VA Office of Research and Development

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, VA Office of Research and Development sits in the top decile of US sponsors by registered trial count (#11 of 15,742 sponsors by registered trial count).

1,668 total trials 291 currently recruiting 1108 completed early-phase tilt top decile by trial count

VA Office of Research and Development: 1,668 sponsored US clinical trials, 291 recruiting.

VA Office of Research and Development sponsors 1,668 registered US clinical trials on ClinicalTrials.gov, 291 of them currently recruiting, and 1,108 completed. 124 of these trials are in Phase 3-4 (later-stage) and 236 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Post Traumatic Stress Disorder, with 45 trials.

Top-decile sponsor footprint

VA Office of Research and Development ranks in the top decile of sponsors by registered trial count (#11 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 75/100

1,108 of 1,180 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (93.9%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,668 total, page 14 of 34

TERMINATED NA

Treating Stimulant Addiction With Repetitive Transcranial Magnetic Stimulation

NCT04228276

COMPLETED NA

Comparing Group Therapies for Veterans With Depression and PTSD

NCT03979040

COMPLETED

Novel EEG Coherence Biomarkers for PTSD Assessment

NCT04209387

COMPLETED

Enhancing Access to Insomnia (EASI) Care in VA PCMHI Clinics

NCT04350866

COMPLETED NA

Continuing the Conversation: Using Narrative Communication to Support Hypertension Self-management in African American Veterans

NCT03970590

COMPLETED NA

An Evaluation of MBSR and CBT for Veterans With Chronic Pain

NCT04486066

COMPLETED NA

Live Long Walk Strong (LLWS) Rehabilitation Program: What Features Improve Mobility Skills

NCT04026503

COMPLETED

Lower Back Biomechanics in Veterans With Non-Specific Low Back Pain

NCT04249453

TERMINATED Phase 2

Mechanisms of EPO-induced Hypertension

NCT03810911

COMPLETED Phase 2

Oxytocin to Treat PTSD

NCT04228289

COMPLETED NA

Caring Cards to and From Veterans: A Peer Approach to Suicide Prevention

NCT04486677

COMPLETED NA

Cognitive Behavioral Therapy to Improve Work and Wellness in Veterans With Mental Illness

NCT04504903

COMPLETED Phase 1

Strengths-based Linkage to Alcohol Care (SLAC) for Hazardous Drinkers in Primary Care

NCT05023317

COMPLETED NA

Caregiver Self-Management of Stress

NCT04337021

COMPLETED NA

Upper Limb Loss Perturbation Response

NCT04274218

COMPLETED NA

USS Training to Improve Social Function in People With Psychosis

NCT04557124

COMPLETED

Optimizing Cognitive Remediation

NCT04395157

COMPLETED NA

A Nurse-led Intervention to Extend the Veteran HIV Treatment Cascade for Cardiovascular Disease Prevention

NCT04545489

COMPLETED NA

Transcranial Magnetic Stimulation to Improve Functioning in Veterans With PTSD

NCT04207346

TERMINATED Phase 3

VA CoronavirUs Research and Efficacy Studies-1

NCT04539275

COMPLETED NA

Neuroplasticity in TBI and Schizophrenia

NCT03995368

COMPLETED NA

Powered Orthotic Exoskeleton Training in Stroke

NCT04241848

COMPLETED NA

Teaching Loved Ones to Help Veterans Optimize Their PTSD Care and Healing

NCT04241094

COMPLETED NA

Post-Hospital Intervention for Veterans With Comorbid Bipolar and Substance Use Disorders

NCT04127604

COMPLETED NA

Addressing Intimate Partner Violence Among Women Veterans

NCT04106193

COMPLETED NA

Stress, Emotion Regulation, and Alcohol in Women Veterans

NCT04393623

COMPLETED NA

Novel Training Environment to Normalize Altered Finger Force Direction Post Stroke

