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Gastroparesis
Open-data reference.
45 US clinical trials · 24 currently recruiting
Active & Recent Trials
Indiana University Gastrointestinal Motility Diagnosis Registry
Indiana University
NCT04506593
Gastroparesis Outcome Longitudinal Database Enrolled Numerically
University of Louisville
NCT03876288
BSGM to Evaluate Patients With GI Symptoms
Children's Hospital of Philadelphia
NCT05880199
Prospective Evaluation of the Clinical Utility of Peroral Endoscopic Myotomy for Gastrointestinal Motility Disorders
AdventHealth
NCT05905016
IVIG for Drug and Device Refractory Gastrointestinal Auto-Immune Neuropathy
University of Louisville
NCT04208828
Different Doses of Naronapride Vs. Placebo in Gastroparesis
Dr. Falk Pharma
NCT05621811
GI Neuromuscular Pathology Prospective Registry
Indiana University
NCT02165059
Gastroparesis Registry 4
Johns Hopkins Bloomberg School of Public Health
NCT05846802
GpCRC Pediatric Gastroparesis Registry 2
Johns Hopkins Bloomberg School of Public Health
NCT05981300
Domperidone in Treating Patients With Gastrointestinal Disorders
M.D. Anderson Cancer Center
NCT01696734
Pyloric Sphincter Abnormalities in Patients With Gastroparesis Symptoms
Johns Hopkins Bloomberg School of Public Health
NCT04661215
Gastric Per-Oral Endoscopic Myotomy (G-POEM) for the Treatment of Gastroparesis
Indiana University
NCT04434781
Vagal Nerve Stimulation for Functional Dyspepsia and Gastroparesis
Massachusetts General Hospital
NCT03603730
Study of Enhanced Programming Stimulation with the Enterra® Therapy System
Enterra Medical
NCT06560307
Study of Enterra Programming with Nocturnal Cycling in Gastroparetics
Enterra Medical
NCT05980455
Impact of Per Oral Pyloromyotomy (POP) on Glycemic Control in Diabetes
Matthew Allemang
NCT04696159
Transpyloric Stenting As a Predictor for G-POEM for Refractory Gastroparesis
Northwestern University
NCT04287647
Study of Gastric Motility in Eosinophilic Gastritis
Children's Hospital Medical Center, Cincinnati
NCT05229432
Central and Peripheral Effects of Cognitive Behavioral Therapy on Brain-Gut Axis Signaling in Gastroparetic Patients
Massachusetts General Hospital
NCT03531450
The Use of Body Surface Gastric Mapping in Assessing the Clinical Success of G-POEM
Indiana University
NCT06493032
Compassionate Use of Domperidone for Refractory Gastroparesis
Children's Mercy Hospital Kansas City
NCT04699591
TENS in Scleroderma
University of Michigan
NCT06646913
Brain-Gut Yoga for Functional Dyspepsia and Gastroparesis (FD-GP)
Wake Forest University Health Sciences
NCT06732453
Growth Hormone for the Treatment of Gastroparesis
Mayo Clinic
NCT06803589
Cardiac Vagal Effects of GES in Patients With Gastroparesis and Vagal Nerve Action Potentials in Vagus Nerve
Indiana University
NCT02159586
Prospective Evaluation of the Efficacy and Safety of Submucosal Endoscopy
University of Colorado, Denver
NCT03626350
ABVN Phase 2-Studying the Effect of Stimulation on the Auricular Branch of the Vagal Nerve
Indiana University
NCT06491758
Endoscopic Myotomy of the Pylorus To Improve Emptying and Symptoms Trial
Matthew Allemang
NCT05039424
Vagus Nerve Response in Gastroparesis Patients
Indiana University
NCT04207996
Magnetic Resonance Imaging of the Brain and Stomach in Healthy Volunteers and Gastroparesis
Indiana University School of Medicine
NCT04282317
Magnetically Controlled Capsule Endoscopy Feasibility Study in Gastric Motility
University of California, Los Angeles
NCT05004012
Establishing a Pediatric Reference Range for the 13C-Spirulina Gastric Emptying Breath Test (GEBT)
Cairn Diagnostics
NCT06004596
Study to Assess the Efficacy of VLY-686 in Relieving Symptoms of Gastroparesis
Vanda Pharmaceuticals
NCT02970968
A Comparison of SmartPill Capsule With Scintigraphy for Determining Gastric Residence Time
The SmartPill Corporation
NCT00128284
Using Point-of-Care-Ultrasound (POCUS) to Assess Gastric Contents Among Fasting Pre-operative Patients Taking GLP-1 Agonists.
University of North Carolina, Chapel Hill
NCT06038734
Dose Response of 28 Days of Dosing of GSK962040 in Type I and II Diabetic Male and Female Subjects With Gastroparesis
GlaxoSmithKline
NCT01262898
Holding vs. Continuing Incretin-based Therapies Before Upper Endoscopy
The Cleveland Clinic
NCT06533527
Modulation of Heme Oxygenase 1 by Nizatidine and Lisinopril in Healthy Subjects
Adil Bharucha
NCT02232308
Transcutaneous Electroacupuncture for Gastric Complications of Scleroderma
Johns Hopkins University
NCT03294616
Study to Assess Pharmacodynamics of RM-131 in Patients With Diabetic Gastroparesis
Motus Therapeutics
NCT01394055
Sancuso® for Gastroparesis: An Open Label Study.
Temple University
NCT01989221
Pioglitazone for Idiopathic Gastroparesis
Johns Hopkins University
NCT04300127
Validation of Plant-Based Vegan Meal for Gastric Emptying Testing in 10 Healthy Subjects
Mayo Clinic
NCT06991036
Safety and Pharmacokinetic Study of C13-URA in Healthy Volunteers
Otsuka Pharmaceutical Co.
NCT01074710
Endoscopic Full Thickness Biopsy, Gastric Wall.
Mayo Clinic
NCT01650714
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 6 |
| Phase 2 | 3 |
| Phase 3 | 2 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Gastroparesis Trial Landscape
ClinicalTrials.gov lists 45 US studies indexed under Gastroparesis, and 24 of those are currently open to recruitment — roughly 53% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Gastroparesis shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 9 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Gastroparesis is led by Indiana University with 7 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 45 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Gastroparesis?
PlainTrial tracks 45 US clinical trials for Gastroparesis, of which 24 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Gastroparesis?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.