord Injury

Temple University

NCT05317832

RECRUITING 160 participants

AIM's Writing for Healing: A Workshop for Individuals Living With Paralysis

University of Alabama at Birmingham

NCT04721717

RECRUITING NA 160 participants

Mobile Health Self-Management and Support System for Chronic and Complex Health Conditions

University of Pittsburgh

NCT02592291

RECRUITING NA 144 participants

Dosing of Overground Robotic Gait Training with Functional Outcomes and Neuroplasticity After Spinal Cord Injury

Baylor Research Institute

NCT05218447

RECRUITING 140 participants

SCIVAX: Biomarkers of Immune Dysfunction and Vaccine Responsiveness in Chronic SCI

Northwell Health

NCT05869968

RECRUITING NA 120 participants

Transcutaneous Tibial Nerve Stimulation for Spinal Cord Injury Neurogenic Bladder

The University of Texas Health Science Center, Houston

NCT04350359

RECRUITING Phase 2 120 participants

Intravesical LGG VS Saline Bladder Wash RCT

Medstar Health Research Institute

NCT05230511

RECRUITING NA 120 participants

Spinal Cord Stimulation and Training

Washington University School of Medicine

NCT05472584

RECRUITING NA 108 participants

Promoting Recovery Outcomes Through Precise Early Locomotor Interventions in Persons With Spinal Cord Injury

Milap Sandhu

NCT06176833

RECRUITING NA 100 participants

Epidural Stimulation After Neurologic Damage

University of Minnesota

NCT03026816

RECRUITING NA 100 participants

Non-invasive BCI-controlled Assistive Devices

University of Texas at Austin

NCT05183152

RECRUITING NA 96 participants

Telenutrition for Individuals With SCI

Santa Clara Valley Health & Hospital System

NCT05468437

RECRUITING NA 80 participants

Acute and Chronic Repercussion of Spinal Cord Stimulation After Spinal Cord Injury

Mayo Clinic

NCT07210411

RECRUITING 80 participants

Development of a Novel Evaluation Scale of Mental Body Representation (MBR) for Adults With Spinal Cord Injury

University of Minnesota

NCT07029802

RECRUITING NA 69 participants

Deciphering Preserved Autonomic Function After Spinal Cord Injury

Mayo Clinic

NCT04493372

RECRUITING NA 62 participants

BioFLO for Respiratory Recovery in SCI

University of Florida

NCT06011876

RECRUITING 60 participants

Role of Endothelial Function in SCI CVD Risk

Craig Hospital

NCT06443151

RECRUITING 60 participants

Patient and Caregiver Perspectives on Intravesical Instillations for Urinary Symptoms

Medstar Health Research Institute

NCT07390591

RECRUITING NA 60 participants

Harnessing Neuroplasticity of Postural Sensorimotor Networks Using Non-Invasive Spinal Neuromodulation to Maximize Functional Recovery After Spinal Cord Injury

The Methodist Hospital Research Institute

NCT06213012

RECRUITING NA 60 participants

Combination Therapy to Improve SCI Recovery.

Spaulding Rehabilitation Hospital

NCT05563103

RECRUITING NA 60 participants

The Impact of Expressive Emotional Writing on Facilitating Grief Resolution in Adults With Spinal Cord Injury

University of Alabama at Birmingham

NCT06147258

RECRUITING NA 60 participants

Low Oxygen Therapy to Enhance Walking Recovery After SCI.

Spaulding Rehabilitation Hospital

NCT06521723

RECRUITING NA 60 participants

Ketogenic Diet to Improve Neuro-recovery

Ohio State University

NCT03509571

RECRUITING NA 60 participants

Upper Extremity Functional Electrical Stimulation (FES) for Restoration of Upper Extremity Function After Spinal Cord Injury (SCI)

University of Miami

NCT06672458

RECRUITING NA 60 participants

ARC-IM System to Manage Symptomatic Blood Pressure Instability Secondary to Chronic Spinal Cord Injury

ONWARD Medical

NCT07147296

RECRUITING NA 50 participants

Safety, Feasibility, and Efficacy of TSCS on Stabilizing Blood Pressure for Acute Inpatients With SCI

Jill M. Wecht, Ed.D.

