Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

2026 data Public-data reference. official source

Cannabis Use

Open-data reference.

45 US clinical trials · 29 currently recruiting

Active & Recent Trials

RECRUITING NA 2,425 participants

Project e-PBI+ - Parent Intervention to Reduce College Student Drinking and Cannabis Use

Penn State University

NCT05345951

RECRUITING 1,000 participants

Cannabis Use Registry to Improve Overall Understanding of Symptoms (CURIOUS)

HealthPartners Institute

NCT07227324

RECRUITING NA 500 participants

Effectiveness of Brief Intervention in Primary Care for Diverse Young People (Chat)

RAND

NCT06699251

RECRUITING NA 456 participants

Stress and Resilience

University of Washington

NCT06457841

RECRUITING Phase 2 350 participants

Cannabis' Impact on Alcohol Consumption

Brown University

NCT05389930

RECRUITING NA 280 participants

Neural and Psychiatric Consequences of Cannabis Use in Adolescents

University of Miami

NCT06941298

RECRUITING 242 participants

Impact of Cannabis Use During Third Molar Surgery

University of Michigan

NCT07423195

RECRUITING Phase 3 200 participants

Cannabis-Tobacco Co-Use Treatment Study

Medical University of South Carolina

NCT06883162

RECRUITING 200 participants

Study of Oral Fluid Testing Approach

Boston Children's Hospital

NCT06891235

RECRUITING NA 200 participants

Cannabis, Linked Emotions, and Adolescent Risk Study

Massachusetts General Hospital

NCT06576076

RECRUITING NA 180 participants

Cannabis Effects on Sleep, Circadian Rhythms, and Light Sensitivity in Young Adults

University of Pittsburgh

NCT06743373

RECRUITING NA 166 participants

Perceptual Influences From Smoking Cannabis: an Experimental Study

University of Colorado, Boulder

NCT06588582

RECRUITING Phase 1 140 participants

Maternal Choline Supplementation and Cannabis Use During Pregnancy: Impact on Early Brain Development

University of Colorado, Denver

NCT06379971

RECRUITING NA 136 participants

Mobile Intervention for Simultaneous Alcohol and Marijuana Use in Young Adults

Kaiser Permanente

NCT05991882

RECRUITING NA 120 participants

Feasibility/Acceptability of a Brief Motivational Intervention for Frequent/High-Intensity Cannabis Use

University of Washington

NCT07011615

RECRUITING NA 110 participants

Cannabis THC Potency, Metabolism, and Cognitive Impairment in Young Adults

University of California, San Francis

NCT06077292

RECRUITING Phase 1 100 participants

Effect of Cannabis on Cigarette Use Behavior

Johns Hopkins University

NCT06609083

RECRUITING Phase 1 100 participants

HIV and Alcohol Research Center Focused on Polypharmacy (HARP) Pilot 2 (2nd HARP Pilot Intervention)

Yale University

NCT06513819

RECRUITING NA 100 participants

Precision Brain Stimulation to Reduce Cannabis Craving in Schizophrenia

Vanderbilt University Medical Center

NCT07196462

RECRUITING Phase 1 100 participants

Effect of Cannabis on E-Cigarette Use Behavior

Johns Hopkins University

NCT06609109

RECRUITING NA 99 participants

Distinguishing Alcohol Intoxication, Cannabis Intoxication and Co-intoxication Using Electroencephalography (EEG)

Colorado State University

NCT06259916

RECRUITING NA 80 participants

Neuroimaging of Adolescent Cannabis Use Treatment

Indiana University

NCT07340554

RECRUITING Phase 1 80 participants

The Impact of Product Formulation on the Pharmacokinetics and Pharmacodynamics of Cannabis Edibles

Johns Hopkins University

NCT05602649

RECRUITING Phase 2 68 participants

Gabapentin for Restoring GABA/Glutamate Homeostasis in Co-occurring Bipolar and Cannabis Use Disorders

Medical University of South Carolina

NCT05064319

RECRUITING Phase 4 60 participants

Cannabis Use on Sedation for Oral Surgery Procedures

University of Oklahoma

NCT05873465

RECRUITING NA 52 participants

CARS: Cannabis and Alcohol Reduction Study

Medical University of South Carolina

NCT05486234

RECRUITING Phase 2 48 participants

Understanding the Clinical Pharmacology of Marijuana-Tobacco Co-administration

University of California, San Francis

NCT05999383

RECRUITING NA 30 participants

Characterization of Endocannabinoid and Endogenous Opioid Levels in Adolescents With Cannabis Use Disorder

University of Colorado, Denver

NCT05396638

RECRUITING Phase 1 24 participants

SV2A in Older Adults

Yale University

NCT05465538

ACTIVE NOT RECRUITING NA 60 participants

TECH App Marijuana Use Intervention for Court-Involved Adolescents

Northwestern University

NCT05979272

ACTIVE NOT RECRUITING Phase 2 40 participants

Cannabis Effects on Antiretroviral Therapy Pharmacokinetics and Neurotoxicity

University of California, San Diego

NCT04800159

ACTIVE NOT RECRUITING Early Phase 1 21 participants

Probing the Cannabinoid System in Individuals With a Family History of Psychosis

Yale University

NCT02102113

ACTIVE NOT RECRUITING Phase 4 12 participants

Effects of Pregnancy-associated Hormones on THC Metabolism in Women

University of Washington

NCT04374773

ACTIVE NOT RECRUITING NA 10 participants

Breathwork-assisted Treatment for Cannabis Use Disorder

Elias Dakwar

NCT05219825

COMPLETED NA 2,521 participants

Cannabis Edibles Packaging Descriptors Experiment

Wake Forest University Health Sciences

NCT06171399

COMPLETED NA 1,260 participants

Cannabis Edibles Packaging Imagery Experiment

Wake Forest University Health Sciences

NCT06358144

COMPLETED 151 participants

Cannabis Tolerance Break Resource Study: T-Break Guide

University of Vermont

NCT05382273

COMPLETED Phase 2 148 participants

Impact of Progesterone on Stress Reactivity and Cannabis Use

Medical University of South Carolina

NCT03729869

COMPLETED NA 146 participants

Alcohol and Cannabis Concentrates Co-Administration

University of Colorado, Denver

NCT05999344

COMPLETED 77 participants

Alcohol and Cannabis Co-Use and the Gut-Brain Axis

University of Colorado, Denver

NCT04998006

COMPLETED NA 60 participants

Impact of Reduced Cannabis Use on Functional Outcomes (R33 Phase)

Duke University

NCT04567238

COMPLETED NA 57 participants

Reducing Cannabis Use for Sleep Among Adults Using Medical Cannabis

University of Michigan

NCT03964974

COMPLETED NA 53 participants

CanCope: Digital Intervention for Coping With Cannabis Craving

Trustees of Dartmouth College

NCT05328362

COMPLETED NA 25 participants

Impact of Reduced Cannabis Use on Functional Outcomes

Duke University

NCT03681353

COMPLETED Phase 1 15 participants

Effect of Lorcaserin on Cannabis Withdrawal and Self-administration

New York State Psychiatric Institute

NCT03253926

Phase Distribution

PhaseTrial count
Early Phase 1 8
Phase 2 5
Phase 3 1
Phase 4 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Cannabis Use Trial Landscape

ClinicalTrials.gov lists 45 US studies indexed under Cannabis Use, and 29 of those are currently open to recruitment — roughly 64% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Cannabis Use shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 13 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Cannabis Use is led by Medical University of South Carolina with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 45 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Cannabis Use?

PlainTrial tracks 45 US clinical trials for Cannabis Use, of which 29 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Cannabis Use?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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