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NCT05465538 · ClinicalTrials.gov registry record · Phase 1

SV2A in Older Adults

A Phase 1 study of Cannabis Use, sponsored by Yale University.

Recruiting
Registry status
Phase 1
Development phase
24
Enrollment target
1
Study location

NCT05465538: Recruiting Phase 1 study of Cannabis Use, sponsored by Yale University.

NCT05465538 is a Phase 1 study of Cannabis Use that is actively recruiting participants, run by Yale University. The registered enrollment target is 24 participants, below the 279-participant average among 44 other Cannabis Use trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05465538, a Phase 1 study of Cannabis Use, is actively recruiting participants, sponsored by Yale University.

RECRUITING
Registry status
Phase 1
Development phase
24 participants
Enrollment target
1
Study location

Study Summary

The aim of the study is to examine the effect of cannabis use on brain synaptic density among older adults using \[11C\]UCB-J PET imaging.

Primary Outcome

Measure of synaptic density in the hippocampus

Conditions Studied

Interventions

  • DRUG [11C]UCB-J PET

Study Locations (1)

Connecticut

  • Conneticut Mental Health Center - New Haven

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2022-07-06
Est. Completion 2027-09-30
Phase Phase 1
Yale University

1,492 total trials

What NCT05465538 shows while recruiting

NCT05465538 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 279-participant average among 44 other Cannabis Use trials with a reported enrollment target (91% lower).

The record links to 1 condition, with Cannabis Use appearing as the primary indexed condition, and to 1 intervention - of which [11C]UCB-J PET is the first listed.

NCT05465538 reports a single indexed study location in Connecticut.

Frequently Asked Questions

What is clinical trial NCT05465538 about?

NCT05465538 is a clinical study titled "SV2A in Older Adults". The aim of the study is to examine the effect of cannabis use on brain synaptic density among older adults using \[11C\]UCB-J PET imaging.

What is the current status of trial NCT05465538?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2022-07-06. Estimated completion is 2027-09-30.

What conditions does trial NCT05465538 study?

This clinical trial studies the following conditions: Cannabis Use.

What interventions are being tested in trial NCT05465538?

The interventions under investigation include: [11C]UCB-J PET (DRUG).

Who is sponsoring clinical trial NCT05465538?

This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05465538 being conducted?

This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Cannabis Use

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05465538's enrollment target sits among peer trials

24 41st of 44 higher than 4 of 44 other Cannabis Use trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Cannabis Use trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05465538, the US trial registry maintained by the National Library of Medicine. NCT05465538 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.