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Cannabis Use
Open-data reference.
45 US clinical trials · 29 currently recruiting
Active & Recent Trials
Project e-PBI+ - Parent Intervention to Reduce College Student Drinking and Cannabis Use
Penn State University
NCT05345951
Cannabis Use Registry to Improve Overall Understanding of Symptoms (CURIOUS)
HealthPartners Institute
NCT07227324
Effectiveness of Brief Intervention in Primary Care for Diverse Young People (Chat)
RAND
NCT06699251
Stress and Resilience
University of Washington
NCT06457841
Cannabis' Impact on Alcohol Consumption
Brown University
NCT05389930
Neural and Psychiatric Consequences of Cannabis Use in Adolescents
University of Miami
NCT06941298
Impact of Cannabis Use During Third Molar Surgery
University of Michigan
NCT07423195
Cannabis-Tobacco Co-Use Treatment Study
Medical University of South Carolina
NCT06883162
Study of Oral Fluid Testing Approach
Boston Children's Hospital
NCT06891235
Cannabis, Linked Emotions, and Adolescent Risk Study
Massachusetts General Hospital
NCT06576076
Cannabis Effects on Sleep, Circadian Rhythms, and Light Sensitivity in Young Adults
University of Pittsburgh
NCT06743373
Perceptual Influences From Smoking Cannabis: an Experimental Study
University of Colorado, Boulder
NCT06588582
Maternal Choline Supplementation and Cannabis Use During Pregnancy: Impact on Early Brain Development
University of Colorado, Denver
NCT06379971
Mobile Intervention for Simultaneous Alcohol and Marijuana Use in Young Adults
Kaiser Permanente
NCT05991882
Feasibility/Acceptability of a Brief Motivational Intervention for Frequent/High-Intensity Cannabis Use
University of Washington
NCT07011615
Cannabis THC Potency, Metabolism, and Cognitive Impairment in Young Adults
University of California, San Francis
NCT06077292
Effect of Cannabis on Cigarette Use Behavior
Johns Hopkins University
NCT06609083
HIV and Alcohol Research Center Focused on Polypharmacy (HARP) Pilot 2 (2nd HARP Pilot Intervention)
Yale University
NCT06513819
Precision Brain Stimulation to Reduce Cannabis Craving in Schizophrenia
Vanderbilt University Medical Center
NCT07196462
Effect of Cannabis on E-Cigarette Use Behavior
Johns Hopkins University
NCT06609109
Distinguishing Alcohol Intoxication, Cannabis Intoxication and Co-intoxication Using Electroencephalography (EEG)
Colorado State University
NCT06259916
Neuroimaging of Adolescent Cannabis Use Treatment
Indiana University
NCT07340554
The Impact of Product Formulation on the Pharmacokinetics and Pharmacodynamics of Cannabis Edibles
Johns Hopkins University
NCT05602649
Gabapentin for Restoring GABA/Glutamate Homeostasis in Co-occurring Bipolar and Cannabis Use Disorders
Medical University of South Carolina
NCT05064319
Cannabis Use on Sedation for Oral Surgery Procedures
University of Oklahoma
NCT05873465
CARS: Cannabis and Alcohol Reduction Study
Medical University of South Carolina
NCT05486234
Understanding the Clinical Pharmacology of Marijuana-Tobacco Co-administration
University of California, San Francis
NCT05999383
Characterization of Endocannabinoid and Endogenous Opioid Levels in Adolescents With Cannabis Use Disorder
University of Colorado, Denver
NCT05396638
SV2A in Older Adults
Yale University
NCT05465538
TECH App Marijuana Use Intervention for Court-Involved Adolescents
Northwestern University
NCT05979272
Cannabis Effects on Antiretroviral Therapy Pharmacokinetics and Neurotoxicity
University of California, San Diego
NCT04800159
Probing the Cannabinoid System in Individuals With a Family History of Psychosis
Yale University
NCT02102113
Effects of Pregnancy-associated Hormones on THC Metabolism in Women
University of Washington
NCT04374773
Breathwork-assisted Treatment for Cannabis Use Disorder
Elias Dakwar
NCT05219825
Cannabis Edibles Packaging Descriptors Experiment
Wake Forest University Health Sciences
NCT06171399
Cannabis Edibles Packaging Imagery Experiment
Wake Forest University Health Sciences
NCT06358144
Cannabis Tolerance Break Resource Study: T-Break Guide
University of Vermont
NCT05382273
Impact of Progesterone on Stress Reactivity and Cannabis Use
Medical University of South Carolina
NCT03729869
Alcohol and Cannabis Concentrates Co-Administration
University of Colorado, Denver
NCT05999344
Alcohol and Cannabis Co-Use and the Gut-Brain Axis
University of Colorado, Denver
NCT04998006
Impact of Reduced Cannabis Use on Functional Outcomes (R33 Phase)
Duke University
NCT04567238
Reducing Cannabis Use for Sleep Among Adults Using Medical Cannabis
University of Michigan
NCT03964974
CanCope: Digital Intervention for Coping With Cannabis Craving
Trustees of Dartmouth College
NCT05328362
Impact of Reduced Cannabis Use on Functional Outcomes
Duke University
NCT03681353
Effect of Lorcaserin on Cannabis Withdrawal and Self-administration
New York State Psychiatric Institute
NCT03253926
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 8 |
| Phase 2 | 5 |
| Phase 3 | 1 |
| Phase 4 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Cannabis Use Trial Landscape
ClinicalTrials.gov lists 45 US studies indexed under Cannabis Use, and 29 of those are currently open to recruitment — roughly 64% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Cannabis Use shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 13 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Cannabis Use is led by Medical University of South Carolina with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 45 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Cannabis Use?
PlainTrial tracks 45 US clinical trials for Cannabis Use, of which 29 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Cannabis Use?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.