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NCT03729869 · ClinicalTrials.gov registry record · Phase 2
Impact of Progesterone on Stress Reactivity and Cannabis Use
A Phase 2 study of Cannabis Use, sponsored by Medical University of South Carolina.
- Completed
- Registry status
- Phase 2
- Development phase
- 148
- Enrollment target
- 1
- Study location
NCT03729869: Completed Phase 2 study of Cannabis Use, sponsored by Medical University of South Carolina.
NCT03729869 is a Phase 2 study of Cannabis Use that has completed, run by Medical University of South Carolina. The registered enrollment target is 148 participants, below the 276-participant average among 44 other Cannabis Use trials with a reported enrollment target (46% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03729869, a Phase 2 study of Cannabis Use, has completed, sponsored by Medical University of South Carolina.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 148 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a research study to find out if a hormone called progesterone affects marijuana users' stress response and marijuana use. Progesterone is a naturally occurring sex hormone involved in the menstrual cycle and reproduction, and has been shown to reduce withdrawal symptoms when people stop using substances like cocaine and nicotine. It is not FDA approved for treating cannabis users and is considered an investigational drug in this study.
Primary Outcome
Subjects will rate marijuana craving on a 0-7 Likert scale where 0 is Not at All and 7 is extremely.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Progesterone
Study Locations (1)
South Carolina
- Medical University of South Carolina - Charleston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 148 participants |
| Start Date | 2019-01-18 |
| Est. Completion | 2022-11-09 |
| Phase | Phase 2 |
What the finished NCT03729869 record still lists
NCT03729869 is an interventional study that assigns participants to a tested intervention. The registered 148 participants enrollment target is mid-sized for trials with a published cap, below the 276-participant average among 44 other Cannabis Use trials with a reported enrollment target (46% lower).
The record links to 1 condition, with Cannabis Use appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT03729869 reports a single indexed study location in South Carolina.
Frequently Asked Questions
What is clinical trial NCT03729869 about?
NCT03729869 is a clinical study titled "Impact of Progesterone on Stress Reactivity and Cannabis Use". This is a research study to find out if a hormone called progesterone affects marijuana users' stress response and marijuana use. Progesterone is a naturally occurring sex hormone involved in the menstrual cycle and reproduction, and has been shown to reduce withdrawal symptoms when people stop usin...
What is the current status of trial NCT03729869?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 148 participants. The study started on 2019-01-18. Estimated completion is 2022-11-09.
What conditions does trial NCT03729869 study?
This clinical trial studies the following conditions: Cannabis Use.
What interventions are being tested in trial NCT03729869?
The interventions under investigation include: Placebo (DRUG), Progesterone (DRUG).
Who is sponsoring clinical trial NCT03729869?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03729869 being conducted?
This trial has 1 study location across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cannabis Use
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03729869's enrollment target sits among peer trials
148 16th of 44 higher than 29 of 44 other Cannabis Use trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cannabis Use trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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