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NCT04800159 · ClinicalTrials.gov registry record · Phase 2
Cannabis Effects on Antiretroviral Therapy Pharmacokinetics and Neurotoxicity
A Phase 2 study of HIV and Cannabis Use, sponsored by University of California, San Diego.
- Active
- Registry status
- Phase 2
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT04800159: Active Phase 2 study of HIV and Cannabis Use, sponsored by University of California, San Diego.
NCT04800159 is a Phase 2 study of HIV and Cannabis Use that is active but no longer recruiting, run by University of California, San Diego. The registered enrollment target is 40 participants, below the 440-participant average among 303 other HIV trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04800159, a Phase 2 study of HIV and Cannabis Use, is active but no longer recruiting, sponsored by University of California, San Diego.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will address whether cannabis affects antiretroviral therapy (ART) drug concentrations, mood, and thinking. The project will have two phases. Phase 1 is an observational study, in which 120 people will be assessed to evaluate the effects of chronic cannabis use on ART drug concentrations, mood, and thinking. In Phase 2, the study will administer cannabis (or placebo) to 40 people to examine its acute effects on ART drug concentrations.
Primary Outcome
This will be done separately for participants who use ART drugs that are predominantly metabolized by cytochrome P450 (CYP) or uridine 5'-diphospho-glucuronosyltransferase (UGT) (estimated N=60 in each).
Conditions Studied
Interventions
- DRUG Placebo
- DRUG THC Cannabis
- DRUG CBD Cannabis
Study Locations (1)
California
- Ucsd Hnrp-Cmcr - San Diego
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2021-02-19 |
| Est. Completion | 2026-04-30 |
| Phase | Phase 2 |
What the registry record for NCT04800159 still lists
NCT04800159 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 440-participant average among 303 other HIV trials with a reported enrollment target (91% lower).
The record links to 2 conditions, with HIV appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.
NCT04800159 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT04800159 about?
NCT04800159 is a clinical study titled "Cannabis Effects on Antiretroviral Therapy Pharmacokinetics and Neurotoxicity". This study will address whether cannabis affects antiretroviral therapy (ART) drug concentrations, mood, and thinking. The project will have two phases. Phase 1 is an observational study, in which 120 people will be assessed to evaluate the effects of chronic cannabis use on ART drug concentrations,...
What is the current status of trial NCT04800159?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 2021-02-19. Estimated completion is 2026-04-30.
What conditions does trial NCT04800159 study?
This clinical trial studies the following conditions: HIV, Cannabis Use.
What interventions are being tested in trial NCT04800159?
The interventions under investigation include: Placebo (DRUG), THC Cannabis (DRUG), CBD Cannabis (DRUG).
Who is sponsoring clinical trial NCT04800159?
This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04800159 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for HIV
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04800159's enrollment target sits among peer trials
40 243rd of 303 higher than 58 of 303 other HIV trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other HIV trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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