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NCT04998006 · ClinicalTrials.gov registry record
Alcohol and Cannabis Co-Use and the Gut-Brain Axis
A clinical trial of Inflammation and Cannabis Use, sponsored by University of Colorado, Denver.
- Completed
- Registry status
- 77
- Enrollment target
- 1
- Study location
NCT04998006: Completed study of Inflammation and Cannabis Use, sponsored by University of Colorado, Denver.
NCT04998006 is a study of Inflammation and Cannabis Use that has completed, run by University of Colorado, Denver. The registered enrollment target is 77 participants, below the 288-participant average among 132 other Inflammation trials with a reported enrollment target (73% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04998006, a study of Inflammation and Cannabis Use, has completed, sponsored by University of Colorado, Denver.
- COMPLETED
- Registry status
- 77 participants
- Enrollment target
- 1
- Study location
Study Summary
This observational study aims to improve our understanding of how legal market cannabis use impacts acute and long-term alcohol use, the microbiota-gut-brain-axis (MGBA), and neurobehavioral alcohol use phenotypes such as impulsivity, impaired cognitive functioning, and craving, among individuals who regularly use both alcohol and cannabis. Over a period of one month, subjects will participate in this three-visit study. Blood samples will be collected to allow for the assessment of inflammatory markers and cannabinoids, a fecal sample will be collected to allow for the analysis of the gut microbiome, and participants will complete cognitive and impulsivity tasks and provide craving ratings during the course of an alcohol self-administration procedure. Subjects will also participate in two 14-day daily diary data collection periods between lab sessions. Daily diary data collection will be used to assess the effects of cannabis use on alcohol use and craving longitudinally.
Primary Outcome
Total number of drinks consumed (out of 4) in a one-hour period.
Conditions Studied
Study Locations (1)
Colorado
- CU Anschutz School of Medicine - Aurora
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 77 participants |
| Start Date | 2022-02-25 |
| Est. Completion | 2024-12-23 |
What the finished NCT04998006 record still lists
NCT04998006 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 77 participants, a relatively small participant target, below the 288-participant average among 132 other Inflammation trials with a reported enrollment target (73% lower).
The record links to 3 conditions, with Inflammation appearing as the primary indexed condition, and to 0 interventions.
NCT04998006 reports a single indexed study location in Colorado.
Frequently Asked Questions
What is clinical trial NCT04998006 about?
NCT04998006 is a clinical study titled "Alcohol and Cannabis Co-Use and the Gut-Brain Axis". This observational study aims to improve our understanding of how legal market cannabis use impacts acute and long-term alcohol use, the microbiota-gut-brain-axis (MGBA), and neurobehavioral alcohol use phenotypes such as impulsivity, impaired cognitive functioning, and craving, among individuals wh...
What is the current status of trial NCT04998006?
This trial is currently completed. The enrollment target is 77 participants. The study started on 2022-02-25. Estimated completion is 2024-12-23.
What conditions does trial NCT04998006 study?
This clinical trial studies the following conditions: Inflammation, Cannabis Use, Alcohol Use.
Who is sponsoring clinical trial NCT04998006?
This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04998006 being conducted?
This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT04998006's enrollment target sits among peer trials
77 55th of 132 higher than 78 of 132 other Inflammation trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Inflammation trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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