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Eosinophilic Esophagitis: full-pipeline trial registry
14 of 45 indexed Eosinophilic Esophagitis trials are currently recruiting.
Corpus placement: #323 of 28,707 conditions by registered trial count.
45 US clinical trials · 14 currently recruiting · #323 of 28,707 conditions by registered trial count
Eosinophilic Esophagitis: 45 US clinical trials tracked, 14 recruiting.
Eosinophilic Esophagitis is the subject of 45 registered US clinical trials on ClinicalTrials.gov, 14 of them currently open to new participants. 8 are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most active sponsor is Ann & Robert H Lurie Children's Hospital of Chicago, running 6 of these trials.
Enrollment posture brief
Registry condition eosinophilic-esophagitis
OPEN 14 | RECR 31% | LATE 8 | EARLY 12 | RANK #323 | SPON 6
Volume-matched condition peers
Nearest open-share peer: Chronic Kidney Disease (31% recruiting · 103 trials)
Eosinophilic Esophagitis lists 14 open slots (31% of 45 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Eosinophilic Esophagitis on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Eosinophilic Esophagitis is recruiting below its size-band peers.
14 of 45 indexed trials (31.1%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Eosinophilic Esophagitis trials is spread across many organizations.
Ann & Robert H Lurie Children's Hospital of Chicago accounts for 6 of 45 trials (13.3%). 28 distinct sponsors appear on at least one study for this condition label.
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Typical Eosinophilic Esophagitis enrolment sits around 80 participants.
Median target enrolment is 80 among the 45 trials that report a genuine target (sentinel values excluded). 26 of those (57.8%) plan for fewer than 100 participants.
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Eosinophilic Esophagitis splits between interventional and observational designs.
28 interventional and 17 observational studies make up this index (62.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
45 total, page 1 of 1
A Registry for the Food Allergy Community
Food Allergy Research & Education
NCT04653324
Indiana University Gastrointestinal Motility Diagnosis Registry
Indiana University
NCT04506593
Natural History and Genetics of Food Allergy and Related Conditions
National Institute of Allergy and Infectious Diseases (NIAID)
NCT02504853
Characteristics and Inflammatory Markers in Children with Eosinophilic Esophagitis (EoE)
University of California, San Diego
NCT03980886
OMEGA: Outcome Measures in Eosinophilic Gastrointestinal Disorders Across the Ages
Children's Hospital Medical Center, Cincinnati
NCT02523118
Eosinophilic Gastrointestinal Disorders Registry
Ann & Robert H Lurie Children's Hospital of Chicago
NCT05199532
Once Daily Versus Twice Daily Budesonide Orodispersible Tablets for Induction of Remission in EoE
Dr. Falk Pharma
NCT06596252
A Study in Adult Participants With EoE to Evaluate Vonoprazan 20 mg Compared to Placebo After 12 Weeks and to Evaluate Vonoprazan 20 mg Up to 24 Weeks
Phathom Pharmaceuticals
NCT06851559
Dupilumab Versus Topical Corticosteroid Effectiveness - Comparison in the Treatment of Stenotic EoE
University of Colorado, Denver
NCT06705387
The Esophageal String Test as a Diagnostic Screening Tool for Eosinophilic Esophagitis Among Africans With Dysphagia in Mali and the United States
National Institute of Allergy and Infectious Diseases (NIAID)
NCT07027826
Utility of Mucosal Impedance Device in Chronic Esophageal Disorders:
Medical College of Wisconsin
NCT07227506
Patient-Centered Decision Support for Eosinophilic Esophagitis
University of Michigan
NCT06817213
Zemaira Eosinophilic Esophagitis Pilot Study
Children's Hospital Medical Center, Cincinnati
NCT05485155
Changes in Esophageal Distensibility With Proton Pump Inhibitors in Patients With Esophageal Eosinophilia: A Pilot Study
Indiana University
NCT03312686
Risk Factors and Biomarkers for Diagnosis and Treatment of EoE
University of North Carolina, Chapel Hill
NCT01988285
Esophageal String Test in Eosinophilic Esophagitis
University of Colorado, Denver
NCT02008903
Efficacy and Safety of Tezepelumab in Patients With Eosinophilic Esophagitis
AstraZeneca
NCT05583227
Safety Study of CC-93538 in Adult and Adolescent Participants With Eosinophilic Esophagitis