NCT03995069

COMPLETED NA

Amplify Gait to Improve Locomotor Engagement in Spinal Cord Injury

NCT04340063

COMPLETED NA

Transpelvic Magnetic Stimulation to Improve Urogenital Function

NCT04488068

COMPLETED NA

Virtual Pain Care Management (COVID-19)

NCT04539821

COMPLETED NA

MOVE!+UP: Testing a Tailored Weight Management Program for Veterans With PTSD

NCT04563741

COMPLETED NA

Comparing Individual Therapies for Veterans With Depression, PTSD, and Panic Disorder

NCT04293341

COMPLETED NA

Using Data-Driven Implementation Strategies to Improve the Quality of Cirrhosis Care

NCT04178096

COMPLETED NA

GOALS Cognitive Training Delivered to Aging Veterans in Person or Via Telehealth

NCT04111549

COMPLETED NA

The Impact of a Home-based Pulmonary Telerehabilitation Program in Acute Exacerbations of COPD

NCT03997513

COMPLETED NA

Bright Light Therapy for Residual Daytime Symptoms Associated With Obstructive Sleep Apnea

NCT04299009

COMPLETED NA

Electronic Proactive Outreach for Smokers With COPD

NCT04462289

COMPLETED

Tailored Approaches to Reduce Distress and Improve Self-Management for Veterans With Diabetes

NCT04587336

COMPLETED NA

Improving Patient-Provider Communication to Reduce Mental Health Disparities

NCT04515771

COMPLETED NA

Feasibility of Improving Sleep Apnea Treatment Adherence After Brain Injury

NCT04221009

COMPLETED

Exoskeleton Footwear to Improve Walking

NCT04337554

COMPLETED

Epidemiology, Immunology and Clinical Characteristics of COVID-19 (EPIC3)

NCT05764083

COMPLETED NA

Effect of Medication Management at Home Via Pharmacy Home Televisits

NCT04340570

COMPLETED Phase 2

Hormonal Intervention for the Treatment in Veterans With COVID-19 Requiring Hospitalization

NCT04397718

COMPLETED NA

Evaluation of Implementing FLOW

NCT04193033

COMPLETED

BRAIN, Symptoms, and Physical Activity in COPD

NCT04291131

COMPLETED NA

One-day Life Skills Workshop for Veterans With TBI, Pain, and Psychopathology: Evaluating Efficacy and Mechanism of Change

NCT04143243

COMPLETED Phase 2

Neuromodulation Techniques After SCI

NCT04241250

COMPLETED

Improving Colonoscopy Quality for Colorectal Cancer Screening in the National VA Healthcare System

NCT04389957

COMPLETED NA

CMAP Refinement for Pressure Injury Prevention

NCT04309864

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Phase Distribution

PhaseTrial count
Phase 1 89
Phase 2 147
Phase 3 55
Phase 4 69

What is open in the VA Office of Research and Development pipeline

291 recruiting of 1,668 indexed (17% open); 1,108 completed (66%).

Phase mix: 124 late (III/IV) vs 236 early (I/II) (early-phase heavy).

Top condition: Post Traumatic Stress Disorder (45 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

VA Office of Research and Development: open-pipeline peers nationwide

Peers matched on 1,668 registered trials and 17% open enrollment, not the therapeutic-area sidebar.

VA Office of Research and Development sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,000 10%12%14%16%18% Total trials Recruiting share VA Office of Research and DevelopmentUniversity of California, San FranciscoDuke UniversityStanford UniversityWashington University School of MedicineUniversity of South FloridaImmunityBioOld Dominion UniversityTexas Tech University
VA Office of Research and Development sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

VA Office of Research and Development sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,668 trials (± recruiting share)

Sponsors near 17% open enrollment (± trial volume)

What to do with this VA Office of Research and Development page

1,668 registered trials is a research-attention snapshot, not an endorsement of VA Office of Research and Development or any single study.

  • 291 of VA Office of Research and Development's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Post Traumatic Stress Disorder is the condition VA Office of Research and Development studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Post Traumatic Stress Disorder trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. VA Office of Research and Development pipeline card: 1,668 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.