NCT06000592

RECRUITING Phase 4 50 participants

Glycemic and Weight Loss Effects of GLP-1R Agonist Therapy in Subjects With Spinal Cord Injury and Type 2 Diabetes

Marzieh Salehi

NCT06706284

RECRUITING NA 50 participants

Improving Adherence to Spinal Cord Injury Exercise Guidelines Using Smartphone Technology and E-coaching

Shirley Ryan AbilityLab

NCT05424172

RECRUITING NA 49 participants

Eccentric Muscle Training, Stimulation, and Biomarkers in SCI

Ohio State University

NCT05337982

RECRUITING 48 participants

Testosterone Deficiency and Endothelial Dysfunction After Spinal Cord Injury

Craig Hospital

NCT07227740

RECRUITING NA 48 participants

Virtual Walking Therapy for Neuropathic Pain Following Incomplete Spinal Cord Injury

Texas A&M University

NCT06330181

RECRUITING NA 44 participants

Effects of Breathing Mild Bouts of Low Oxygen on Limb Mobility After Spinal Injury

Spaulding Rehabilitation Hospital

NCT02323945

RECRUITING Phase 4 42 participants

Feasibility of Early Gabapentin as an Intervention for Neurorecovery

MetroHealth Medical Center

NCT05302999

RECRUITING NA 40 participants

HAPPINESS: cHAnging the Perceived Pain INtEnSity in Populations With Spinal Cord Injury and With Health Disparities: A Feasibility Study

University of Minnesota

NCT06140355

RECRUITING NA 40 participants

Physical Therapy Wound Care Modalities in Patients With Spinal Cord Injury (SCI)

Wake Forest University Health Sciences

NCT05458947

RECRUITING NA 40 participants

Mild Intermittent Hypoxia and Its Multipronged Effect on Sleep Apnea

Wayne State University

NCT03736382

RECRUITING Phase 1 40 participants

NVG-291 in Spinal Cord Injury Subjects

NervGen Pharma

NCT05965700

RECRUITING NA 40 participants

MyHand-SCI: An Active Hand Orthosis for Spinal Cord Injury

Columbia University

NCT05553457

RECRUITING 40 participants

Endothelial Dysfunction After SCI

Craig Hospital

NCT07227727

RECRUITING NA 36 participants

Spinal Cord Stimulation for Respiratory Rehabilitation in Patients With Chronic Spinal Cord Injury

University of Louisville

NCT06019949

RECRUITING NA 36 participants

Upper Extremity Training for Chronic Cervical Spinal Cord Injury

Kessler Foundation

NCT04921592

RECRUITING NA 36 participants

Influence of Spinal Stimulation Frequency on Spasticity, Motor Control, and Pain After Spinal Cord Injury

Shepherd Center, Atlanta GA

NCT06214208

RECRUITING NA 36 participants

Task-specific Epidural Stimulation Study

University of Louisville

NCT03364660

RECRUITING NA 36 participants

Nomad P-KAFO Study

Shirley Ryan AbilityLab

NCT05644522

RECRUITING Phase 1 36 participants

Novel Soluble Epoxide Hydrolase Inhibitor for Neuropathic Pain in Patients With Spinal Cord Injury

EicOsis Human Health

NCT06438471

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Phase Distribution

PhaseTrial count
Phase 1 12
Phase 2 14
Phase 3 2
Phase 4 3

Named interventions

Most-linked intervention names on Spinal Cord Injuries records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
5 trials
Tests of sympathetic inhibition Diagnostic test
3 trials
Transcutaneous spinal stimulation Device
3 trials
Placebo Other
3 trials
BrainGate Neural Interface System Device
3 trials
I-Box by Dynatronics Device
2 trials
Combination of Neostigmine and Glycopyrrolate Drug
2 trials
Transcutaneous Spinal Cord Stimulation Device
2 trials

US sites by state

Facility locations filed on Spinal Cord Injuries trials. A trial with sites in several states counts in each.

Texas 26 trials
New York 23 trials
Florida 23 trials
California 17 trials
Massachusetts 15 trials
Illinois 14 trials
Pennsylvania 13 trials
New Jersey 13 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Spinal Cord Injuries page

203 registered trials, 108 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Spinal Cord Injuries condition card totals 203 registered trials; most-linked intervention Placebo; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.