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Eosinophilic Esophagitis
Open-data reference.
45 US clinical trials · 14 currently recruiting
Active & Recent Trials
A Registry for the Food Allergy Community
Food Allergy Research & Education
NCT04653324
Indiana University Gastrointestinal Motility Diagnosis Registry
Indiana University
NCT04506593
Natural History and Genetics of Food Allergy and Related Conditions
National Institute of Allergy and Infectious Diseases (NIAID)
NCT02504853
Characteristics and Inflammatory Markers in Children with Eosinophilic Esophagitis (EoE)
University of California, San Diego
NCT03980886
OMEGA: Outcome Measures in Eosinophilic Gastrointestinal Disorders Across the Ages
Children's Hospital Medical Center, Cincinnati
NCT02523118
Eosinophilic Gastrointestinal Disorders Registry
Ann & Robert H Lurie Children's Hospital of Chicago
NCT05199532
Once Daily Versus Twice Daily Budesonide Orodispersible Tablets for Induction of Remission in EoE
Dr. Falk Pharma
NCT06596252
A Study in Adult Participants With EoE to Evaluate Vonoprazan 20 mg Compared to Placebo After 12 Weeks and to Evaluate Vonoprazan 20 mg Up to 24 Weeks
Phathom Pharmaceuticals
NCT06851559
Dupilumab Versus Topical Corticosteroid Effectiveness - Comparison in the Treatment of Stenotic EoE
University of Colorado, Denver
NCT06705387
The Esophageal String Test as a Diagnostic Screening Tool for Eosinophilic Esophagitis Among Africans With Dysphagia in Mali and the United States
National Institute of Allergy and Infectious Diseases (NIAID)
NCT07027826
Utility of Mucosal Impedance Device in Chronic Esophageal Disorders:
Medical College of Wisconsin
NCT07227506
Patient-Centered Decision Support for Eosinophilic Esophagitis
University of Michigan
NCT06817213
Zemaira Eosinophilic Esophagitis Pilot Study
Children's Hospital Medical Center, Cincinnati
NCT05485155
Changes in Esophageal Distensibility With Proton Pump Inhibitors in Patients With Esophageal Eosinophilia: A Pilot Study
Indiana University
NCT03312686
Risk Factors and Biomarkers for Diagnosis and Treatment of EoE
University of North Carolina, Chapel Hill
NCT01988285
Esophageal String Test in Eosinophilic Esophagitis
University of Colorado, Denver
NCT02008903
Efficacy and Safety of Tezepelumab in Patients With Eosinophilic Esophagitis
AstraZeneca
NCT05583227
Safety Study of CC-93538 in Adult and Adolescent Participants With Eosinophilic Esophagitis
Celgene
NCT04991935
Prospective Database for Eosinophilic Esophagitis (EoE) of Pediatric Population
Ann & Robert H Lurie Children's Hospital of Chicago
NCT05176249
The Immune Directed Individualized Elimination Therapy (iDIET) Study
University of North Carolina, Chapel Hill
NCT05543512
Using Spectrally Encoded Confocal Microscopy (SECM) to Image the Esophagus
Massachusetts General Hospital
NCT02202590
Proton Pump Inhibitor (PPI) Response in Eosinophilic Esophagitis Assessed by Transnasal Endoscopy (TNE)
University of Colorado, Denver
NCT04149470
Inflammatory Mediators as Potential Non-Invasive Biomarkers in Subjects With Eosinophilic Esophagitis
Ann & Robert H Lurie Children's Hospital of Chicago
NCT03822325
A Prospective Study of the Four Food Elimination Diet for Treatment of Eosinophilic Esophagitis
Ann & Robert H Lurie Children's Hospital of Chicago
NCT05176262
Morphological Markers of Gastroesophageal Reflux Disease (GERD)
Baylor College of Medicine
NCT01921686
Cow's Milk Elimination for Treatment of Eosinophilic Esophagitis
Ann & Robert H Lurie Children's Hospital of Chicago
NCT05083156
Efficacy of Low-Dose Topical Steroids in Maintaining Remission of Eosinophilic Esophagitis in Children
Ann & Robert H Lurie Children's Hospital of Chicago
NCT05309590
Study to Determine the Efficacy and Safety of Dupilumab in Adult and Adolescent Patients With Eosinophilic Esophagitis (EoE)
Regeneron Pharmaceuticals
NCT03633617
Efficacy and Safety Study of Reslizumab to Treat Eosinophilic Esophagitis in Subjects Aged 5 to 18 Years
Ception Therapeutics
NCT00538434
Comparing Anesthetic Techniques in Children Having Esophagogastroduodenoscopies
Children's Hospital Medical Center, Cincinnati
NCT02038894
Efficacy and Safety APT-1011 in Adult Subjects With Eosinophilic Esophagitis (EoE) (FLUTE-2)
Ellodi Pharmaceuticals
NCT04281108
A Study to Assess the Safety and Efficacy of Oral Etrasimod in Adult Participants With Eosinophilic Esophagitis
Pfizer
NCT04682639
Dose Ranging Study of RPC4046 in Eosinophilic Esophagitis
Celgene
NCT02098473
The Role Of Gastroesophageal Reflux Disease (GERD) in Eosinophilic Esophagitis
Mayo Clinic
NCT00728481
A Study of Flovent in Patients With Eosinophilic Esophagitis
Marc Rothenberg, MD
NCT00426283
Efficacy and Safety of QAX576 in Patients With Eosinophilic Esophagitis
Novartis Pharmaceuticals
NCT01022970
Safety and Tolerability Study of Oral EUR-1100 to Treat Eosinophilic Esophagitis
Forest Laboratories
NCT01386112
Cytosponge and Dietary Therapy in EoE
Mayo Clinic
NCT02599558
A Food Additive Removal Diet for Pediatric Eosinophilic Esophagitis
Nemours Children's Clinic
NCT03657771
Efficacy of Dupilumab on Facilitated Food Introduction in Eosinophilic Esophagitis
Children's Hospital of Philadelphia
NCT05247866
Use of Esophageal String Test to Understand Symptoms, Inflammation, and Function in Eosinophilic Esophagitis
University of Colorado, Denver
NCT03305653
Oral Cromolyn Sodium for the Treatment of Eosinophilic Esophagitis
University of Tennessee
NCT02371941
a4b7 Integrin in Eosinophilic Esophagitis
Massachusetts General Hospital
NCT02546219
Radiation Dose in Humans From Orally Administered Tc99m-Heparin
University of Utah
NCT04069429
Testing Effectiveness of Losartan in Patients With EoE With or Without a CTD
Children's Hospital Medical Center, Cincinnati
NCT01808196
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 2 |
| Phase 2 | 10 |
| Phase 3 | 5 |
| Phase 4 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Eosinophilic Esophagitis Trial Landscape
ClinicalTrials.gov lists 45 US studies indexed under Eosinophilic Esophagitis, and 14 of those are currently open to recruitment — roughly 31% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Eosinophilic Esophagitis shows 8 late-stage studies (Phase 3 and Phase 4 combined) alongside 12 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Eosinophilic Esophagitis is led by Ann & Robert H Lurie Children's Hospital of Chicago with 6 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 45 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Eosinophilic Esophagitis?
PlainTrial tracks 45 US clinical trials for Eosinophilic Esophagitis, of which 14 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Eosinophilic Esophagitis?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.