Wake Forest University Health Sciences

1,061 total trials 840 currently recruiting 181 completed

Trial Pipeline

RECRUITING

Role of Mitochondrial Bioenergetics in Resilience for Gynecologic Cancer

NCT07046936

RECRUITING Phase 2

Metformin Hydrochloride in Combination With Standard of Care Systemic Therapy in Previously Untreated Advanced Unresectable or Metastatic Soft Tissue Sarcoma

NCT07291297

RECRUITING NA

Intra-abdominal Pressure (IAP) During PFA Treatment of A-fib/ A-Flutter

NCT06876896

RECRUITING Phase 1

Safety and Feasibility Study of Autologous Engineered Urethral Constructs for the Treatment of Strictures

NCT03258658

RECRUITING

Pre-malignant States to Hematologic Malignancies in Firefighters

NCT06870760

RECRUITING NA

A Novel Dialectical Behavior Therapy Brief Group Intervention for Cigarette Smoking by Patients With Cancer: An Open Clinical Trial

NCT07119489

RECRUITING

Assessing and Addressing Health-Related Social Needs Among Families of Children With Cancer

NCT07278414

RECRUITING NA

Optimizing Self-Monitoring Feedback Delivery for the Treatment of Overweight and Obesity

NCT07227051

RECRUITING NA

ONC-MM-2407: The Effect of Virtual Reality Headsets on Pain and Anxiety in the Peri and Post Bone Marrow Biopsy Period

NCT07203534

RECRUITING NA

Vital Coach: A Study of Resiliency in Medical Students

NCT07342673

RECRUITING

Surgical Thromboprophylaxis Practices in Oncology Patients Within the NCORP Network, STOP-VTE Study

NCT07215624

RECRUITING NA

Evaluation of Flexible Conductive Hearing Aids

NCT07222202

RECRUITING Phase 3

Effectiveness of Magnesium in Addition to Prochlorperazine for the Treatment of Migraines

NCT06904287

RECRUITING Phase 4

Pilot Study of Fisetin to Improve Fatigue Among Older Adult Cancer Survivors

NCT06819254

RECRUITING Phase 3

R.E.C.K vs Exparel in Robotic Nephrectomy

NCT07092566

RECRUITING NA

Deprescribing in Outpatient Internal Medicine Practices

NCT07226960

RECRUITING Phase 1

Inhaled Nitric Oxide in Acute Ischemic Stroke Patients Undergoing Mechanical Thrombectomy

NCT05871606

RECRUITING NA

Comparison of Urinary Flow Study

NCT06918067

RECRUITING Phase 2

Intranasal and Intravenous Oxytocin for Analgesia to Noxious Heat Pain

NCT07053774

RECRUITING

Oral Gastric Suctioning Effect on Transesophageal Echo

NCT07209293

RECRUITING

A Skin Image Reference Tool to Aid Healthcare Providers' Diagnosis

NCT07033169

RECRUITING NA

Bracing and Reconstruction of the Anterior Cruciate Ligament for Efficacy Trial

NCT06942754

RECRUITING NA

Education & Mentorship of Advanced Practice Providers to Increase Community-based Research Within the NCORP Network, COACH-APP Trial

NCT06904391

RECRUITING NA

Bump the Lump - Intervention for the Treatment of Globus Pharyngeus

NCT06762444

RECRUITING Phase 2

A Single-arm, Phase II Clinical Trial of ASPIRin to prEvent Venous Thromboembolism in Patients With Advanced Germ Cell Tumors Receiving Chemotherapy

NCT06866964

RECRUITING

Validation of Chronic Obstructive Pulmonary Disease (COPD) Algorithm

NCT07223749

RECRUITING

LCI-SAR-BSTS-CTDNA-001: Circulating Tumor DNA Liquid Biopsy in Sarcoma Patients

NCT06958107

RECRUITING NA

Sequential Multiple Assignment Randomized Trial to Reduce Food Insecurity

NCT07031739

RECRUITING NA

Quitting Matters Human Immunodeficiency Virus Hybrid Trial

NCT06883097

RECRUITING NA

Standardized Application of Feeding Evaluations Using SMART Tool

NCT07136610

RECRUITING NA

Enhancing Physical Function in Older Adults With Chronic Kidney Disease

NCT06738394

RECRUITING

The Better, Harder, Faster, Stronger Study

NCT07220512

RECRUITING NA

Evaluating Microarray Pharmacogenetic Testing in Cancer Patients

NCT06489041

RECRUITING NA

Nurturing Outreach for Understanding and Reducing Inpatient Security of Health

NCT07010289

RECRUITING NA

ONC-LEUK-2406: The Impact of Systematic Financial Navigation in Acute Myeloid Leukemia

