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NCT06609109 · ClinicalTrials.gov registry record · Phase 1
Effect of Cannabis on E-Cigarette Use Behavior
A Phase 1 study of Tobacco Use and Cannabis Use, sponsored by Johns Hopkins University.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 100
- Enrollment target
- 1
- Study location
NCT06609109: Recruiting Phase 1 study of Tobacco Use and Cannabis Use, sponsored by Johns Hopkins University.
NCT06609109 is a Phase 1 study of Tobacco Use and Cannabis Use that is actively recruiting participants, run by Johns Hopkins University. The registered enrollment target is 100 participants, below the 378-participant average among 76 other Tobacco Use trials with a reported enrollment target (74% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06609109, a Phase 1 study of Tobacco Use and Cannabis Use, is actively recruiting participants, sponsored by Johns Hopkins University.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to determine the impact of tetrahydrocannabinol (THC) administration on motivational, subjective, and physiological effects of electronic cigarettes. The study's goals are to test demand for e-cigarettes, tobacco craving, affect, heart rate, blood pressure, expired breath carbon monoxide, and cognitive performance. Researchers will compare multiple doses of THC and a placebo in participants who smoke e-cigarettes and either smoke or vape THC in the laboratory.
Primary Outcome
Consumption of e-cigarette puffs at unconstrained price as measured by an incentivized demand task. Minimum value is 0, maximum value is not constrained. Higher scores indicate more consumption at unconstrained price (a worse outcome).
Conditions Studied
Interventions
- DRUG THC 0mg
- DRUG THC High Dose
- DRUG THC Low Dose
- DRUG E-Cigarette Full Nicotine
- DRUG E-Cigarette Placebo Nicotine
Study Locations (1)
Maryland
- Johns Hopkins University Behavioral Pharmacology Research Unit - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2025-03-19 |
| Est. Completion | 2029-10-01 |
| Phase | Phase 1 |
What NCT06609109 shows while recruiting
NCT06609109 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 378-participant average among 76 other Tobacco Use trials with a reported enrollment target (74% lower).
The record links to 3 conditions, with Tobacco Use appearing as the primary indexed condition, and to 5 interventions - of which THC 0mg is the first listed.
NCT06609109 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT06609109 about?
NCT06609109 is a clinical study titled "Effect of Cannabis on E-Cigarette Use Behavior". The purpose of this study is to determine the impact of tetrahydrocannabinol (THC) administration on motivational, subjective, and physiological effects of electronic cigarettes. The study's goals are to test demand for e-cigarettes, tobacco craving, affect, heart rate, blood pressure, expired breat...
What is the current status of trial NCT06609109?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 100 participants. The study started on 2025-03-19. Estimated completion is 2029-10-01.
What conditions does trial NCT06609109 study?
This clinical trial studies the following conditions: Tobacco Use, Cannabis Use, Electronic Cigarette Use.
What interventions are being tested in trial NCT06609109?
The interventions under investigation include: THC 0mg (DRUG), THC High Dose (DRUG), THC Low Dose (DRUG), E-Cigarette Full Nicotine (DRUG), E-Cigarette Placebo Nicotine (DRUG).
Who is sponsoring clinical trial NCT06609109?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06609109 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Tobacco Use
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06609109's enrollment target sits among peer trials
100 39th of 76 higher than 36 of 76 other Tobacco Use trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Tobacco Use trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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