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NCT05396638 · ClinicalTrials.gov registry record · NA
Characterization of Endocannabinoid and Endogenous Opioid Levels in Adolescents With Cannabis Use Disorder
A NA study of Cannabis Use, sponsored by University of Colorado, Denver.
- Recruiting
- Registry status
- NA
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT05396638: Recruiting NA study of Cannabis Use, sponsored by University of Colorado, Denver.
NCT05396638 is a NA study of Cannabis Use that is actively recruiting participants, run by University of Colorado, Denver. The registered enrollment target is 30 participants, below the 279-participant average among 44 other Cannabis Use trials with a reported enrollment target (89% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05396638, a NA study of Cannabis Use, is actively recruiting participants, sponsored by University of Colorado, Denver.
- RECRUITING
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
This project seeks to learn more about the effects of cannabis use on the endocannabinoid system and endogenous opioid systems in adolescents to address a fundamental gap in knowledge and identify biomarkers that may help distinguish youth who relapse from youth who remain sober.
Primary Outcome
Cannabinoid levels in blood: Our primary measure will be 11-nor-carboxy-Δ9-tetrahydrocannabinol (THCCOOH) concentrations in whole blood, which have been demonstrated to be a reliable quantitative measure of cannabis use over the past few weeks35. We will measure an additional 10 cannabinoids \[THC, 11-hydroxy-THC, THC-glucuronide, cannabidiol (CBD), cannabinol (CBN), cannabigerol (CBG), cannabichromene (CBC), cannabidivarin (CBDV), tetrahydro-cannabivarin (THCV), and THCV-COOH\]34, which will be
Conditions Studied
Interventions
- BEHAVIORAL Contingency Management
Study Locations (1)
Colorado
- University of Colorado Anschutz Medical Campus - Aurora
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2022-10-13 |
| Est. Completion | 2025-12 |
| Phase | NA |
What NCT05396638 shows while recruiting
NCT05396638 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 279-participant average among 44 other Cannabis Use trials with a reported enrollment target (89% lower).
The record links to 1 condition, with Cannabis Use appearing as the primary indexed condition, and to 1 intervention - of which Contingency Management is the first listed.
NCT05396638 reports a single indexed study location in Colorado.
Frequently Asked Questions
What is clinical trial NCT05396638 about?
NCT05396638 is a clinical study titled "Characterization of Endocannabinoid and Endogenous Opioid Levels in Adolescents With Cannabis Use Disorder". This project seeks to learn more about the effects of cannabis use on the endocannabinoid system and endogenous opioid systems in adolescents to address a fundamental gap in knowledge and identify biomarkers that may help distinguish youth who relapse from youth who remain sober.
What is the current status of trial NCT05396638?
This trial is currently recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2022-10-13. Estimated completion is 2025-12.
What conditions does trial NCT05396638 study?
This clinical trial studies the following conditions: Cannabis Use.
What interventions are being tested in trial NCT05396638?
The interventions under investigation include: Contingency Management (BEHAVIORAL).
Who is sponsoring clinical trial NCT05396638?
This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05396638 being conducted?
This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cannabis Use
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05396638's enrollment target sits among peer trials
30 39th of 44 higher than 6 of 44 other Cannabis Use trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cannabis Use trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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