NCT06945042

RECRUITING Phase 4

Identifying and Treating Depression in the Orthopaedic Trauma Population

NCT05976347

RECRUITING

Emergency Medical Services (EMS) Telehealth to Speed STEMI Reperfusion

NCT06945900

RECRUITING NA

Brain-Gut Yoga for Functional Dyspepsia and Gastroparesis (FD-GP)

NCT06732453

RECRUITING NA

Feasibility of an ADAPTive Intervention to Improve Food Security and Maternal-Child Health

NCT06942598

RECRUITING NA

Comparison of Single vs. Dual Perclose Devices for Large-Bore Access Closure in TAVR

NCT06871774

RECRUITING

Development of Quantitative Muscle Imaging as a Biomarker of Disease Endpoints in Myotonic Dystrophy

NCT07362875

RECRUITING NA

COmmunities Aligned to Reduce Concussion and Head Impact Exposure

NCT06624202

RECRUITING NA

M-PART in Head and Neck Cancer Patients Treated With KeraStat Cream for Acute Radiation Dermatitis

NCT06441266

RECRUITING NA

Evaluating the Effect of Surgical Drain Securement on Patient Quality of Life and Postoperative Drain-related Complications

NCT06916286

RECRUITING NA

Project neuroARTEMIS

NCT06814275

RECRUITING Phase 4

Seizure Prevention in Traumatic Brain Injury With Levetiracetam and Lacosamide

NCT06866691

RECRUITING

Toxicity Genetic Determinants and Response to Azacitidine and Venetoclax in AML

NCT06580106

RECRUITING

Cancer-related Fatigue During Maintenance Immunotherapy for Non-small Cell Lung Cancer (NSCLC): a Qualitative Study

NCT06567704

RECRUITING NA

Transcranial Magnetic Stimulation (TMS) Effects Using Magnetoencephalography (MEG) Study

NCT06770556

RECRUITING

Patient Descriptors Of Cancer-Related Fatigue: A Mixed Methods Pilot Study Of Cancer Survivors

NCT06634381

RECRUITING

CHAAMP (CHArlotte Advocate MGUS Project) Internal Pilot Study

NCT06644625

RECRUITING Phase 2

Nivolumab in Multiple Myeloma Patients After Idecabtagene Vicleucel

NCT06523621

RECRUITING

COPD Care Pathway Among Patients With Cancer

NCT05984680

RECRUITING

Discharge Medication Use Post-Operatively in GU Cancer Patients

NCT06795087

RECRUITING NA

Efficacy of 3D-Printed Mouth Splints

NCT06801535

RECRUITING Early Phase 1

Safety and Efficacy of Aloe Vera in the Management of the Symptoms of Interstitial Cystitis

NCT04734106

RECRUITING NA

Telehealth Intervention for Improving Distress and Financial Toxicity in the Caregivers

NCT06709404

RECRUITING

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

NCT06418204

RECRUITING

Evaluation of the Pathobiology of CALR-mutated MPN Cells

NCT06480591

RECRUITING NA

Postoperative Radiotherapy for Intermediate- and High-risk Patients With HNSCC Greater Than 6 Weeks After Surgery

NCT06607406

RECRUITING NA

Remote Hypertension Management for Black Patients

NCT06527794

RECRUITING NA

Evaluation of a Health System Integrated Model for Postpartum Education and Support in Rural Populations

NCT06682520

RECRUITING NA

Taste Alterations Study

NCT06669416

RECRUITING NA

Pediatric and Caregiver Traumatic Stress Intervention (PACTS)

NCT06366282

RECRUITING

Cranial Ultrasound for Point of Care Intracranial Pathology Detection in Pediatrics

NCT06697808

RECRUITING NA

Optimization of Postoperative Bowel Habits

NCT06335797

RECRUITING Phase 3

Comparing Magnesium 2g Versus 4g Versus Placebo in the Incidence of Treating AFF RVR

NCT06376916

RECRUITING

WATD and Cancer-Related Fatigue: A Study For Patients Undergoing Anti-Cancer Treatment

