Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Cannabis Use: early-phase trial registry
29 of 45 indexed Cannabis Use trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #323 of 28,707 conditions by registered trial count.
45 US clinical trials · 29 currently recruiting · #323 of 28,707 conditions by registered trial count
Cannabis Use: 45 US clinical trials tracked, 29 recruiting.
Cannabis Use is the subject of 45 registered US clinical trials on ClinicalTrials.gov, 29 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 13 in Phase 1-2 (earlier-stage). The most active sponsor is Medical University of South Carolina, running 4 of these trials.
Enrollment posture brief
Registry condition cannabis-use
OPEN 29 | RECR 64% | LATE 3 | EARLY 13 | RANK #323 | SPON 4
Volume-matched condition peers
Nearest open-share peer: Cardiac Rehabilitation (64% recruiting · 14 trials)
Cannabis Use lists 29 open slots (64% of 45 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Cannabis Use on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Cannabis Use is recruiting above its size-band peers.
29 of 45 indexed trials (64.4%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Cannabis Use trials is spread across many organizations.
Medical University of South Carolina accounts for 4 of 45 trials (8.9%). 29 distinct sponsors appear on at least one study for this condition label.
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Typical Cannabis Use enrolment sits around 100 participants.
Median target enrolment is 100 among the 45 trials that report a genuine target (sentinel values excluded). 20 of those (44.4%) plan for fewer than 100 participants.
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Cannabis Use research is mostly interventional.
40 interventional and 5 observational studies make up this index (88.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
45 total, page 1 of 1
Project e-PBI+ - Parent Intervention to Reduce College Student Drinking and Cannabis Use
Penn State University
NCT05345951
Cannabis Use Registry to Improve Overall Understanding of Symptoms (CURIOUS)
HealthPartners Institute
NCT07227324
Effectiveness of Brief Intervention in Primary Care for Diverse Young People (Chat)
RAND
NCT06699251
Stress and Resilience
University of Washington
NCT06457841
Cannabis' Impact on Alcohol Consumption
Brown University
NCT05389930
Neural and Psychiatric Consequences of Cannabis Use in Adolescents
University of Miami
NCT06941298
Impact of Cannabis Use During Third Molar Surgery
University of Michigan
NCT07423195
Cannabis-Tobacco Co-Use Treatment Study
Medical University of South Carolina
NCT06883162
Study of Oral Fluid Testing Approach
Boston Children's Hospital
NCT06891235
Cannabis, Linked Emotions, and Adolescent Risk Study
Massachusetts General Hospital
NCT06576076
Cannabis Effects on Sleep, Circadian Rhythms, and Light Sensitivity in Young Adults
University of Pittsburgh
NCT06743373
Perceptual Influences From Smoking Cannabis: an Experimental Study
University of Colorado, Boulder
NCT06588582
Maternal Choline Supplementation and Cannabis Use During Pregnancy: Impact on Early Brain Development
University of Colorado, Denver
NCT06379971
Mobile Intervention for Simultaneous Alcohol and Marijuana Use in Young Adults
Kaiser Permanente
NCT05991882
Feasibility/Acceptability of a Brief Motivational Intervention for Frequent/High-Intensity Cannabis Use
University of Washington
NCT07011615
Cannabis THC Potency, Metabolism, and Cognitive Impairment in Young Adults
University of California, San Francisco
NCT06077292
Effect of Cannabis on Cigarette Use Behavior
Johns Hopkins University
NCT06609083
HIV and Alcohol Research Center Focused on Polypharmacy (HARP) Pilot 2 (2nd HARP Pilot Intervention)
Yale University
NCT06513819
Precision Brain Stimulation to Reduce Cannabis Craving in Schizophrenia
Vanderbilt University Medical Center
NCT07196462
Effect of Cannabis on E-Cigarette Use Behavior
Johns Hopkins University
NCT06609109
Distinguishing Alcohol Intoxication, Cannabis Intoxication and Co-intoxication Using Electroencephalography (EEG)
Colorado State University
NCT06259916
Neuroimaging of Adolescent Cannabis Use Treatment
Indiana University
NCT07340554
The Impact of Product Formulation on the Pharmacokinetics and Pharmacodynamics of Cannabis Edibles
Johns Hopkins University
NCT05602649
Gabapentin for Restoring GABA/Glutamate Homeostasis in Co-occurring Bipolar and Cannabis Use Disorders
Medical University of South Carolina
NCT05064319
Cannabis Use on Sedation for Oral Surgery Procedures
University of Oklahoma
NCT05873465
CARS: Cannabis and Alcohol Reduction Study
Medical University of South Carolina
NCT05486234
Understanding the Clinical Pharmacology of Marijuana-Tobacco Co-administration
University of California, San Francisco
NCT05999383
Characterization of Endocannabinoid and Endogenous Opioid Levels in Adolescents With Cannabis Use Disorder
University of Colorado, Denver
NCT05396638
SV2A in Older Adults
Yale University
NCT05465538
TECH App Marijuana Use Intervention for Court-Involved Adolescents
Northwestern University
NCT05979272
Cannabis Effects on Antiretroviral Therapy Pharmacokinetics and Neurotoxicity
University of California, San Diego
NCT04800159
Probing the Cannabinoid System in Individuals With a Family History of Psychosis
Yale University
NCT02102113
Effects of Pregnancy-associated Hormones on THC Metabolism in Women
University of Washington
NCT04374773
Breathwork-assisted Treatment for Cannabis Use Disorder
Elias Dakwar
NCT05219825
Cannabis Edibles Packaging Descriptors Experiment
Wake Forest University Health Sciences
NCT06171399
Cannabis Edibles Packaging Imagery Experiment
Wake Forest University Health Sciences
NCT06358144
Cannabis Tolerance Break Resource Study: T-Break Guide
University of Vermont
NCT05382273
Impact of Progesterone on Stress Reactivity and Cannabis Use
Medical University of South Carolina
NCT03729869
Alcohol and Cannabis Concentrates Co-Administration
University of Colorado, Denver
NCT05999344
Alcohol and Cannabis Co-Use and the Gut-Brain Axis
University of Colorado, Denver
NCT04998006
Impact of Reduced Cannabis Use on Functional Outcomes (R33 Phase)
Duke University
NCT04567238
Reducing Cannabis Use for Sleep Among Adults Using Medical Cannabis
University of Michigan
NCT03964974
CanCope: Digital Intervention for Coping With Cannabis Craving
Trustees of Dartmouth College
NCT05328362
Impact of Reduced Cannabis Use on Functional Outcomes
Duke University
NCT03681353
Effect of Lorcaserin on Cannabis Withdrawal and Self-administration
New York State Psychiatric Institute
NCT03253926
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 8 |
| Phase 2 | 5 |
| Phase 3 | 1 |
| Phase 4 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Cannabis Use records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Cannabis Use trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Cannabis Use page
45 registered trials, 29 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 29 Cannabis Use trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Medical University of South Carolina sponsors the most Cannabis Use trials on record, review their full trial history before evaluating a specific study. See Medical University of South Carolina's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Cannabis Use condition card totals 45 registered trials; most-linked intervention Placebo; top US site state Colorado. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.