Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Cognitive Change: early-phase trial registry
25 of 45 indexed Cognitive Change trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #323 of 28,707 conditions by registered trial count.
45 US clinical trials · 25 currently recruiting · #323 of 28,707 conditions by registered trial count
Cognitive Change: 45 US clinical trials tracked, 25 recruiting.
Cognitive Change is the subject of 45 registered US clinical trials on ClinicalTrials.gov, 25 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is University of Illinois at Urbana-Champaign, running 3 of these trials.
Enrollment posture brief
Registry condition cognitive-change
OPEN 25 | RECR 56% | LATE 1 | EARLY 6 | RANK #323 | SPON 3
Volume-matched condition peers
Nearest open-share peer: Acute Lymphoblastic Leukemia, Pediatric (56% recruiting · 9 trials)
Cognitive Change lists 25 open slots (56% of 45 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Cognitive Change on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Cognitive Change is recruiting above its size-band peers.
25 of 45 indexed trials (55.6%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Cognitive Change trials is spread across many organizations.
University of Illinois at Urbana-Champaign accounts for 3 of 45 trials (6.7%). 36 distinct sponsors appear on at least one study for this condition label.
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Most Cognitive Change trials plan to enrol fewer than 100 people.
Median target enrolment is 75 among the 45 trials that report a genuine target (sentinel values excluded). 30 of those (66.7%) plan for fewer than 100 participants.
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Cognitive Change research is mostly interventional.
40 interventional and 5 observational studies make up this index (88.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
45 total, page 1 of 1
Effectiveness of Cognitive Training in Older and Younger Adults
University of Wisconsin, Madison
NCT06375681
Moderators and Mediators of Perceptual Learning
University of Wisconsin, Madison
NCT05894967
Executive Function Training for Children and Adolescents
Northeastern University
NCT07147894
Enhancing Children's Cognitive Function and Achievement Through Carotenoid Consumption
University of Illinois at Urbana-Champaign
NCT05177679
Exercise to Improve Brain Health in Older African Americans
Rutgers, The State University of New Jersey
NCT05597124
HomeStyles-2: Shaping HOME Environments and LifeSTYLES to Prevent Childhood Obesity
Rutgers, The State University of New Jersey
NCT04802291
Building a Platform for Precision Anesthesia in the Geriatric Surgical Patient
Stanford University
NCT03839784
Brain Health Virtual Reality Study
University of California, San Diego
NCT06124339
Cognition After OSA Treatment Among Native American People (CATNAP)
Washington State University
NCT06227572
Time-in-bed Restriction in Older Adults With Sleep Difficulties With and Without Risk for Alzheimer's Disease
University of Pittsburgh
NCT05138848
Trout Consumption in Young Children and Families and Brain Health
University of Idaho
NCT06721468
Memantine and Exercise to Improve Cognitive Function and Modulate Biological Pathways of Cognitive Decline During Chemotherapy in Breast Cancer
UNC Lineberger Comprehensive Cancer Center
NCT06727773
The Role of the Time of Day in the Effects of Exercise on Memory in Heathy Young Adults
University of North Carolina, Greensboro
NCT04861818
Working Memory Training for People Aging with HIV
Northeastern University
NCT06699927
Optimized Tailored Interventions in Metabolic and Lifestyle Outcomes (OPTIMAL)
University of Illinois at Urbana-Champaign
NCT06605898
Modulating Neurocognitive Processes of Learning to Trust and Distrust in Aging
University of Florida
NCT05457725
Resilience to Sleep Deprivation and Changes in Sleep Architecture in Shoonya Meditators
Beth Israel Deaconess Medical Center
NCT05026541
Cognitive Impairment in Colorectal Cancer Patients Receiving Cytotoxic Chemotherapy
Joseph McCollom
NCT05014399
Amplitude Titration to Improve ECT Clinical Outcomes
University of New Mexi
NCT05699226
Cognitive Augmentation Via Multimodal Sensing and Auricular Neurostimulation
OpenBCI
NCT06782360
Remote Evaluation of MIND Diet
University of Illinois at Urbana-Champaign
NCT06450977
Surviving Daily Life
Thomas Jefferson University
NCT07054723
Improving Cognitive Function Through High-intensity Interval Training in Breast Cancer Patients Undergoing Chemotherapy
Dana-Farber Cancer Institute
NCT04724499
Using Non-invasive Brain Stimulation to Treat Word Finding Difficulty in Chronic Traumatic Brain Injury
Beth Israel Deaconess Medical Center
NCT06848140
Cognitive Impact of Neoadjuvant Chemotherapy for Ovarian Cancer
University of Wisconsin, Madison
NCT07125209
Acute Cognitive Changes During Atrial Fibrillation Episodes (AFCOG)
David Brunk, PA-C, MMS
NCT04033510
PhytoSERM to Prevent Menopause Associated Decline in Brain Metabolism and Cognition
Roberta Brinton
NCT05664477
Osteopathic Manipulation Makes a Neuropsychological Difference
Midwestern University
NCT04058431
WHNRC (Western Human Nutrition Research Center) Honey Study
USDA, Western Human Nutrition Research Center
NCT06107231
Predictors of Cognitive Outcomes in Geriatric Depression
David Steffens
NCT05273996
Altering Multitasking Behavior Using Low Current Brain Stimulation
Tufts University
NCT03873636
Mindfulness Training in Special Operations Forces (SOF) Candidates
University of Miami
NCT04703296
Dietary Exchanges With Avocado and Mango in Pre-diabetes
Clinical Nutrition Research Center, Illinois Institute of Technology
NCT05353790
Nutrition, Vision, and Cognition in Sport Study: Beef
Texas A&M University
NCT04427852
Neural Mechanisms of Mindfulness
Washington University School of Medicine
NCT03466164
The VRIF Trial: Hypoglycemia Reduction With Automated-Insulin Delivery System
University of Virginia
NCT03674281
Computerized Cognitive Training in Breast Cancer Survivors
Ohio State University
NCT05570604
Brain Exercises for Synaptic Plasticity
University of Kentucky
NCT03058055
Measuring Mindfulness Application
University of Miami
NCT04589195
Acute Effects of Naturally Occurring Tea and Coffee-based Ingredients on Cognitive Performance
The Center for Applied Health Sciences
NCT06062186
Effect of PeakATP on Mood, Reaction Time and Cognition
University of Central Florida
NCT05100589
Yoga Training and Retinal Vasculature
University of Miami
NCT06099405
Aquatic Exercise for Cognition and Mobility in Older Adults
Emily Dunlap
NCT05501249
Treatment of Spinal Cord Injury Patients for Neurogenic Bladder: Anticholinergic Agent vs. Mirabegron
The University of Texas Health Science Center at San Antonio
NCT03612401
Treating Civilian Traumatic Brain Injury With High Definition Transcranial Direct Current Stimulation (ciTBI-HDtDCS)
The University of Texas at Dallas
NCT05408975
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 3 |
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Cognitive Change records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Cognitive Change trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Cognitive Change page
45 registered trials, 25 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 25 Cognitive Change trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of Illinois at Urbana-Champaign sponsors the most Cognitive Change trials on record, review their full trial history before evaluating a specific study. See University of Illinois at Urbana-Champaign's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Cognitive Change condition card totals 45 registered trials; most-linked intervention Sham Transcranial direct current stimulation; top US site state Massachusetts. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.