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NCT04567238 · ClinicalTrials.gov registry record · NA

Impact of Reduced Cannabis Use on Functional Outcomes (R33 Phase)

A NA study of Cannabis Use and Cannabis, sponsored by Duke University.

Completed
Registry status
NA
Development phase
60
Enrollment target
1
Study location

NCT04567238 is a NA study of Cannabis Use and Cannabis that has completed, run by Duke University. The registered enrollment target is 60 participants, below the 278-participant average among 44 other Cannabis Use trials with a reported enrollment target (78% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT04567238, a NA study of Cannabis Use and Cannabis, has completed, sponsored by Duke University.

COMPLETED
Registry status
NA
Development phase
60 participants
Enrollment target
1
Study location

Study Summary

Nearly 20 million Americans report use of cannabis in the past month, and heavy cannabis use has increased by nearly 60% in the U.S. since 2007. Heavy cannabis use is associated with lower educational attainment, reduced physical activity, increased rates of addiction and unemployment, and neuropsychological deficits. Studies suggest that cannabis use is also associated with increased mental health symptoms, drugged driving, and traffic accidents. While there is evidence that sustained abstinence can lead to improvements in the functional outcomes of former users, the degree to which reductions alone (i.e., not sustained abstinence) in cannabis use might be associated with positive changes in functional outcomes is unknown. This is a critical gap in the literature, as many interventions for cannabis and other drugs are associated with decreases in frequency and quantity of use, but fail to achieve an effect on overall abstinence rates. The objective of the present research is to use ecological momentary assessment (EMA), a real-time, naturalistic data collection method, to prospectively study the impact of reduced cannabis use on functional outcomes in heavy cannabis users. Contingency management (CM) will be used to promote reductions in frequency and quantity of cannabis use. CM is an intensive behavioral therapy that is highly effective at producing short-term reductions in illicit drug use. We have recently developed a novel approach that leverages mobile technology and recent developments in cannabis testing. We have pilot-tested this approach with heavy cannabis users and found that it is an acceptable and feasible method. The present research will use this technology in conjunction with EMA methods to study the impact of reduced cannabis use on key functional outcomes. Our central hypothesis is that reductions in frequency and quantity of cannabis use will lead to positive changes in cannabis users' mental health, self-efficacy, physical activity, working mem

Conditions Studied

Interventions

  • BEHAVIORAL Mobile contingency management

Study Locations (1)

North Carolina

  • Duke University Medical Center - Durham

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2021-03-19
Est. Completion 2023-11-22
Phase NA

Sponsor

Duke University

1,725 total trials

What the Registry Record Tells You About NCT04567238

The ClinicalTrials.gov registry entry for NCT04567238 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 278-participant average among 44 other Cannabis Use trials with a reported enrollment target (78% lower). The listed sponsor is Duke University, which has 1,725 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Cannabis Use appearing as the primary indexed condition, and to 1 intervention - of which Mobile contingency management is the first listed.

NCT04567238 reports 1 study location spanning 1 distinct geographic area - top geographies include North Carolina.

Frequently Asked Questions

What is clinical trial NCT04567238 about?

NCT04567238 is a clinical study titled "Impact of Reduced Cannabis Use on Functional Outcomes (R33 Phase)". Nearly 20 million Americans report use of cannabis in the past month, and heavy cannabis use has increased by nearly 60% in the U.S. since 2007. Heavy cannabis use is associated with lower educational attainment, reduced physical activity, increased rates of addiction and unemployment, and neuropsyc...

What is the current status of trial NCT04567238?

This trial is currently completed. It is a NA study. The enrollment target is 60 participants. The study started on 2021-03-19. Estimated completion is 2023-11-22.

What conditions does trial NCT04567238 study?

This clinical trial studies the following conditions: Cannabis Use, Cannabis.

What interventions are being tested in trial NCT04567238?

The interventions under investigation include: Mobile contingency management (BEHAVIORAL).

Who is sponsoring clinical trial NCT04567238?

This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04567238 being conducted?

This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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