Celgene
NCT04991935
Prospective Database for Eosinophilic Esophagitis (EoE) of Pediatric Population
Ann & Robert H Lurie Children's Hospital of Chicago
NCT05176249
The Immune Directed Individualized Elimination Therapy (iDIET) Study
University of North Carolina, Chapel Hill
NCT05543512
Using Spectrally Encoded Confocal Microscopy (SECM) to Image the Esophagus
Massachusetts General Hospital
NCT02202590
Proton Pump Inhibitor (PPI) Response in Eosinophilic Esophagitis Assessed by Transnasal Endoscopy (TNE)
University of Colorado, Denver
NCT04149470
Inflammatory Mediators as Potential Non-Invasive Biomarkers in Subjects With Eosinophilic Esophagitis
Ann & Robert H Lurie Children's Hospital of Chicago
NCT03822325
A Prospective Study of the Four Food Elimination Diet for Treatment of Eosinophilic Esophagitis
Ann & Robert H Lurie Children's Hospital of Chicago
NCT05176262
Morphological Markers of Gastroesophageal Reflux Disease (GERD)
Baylor College of Medicine
NCT01921686
Cow's Milk Elimination for Treatment of Eosinophilic Esophagitis
Ann & Robert H Lurie Children's Hospital of Chicago
NCT05083156
Efficacy of Low-Dose Topical Steroids in Maintaining Remission of Eosinophilic Esophagitis in Children
Ann & Robert H Lurie Children's Hospital of Chicago
NCT05309590
Study to Determine the Efficacy and Safety of Dupilumab in Adult and Adolescent Patients With Eosinophilic Esophagitis (EoE)
Regeneron Pharmaceuticals
NCT03633617
Efficacy and Safety Study of Reslizumab to Treat Eosinophilic Esophagitis in Subjects Aged 5 to 18 Years
Ception Therapeutics
NCT00538434
Comparing Anesthetic Techniques in Children Having Esophagogastroduodenoscopies
Children's Hospital Medical Center, Cincinnati
NCT02038894
Efficacy and Safety APT-1011 in Adult Subjects With Eosinophilic Esophagitis (EoE) (FLUTE-2)
Ellodi Pharmaceuticals
NCT04281108
A Study to Assess the Safety and Efficacy of Oral Etrasimod in Adult Participants With Eosinophilic Esophagitis
Pfizer
NCT04682639
Dose Ranging Study of RPC4046 in Eosinophilic Esophagitis
Celgene
NCT02098473
The Role Of Gastroesophageal Reflux Disease (GERD) in Eosinophilic Esophagitis
Mayo Clinic
NCT00728481
A Study of Flovent in Patients With Eosinophilic Esophagitis
Marc Rothenberg, MD
NCT00426283
Efficacy and Safety of QAX576 in Patients With Eosinophilic Esophagitis
Novartis Pharmaceuticals
NCT01022970
Safety and Tolerability Study of Oral EUR-1100 to Treat Eosinophilic Esophagitis
Forest Laboratories
NCT01386112
Cytosponge and Dietary Therapy in EoE
Mayo Clinic
NCT02599558
A Food Additive Removal Diet for Pediatric Eosinophilic Esophagitis
Nemours Children's Clinic
NCT03657771
Efficacy of Dupilumab on Facilitated Food Introduction in Eosinophilic Esophagitis
Children's Hospital of Philadelphia
NCT05247866
Use of Esophageal String Test to Understand Symptoms, Inflammation, and Function in Eosinophilic Esophagitis
University of Colorado, Denver
NCT03305653
Oral Cromolyn Sodium for the Treatment of Eosinophilic Esophagitis
University of Tennessee
NCT02371941
a4b7 Integrin in Eosinophilic Esophagitis
Massachusetts General Hospital
NCT02546219
Radiation Dose in Humans From Orally Administered Tc99m-Heparin
University of Utah
NCT04069429
Testing Effectiveness of Losartan in Patients With EoE With or Without a CTD
Children's Hospital Medical Center, Cincinnati
NCT01808196
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 10 |
| Phase 3 | 5 |
| Phase 4 | 3 |
Top Sponsors
Named interventions
Most-linked intervention names on Eosinophilic Esophagitis records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Eosinophilic Esophagitis trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Eosinophilic Esophagitis page
45 registered trials, 14 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 14 Eosinophilic Esophagitis trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Ann & Robert H Lurie Children's Hospital of Chicago sponsors the most Eosinophilic Esophagitis trials on record, review their full trial history before evaluating a specific study. See Ann & Robert H Lurie Children's Hospital of Chicago's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Eosinophilic Esophagitis condition card totals 45 registered trials; most-linked intervention Placebo; top US site state Illinois. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.