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NCT04567238 · ClinicalTrials.gov registry record · NA
Impact of Reduced Cannabis Use on Functional Outcomes (R33 Phase)
A NA study of Cannabis Use and Cannabis, sponsored by Duke University.
- Completed
- Registry status
- NA
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT04567238: Completed NA study of Cannabis Use and Cannabis, sponsored by Duke University.
NCT04567238 is a NA study of Cannabis Use and Cannabis that has completed, run by Duke University. The registered enrollment target is 60 participants, below the 278-participant average among 44 other Cannabis Use trials with a reported enrollment target (78% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04567238, a NA study of Cannabis Use and Cannabis, has completed, sponsored by Duke University.
- COMPLETED
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
Nearly 20 million Americans report use of cannabis in the past month, and heavy cannabis use has increased by nearly 60% in the U.S. since 2007. Heavy cannabis use is associated with lower educational attainment, reduced physical activity, increased rates of addiction and unemployment, and neuropsychological deficits. Studies suggest that cannabis use is also associated with increased mental health symptoms, drugged driving, and traffic accidents. While there is evidence that sustained abstinence can lead to improvements in the functional outcomes of former users, the degree to which reductions alone (i.e., not sustained abstinence) in cannabis use might be associated with positive changes in functional outcomes is unknown. This is a critical gap in the literature, as many interventions for cannabis and other drugs are associated with decreases in frequency and quantity of use, but fail to achieve an effect on overall abstinence rates. The objective of the present research is to use ecological momentary assessment (EMA), a real-time, naturalistic data collection method, to prospectively study the impact of reduced cannabis use on functional outcomes in heavy cannabis users. Contingency management (CM) will be used to promote reductions in frequency and quantity of cannabis use. CM is an intensive behavioral therapy that is highly effective at producing short-term reductions in illicit drug use. We have recently developed a novel approach that leverages mobile technology and recent developments in cannabis testing. We have pilot-tested this approach with heavy cannabis users and found that it is an acceptable and feasible method. The present research will use this technology in conjunction with EMA methods to study the impact of reduced cannabis use on key functional outcomes. Our central hypothesis is that reductions in frequency and quantity of cannabis use will lead to positive changes in cannabis users' mental health, self-efficacy, physical activity, working mem
Primary Outcome
Mental health symptoms will be measured by the 90-item Symptom Checklist (SCL-90). This measure has a scoring range of 0 to 360, with lower scores indicating lower distress related to mental health.
Conditions Studied
Interventions
- BEHAVIORAL Mobile contingency management
Study Locations (1)
North Carolina
- Duke University Medical Center - Durham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2021-03-19 |
| Est. Completion | 2023-11-22 |
| Phase | NA |
What the finished NCT04567238 record still lists
NCT04567238 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 278-participant average among 44 other Cannabis Use trials with a reported enrollment target (78% lower).
The record links to 2 conditions, with Cannabis Use appearing as the primary indexed condition, and to 1 intervention - of which Mobile contingency management is the first listed.
NCT04567238 reports a single indexed study location in North Carolina.
Frequently Asked Questions
What is clinical trial NCT04567238 about?
NCT04567238 is a clinical study titled "Impact of Reduced Cannabis Use on Functional Outcomes (R33 Phase)". Nearly 20 million Americans report use of cannabis in the past month, and heavy cannabis use has increased by nearly 60% in the U.S. since 2007. Heavy cannabis use is associated with lower educational attainment, reduced physical activity, increased rates of addiction and unemployment, and neuropsyc...
What is the current status of trial NCT04567238?
This trial is currently completed. It is a NA study. The enrollment target is 60 participants. The study started on 2021-03-19. Estimated completion is 2023-11-22.
What conditions does trial NCT04567238 study?
This clinical trial studies the following conditions: Cannabis Use, Cannabis.
What interventions are being tested in trial NCT04567238?
The interventions under investigation include: Mobile contingency management (BEHAVIORAL).
Who is sponsoring clinical trial NCT04567238?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04567238 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cannabis Use
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04567238's enrollment target sits among peer trials
60 31st of 44 higher than 12 of 44 other Cannabis Use trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cannabis Use trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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