NCT06291324

RECRUITING NA

Topical Treatment for Atopic Dermatitis

NCT06244212

RECRUITING NA

Single Versus Dual Implant Fixation of Distal Femur Fractures

NCT06286670

RECRUITING NA

Post-Operative Cesarean Section Cosmesis

NCT06412978

RECRUITING NA

Primary Subtalar Arthrodesis for Calcaneal Fractures

NCT06249126

RECRUITING Phase 2

Emergency Medicine Cardiovascular Risk Assessment for Lipid Disorders Trial

NCT06488105

RECRUITING NA

BE WELL With Migraine: Brain Education and WELLness With Migraine

NCT05987592

RECRUITING NA

E-PRIME For Children With Medical Complexity

NCT06216548

RECRUITING

BRAIN-HEART Ultrasound Study Normative Values for Transcranial Doppler Based Cerebral Blood Flow Assessment

NCT05924503

RECRUITING Phase 4

Serotonin-norepinephrine Reuptake Inhibitor in Prophylaxis of Depression Following Fragility Fractures

NCT05851898

RECRUITING Phase 3

Intramedullary Calcium Sulfate Antibiotic Depot

NCT05766670

RECRUITING NA

Microneedling vs Dermabrasion for Early Facial Scar Resurfacing

NCT06171386

RECRUITING NA

LCI-PED-NOS-EXER-001: Exercise in Pediatric Oncology Patients

NCT05058508

RECRUITING NA

Incremental Hemodialysis: The TwoPlus Trial

NCT05828823

RECRUITING NA

CAPACITY (Cardiac Amyloidosis and Physical ACtivITY) Study

NCT06096675

RECRUITING NA

Immersive Healing: The Therapeutic Potential of Virtual Reality

NCT06077227

RECRUITING NA

Human Immunodeficiency Virus (HIV) Food Insecurities

NCT04943861

RECRUITING NA

A Study Evaluating the Effect of Frozen-Section Directed Excision Surgery on Vulvar Dysplasia

NCT05934851

RECRUITING NA

CARE-CP (Testing a Cardiovascular Ambulatory Rapid Evaluation for Patients With Chest Pain)

NCT05897632

RECRUITING NA

Reducing Risk for Infective Endocarditis

NCT05721781

RECRUITING Phase 2

Reducing the Incidence of Symptomatic Brain Metastases With MRI Surveillance

NCT05692635

RECRUITING NA

Reducing Tobacco Smoking: a Transcranial Direct Current Stimulation (TDCS) Telehealth Study

NCT05460676

RECRUITING Phase 2

Neoadjuvant Chemotherapy for Borderline Resectable and Locally Advanced Pancreatic Adenocarcinoma

NCT05825066

RECRUITING Phase 2

Quick Start Durvalumab Following Chemoradiation for Stage III Nonsmall Cell Lung Cancer

NCT05696782

RECRUITING NA

Take A Break - Rural

NCT05790486

RECRUITING NA

Comparing Single vs Multiple Dose Radiation for Cancer Patients With Brain Metastasis and Receiving Immunotherapy

NCT05703269

RECRUITING NA

Identifying Challenges to Healthy Aging in Persons With Human Immunodeficiency Virus (HIV) Age 50 and Older

NCT05858034

RECRUITING Phase 3

REmotely-delivered Supportive Programs for Improving Surgical Pain and disTrEss

NCT05625360

RECRUITING Phase 4

Bone, Exercise, Alendronate, and Caloric Restriction

NCT05764733

RECRUITING Phase 3

Repurposing Low-Dose Clonidine for PTSD in Veterans

NCT04877093

RECRUITING Phase 1

Implantation Of Vaginal Construct For Patients With Vaginal Aplasia

NCT05675722

RECRUITING Phase 4

Prophylactic Antibiotic Coated Nail to Prevent Infection: A Clinical Trial

NCT05421741

RECRUITING NA

Collaborative Care for Anxiety and Depression in Epilepsy

NCT05559749

Phase Distribution

PhaseTrial count
Phase 1 77
Phase 2 103
Phase 3 12
Phase 4 81

What the Pipeline for Wake Forest University Health Sciences Shows

According to the ClinicalTrials.gov registry, Wake Forest University Health Sciences is linked to 1,061 US clinical trials across every stage of research activity. Of those, 840 studies are currently recruiting — about 79% of the sponsor's indexed portfolio — and 181 are already marked complete, representing roughly 17% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

The phase mix for Wake Forest University Health Sciences reports 93 late-stage studies (Phase 3 and Phase 4 combined) and 180 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

The top therapeutic focus area indexed for Wake Forest University Health Sciences is Breast Cancer with 9 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial