Wake Forest University Health Sciences
Trial Pipeline
Role of Mitochondrial Bioenergetics in Resilience for Gynecologic Cancer
NCT07046936
Metformin Hydrochloride in Combination With Standard of Care Systemic Therapy in Previously Untreated Advanced Unresectable or Metastatic Soft Tissue Sarcoma
NCT07291297
Intra-abdominal Pressure (IAP) During PFA Treatment of A-fib/ A-Flutter
NCT06876896
Safety and Feasibility Study of Autologous Engineered Urethral Constructs for the Treatment of Strictures
NCT03258658
Pre-malignant States to Hematologic Malignancies in Firefighters
NCT06870760
A Novel Dialectical Behavior Therapy Brief Group Intervention for Cigarette Smoking by Patients With Cancer: An Open Clinical Trial
NCT07119489
Assessing and Addressing Health-Related Social Needs Among Families of Children With Cancer
NCT07278414
Optimizing Self-Monitoring Feedback Delivery for the Treatment of Overweight and Obesity
NCT07227051
ONC-MM-2407: The Effect of Virtual Reality Headsets on Pain and Anxiety in the Peri and Post Bone Marrow Biopsy Period
NCT07203534
Vital Coach: A Study of Resiliency in Medical Students
NCT07342673
Surgical Thromboprophylaxis Practices in Oncology Patients Within the NCORP Network, STOP-VTE Study
NCT07215624
Evaluation of Flexible Conductive Hearing Aids
NCT07222202
Effectiveness of Magnesium in Addition to Prochlorperazine for the Treatment of Migraines
NCT06904287
Pilot Study of Fisetin to Improve Fatigue Among Older Adult Cancer Survivors
NCT06819254
R.E.C.K vs Exparel in Robotic Nephrectomy
NCT07092566
Deprescribing in Outpatient Internal Medicine Practices
NCT07226960
Inhaled Nitric Oxide in Acute Ischemic Stroke Patients Undergoing Mechanical Thrombectomy
NCT05871606
Comparison of Urinary Flow Study
NCT06918067
Intranasal and Intravenous Oxytocin for Analgesia to Noxious Heat Pain
NCT07053774
Oral Gastric Suctioning Effect on Transesophageal Echo
NCT07209293
A Skin Image Reference Tool to Aid Healthcare Providers' Diagnosis
NCT07033169
Bracing and Reconstruction of the Anterior Cruciate Ligament for Efficacy Trial
NCT06942754
Education & Mentorship of Advanced Practice Providers to Increase Community-based Research Within the NCORP Network, COACH-APP Trial
NCT06904391
Bump the Lump - Intervention for the Treatment of Globus Pharyngeus
NCT06762444
A Single-arm, Phase II Clinical Trial of ASPIRin to prEvent Venous Thromboembolism in Patients With Advanced Germ Cell Tumors Receiving Chemotherapy
NCT06866964
Validation of Chronic Obstructive Pulmonary Disease (COPD) Algorithm
NCT07223749
LCI-SAR-BSTS-CTDNA-001: Circulating Tumor DNA Liquid Biopsy in Sarcoma Patients
NCT06958107
Sequential Multiple Assignment Randomized Trial to Reduce Food Insecurity
NCT07031739
Quitting Matters Human Immunodeficiency Virus Hybrid Trial
NCT06883097
Standardized Application of Feeding Evaluations Using SMART Tool
NCT07136610
Enhancing Physical Function in Older Adults With Chronic Kidney Disease
NCT06738394
The Better, Harder, Faster, Stronger Study
NCT07220512
Evaluating Microarray Pharmacogenetic Testing in Cancer Patients
NCT06489041
Nurturing Outreach for Understanding and Reducing Inpatient Security of Health
NCT07010289
ONC-LEUK-2406: The Impact of Systematic Financial Navigation in Acute Myeloid Leukemia
NCT06945042
Identifying and Treating Depression in the Orthopaedic Trauma Population
NCT05976347
Emergency Medical Services (EMS) Telehealth to Speed STEMI Reperfusion
NCT06945900
Brain-Gut Yoga for Functional Dyspepsia and Gastroparesis (FD-GP)
NCT06732453
Feasibility of an ADAPTive Intervention to Improve Food Security and Maternal-Child Health
NCT06942598
Comparison of Single vs. Dual Perclose Devices for Large-Bore Access Closure in TAVR
NCT06871774
Development of Quantitative Muscle Imaging as a Biomarker of Disease Endpoints in Myotonic Dystrophy
NCT07362875
COmmunities Aligned to Reduce Concussion and Head Impact Exposure
NCT06624202
M-PART in Head and Neck Cancer Patients Treated With KeraStat Cream for Acute Radiation Dermatitis
NCT06441266
Evaluating the Effect of Surgical Drain Securement on Patient Quality of Life and Postoperative Drain-related Complications
NCT06916286
Project neuroARTEMIS
NCT06814275
Seizure Prevention in Traumatic Brain Injury With Levetiracetam and Lacosamide
NCT06866691
Toxicity Genetic Determinants and Response to Azacitidine and Venetoclax in AML
NCT06580106
Cancer-related Fatigue During Maintenance Immunotherapy for Non-small Cell Lung Cancer (NSCLC): a Qualitative Study
NCT06567704
Transcranial Magnetic Stimulation (TMS) Effects Using Magnetoencephalography (MEG) Study
NCT06770556
Patient Descriptors Of Cancer-Related Fatigue: A Mixed Methods Pilot Study Of Cancer Survivors
NCT06634381
CHAAMP (CHArlotte Advocate MGUS Project) Internal Pilot Study
NCT06644625
Nivolumab in Multiple Myeloma Patients After Idecabtagene Vicleucel
NCT06523621
COPD Care Pathway Among Patients With Cancer
NCT05984680
Discharge Medication Use Post-Operatively in GU Cancer Patients
NCT06795087
Efficacy of 3D-Printed Mouth Splints
NCT06801535
Safety and Efficacy of Aloe Vera in the Management of the Symptoms of Interstitial Cystitis
NCT04734106
Telehealth Intervention for Improving Distress and Financial Toxicity in the Caregivers
NCT06709404
Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
NCT06418204
Evaluation of the Pathobiology of CALR-mutated MPN Cells
NCT06480591
Postoperative Radiotherapy for Intermediate- and High-risk Patients With HNSCC Greater Than 6 Weeks After Surgery
NCT06607406
Remote Hypertension Management for Black Patients
NCT06527794
Evaluation of a Health System Integrated Model for Postpartum Education and Support in Rural Populations
NCT06682520
Taste Alterations Study
NCT06669416
Pediatric and Caregiver Traumatic Stress Intervention (PACTS)
NCT06366282
Cranial Ultrasound for Point of Care Intracranial Pathology Detection in Pediatrics
NCT06697808
Optimization of Postoperative Bowel Habits
NCT06335797
Comparing Magnesium 2g Versus 4g Versus Placebo in the Incidence of Treating AFF RVR
NCT06376916
WATD and Cancer-Related Fatigue: A Study For Patients Undergoing Anti-Cancer Treatment
NCT06291324
Topical Treatment for Atopic Dermatitis
NCT06244212
Single Versus Dual Implant Fixation of Distal Femur Fractures
NCT06286670
Post-Operative Cesarean Section Cosmesis
NCT06412978
Primary Subtalar Arthrodesis for Calcaneal Fractures
NCT06249126
Emergency Medicine Cardiovascular Risk Assessment for Lipid Disorders Trial
NCT06488105
BE WELL With Migraine: Brain Education and WELLness With Migraine
NCT05987592
E-PRIME For Children With Medical Complexity
NCT06216548
BRAIN-HEART Ultrasound Study Normative Values for Transcranial Doppler Based Cerebral Blood Flow Assessment
NCT05924503
Serotonin-norepinephrine Reuptake Inhibitor in Prophylaxis of Depression Following Fragility Fractures
NCT05851898
Intramedullary Calcium Sulfate Antibiotic Depot
NCT05766670
Microneedling vs Dermabrasion for Early Facial Scar Resurfacing
NCT06171386
LCI-PED-NOS-EXER-001: Exercise in Pediatric Oncology Patients
NCT05058508
Incremental Hemodialysis: The TwoPlus Trial
NCT05828823
CAPACITY (Cardiac Amyloidosis and Physical ACtivITY) Study
NCT06096675
Immersive Healing: The Therapeutic Potential of Virtual Reality
NCT06077227
Human Immunodeficiency Virus (HIV) Food Insecurities
NCT04943861
A Study Evaluating the Effect of Frozen-Section Directed Excision Surgery on Vulvar Dysplasia
NCT05934851
CARE-CP (Testing a Cardiovascular Ambulatory Rapid Evaluation for Patients With Chest Pain)
NCT05897632
Reducing Risk for Infective Endocarditis
NCT05721781
Reducing the Incidence of Symptomatic Brain Metastases With MRI Surveillance
NCT05692635
Reducing Tobacco Smoking: a Transcranial Direct Current Stimulation (TDCS) Telehealth Study
NCT05460676
Neoadjuvant Chemotherapy for Borderline Resectable and Locally Advanced Pancreatic Adenocarcinoma
NCT05825066
Quick Start Durvalumab Following Chemoradiation for Stage III Nonsmall Cell Lung Cancer
NCT05696782
Take A Break - Rural
NCT05790486
Comparing Single vs Multiple Dose Radiation for Cancer Patients With Brain Metastasis and Receiving Immunotherapy
NCT05703269
Identifying Challenges to Healthy Aging in Persons With Human Immunodeficiency Virus (HIV) Age 50 and Older
NCT05858034
REmotely-delivered Supportive Programs for Improving Surgical Pain and disTrEss
NCT05625360
Bone, Exercise, Alendronate, and Caloric Restriction
NCT05764733
Repurposing Low-Dose Clonidine for PTSD in Veterans
NCT04877093
Implantation Of Vaginal Construct For Patients With Vaginal Aplasia
NCT05675722
Prophylactic Antibiotic Coated Nail to Prevent Infection: A Clinical Trial
NCT05421741
Collaborative Care for Anxiety and Depression in Epilepsy
NCT05559749
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 77 |
| Phase 2 | 103 |
| Phase 3 | 12 |
| Phase 4 | 81 |
Therapeutic Areas
What the Pipeline for Wake Forest University Health Sciences Shows
According to the ClinicalTrials.gov registry, Wake Forest University Health Sciences is linked to 1,061 US clinical trials across every stage of research activity. Of those, 840 studies are currently recruiting — about 79% of the sponsor's indexed portfolio — and 181 are already marked complete, representing roughly 17% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
The phase mix for Wake Forest University Health Sciences reports 93 late-stage studies (Phase 3 and Phase 4 combined) and 180 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
The top therapeutic focus area indexed for Wake Forest University Health Sciences is Breast Cancer with 9 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology — how this data is sourced, computed, and verified.